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All Journal Jurnal Gizi dan Pangan JURNAL GIZI INDONESIA Nurse Media Journal of Nursing Journal of Nutrition College Psikohumaniora: Jurnal Penelitian Psikologi Holistic Nursing and Health Science Medica Hospitalia Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Penyakit Dalam Indonesia International Journal of Cell and Biomedical Science
Muchlis Achsan Udji Sofro
2Staf Pengajar Bagian Ilmu Penyakit Dalam FK UNDIP/RSUP Dr. Kariadi Semarang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Penyakit Dalam Indonesia

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Proportion of Depression Symptoms and Its Relationship with ARV Therapy: A Study at the VCT Clinic, Dr. Kariadi General Hospital Sofro, Muchlis Achsan Udji; Raharja, Tommy; Haidati, Titis; Sari, Linda Kartika; Jusup, Innawati
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 2
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Introduction. Indonesia has the second largest HIV burden in Asia. The prevalence of depression in HIV/AIDS is 2-10 times higher than the general population, influenced by biological, environmental, psychological, and demographic factors. Data on the proportion of depression symptoms in HIV/AIDS patients and their relationship to biological factors are still limited, which needed for better treatment of HIV/AIDS. This study aimed to determine the prevalence of depression and its relationship to the biologic factors of ARV therapy (ART) in HIV/AIDS patients.Methods. Cross-sectional study was conducted among 142 HIV/AIDS patients undergoing ARV treatment at RSUP. Dr. Kariadi in January – March 2021. Demographic data, ART, ART type, side effects, ARV use duration, viral load, and CD4 cell count were obtained from medical records. The incidence of depression was assessed by the Beck Depression Inventory II (BDI-II).Results. The proportion of depression symptoms was 48.6%, consisting of mild depression (26.1%), moderate depression (17.6%), and severe depression (4.9%). Multivariate analysis resulted a significant relationship between the incidence of depression and biological factors, consisting of ART side effects, ART use duration, and CD4 cell count. Meanwhile, there was no significant relationship between the incidence of depression with the ART type and viral load. Conclusion. The proportion of depression symptoms in HIV patients undergoing ART is 48.6%. It is concluded that biological factors can affect the proportion of depression in patients with ART.
The Distinction in Level of Stress, Anxiety, and Depression between Efavirenz with Nevirapine Therapies (Study on HIV/AIDS-infected patients at VCT-CST clinic Dr.Kariadi Hospital Semarang) Muflihatunnaimah, Muflihatunnaimah; Fitrikasari, Alifiati; Sofro, Muchlis Achsan Udji
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 2
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Pemberian Antibiotik Dini Berpengaruh terhadap Mortalitas COVID-19? Sofro, Muchlis Achsan Udji
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 4
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Coronavirus disease 2019 (COVID-19) merupakan infeksi saluran napas yang diakibatkan oleh severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Data di seluruh dunia sampai akhir Juni 2022 menunjukkan bahwa COVID-19 telah menyebabkan 6,2 juta kematian dengan jumlah 530 juta kasus.
The Differences of Marital Satisfaction of ODHA Couples with and without Depression Symptoms Salahudin, Muhammad Ismail; Fitrikasari, Alifiati; Sofro, Muchlis Achsan Udji; Julianti, Hari Peni
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 3
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Introduction. HIV/AIDS disease has caused physical, social, and emotional problems to infected individuals and their spouses. ODHA couples have a prevalence of depression symptoms with physical complaints, which amounted to 12.7%. There is a relationship between love, communication, and physical intimacy to satisfaction in marriage. Depression in ODHA couples is correlated with marital satisfaction. This study aimed to analyze the differences of marital satisfaction of ODHA HIV negative couples who experience depression symptoms with ODHA who do not experience depression symptoms Methods. The research design was cross-sectional. The samples were 52 official couples of ODHA aged 18-60 years who had outpatient treatment in Poly of Infection Tropical RSUP. Dr. Kariadi Semarang and met the criteria of research inclusion. Sampling technique was conducted with consecutive sampling method. Depression status was measured by the beck depression inventory (BDI) instrument and marital satisfaction was measured by ENRICH marital satisfaction scale (EMS). Processing and data analysis using SPSS program. The relationship analysis test using chi-square test. Results. Subjects who did not experience depression 78.8% and those with depression 21.2% consisted of mild 9.6%, moderate 11.6%, and severe 0%. No subjects were found to be unsatisfied with their marriage, 55.8% were very satisfied and 44.2% were satisfied. There was no significant difference between marital satisfaction of ODHA HIV negative couples with depression symptoms and without depression symptoms (p = 0,595). There was a significant difference between the marital satisfaction of ODHA HIV negative couples with depression symptoms and without depression symptoms in communication (p = 0.021), conflict resolution (p = 0.025), use of leisure activities (p = 0.025), and sexual activities (p = 0.007) Conclusion. There was no difference between the marital satisfaction of ODHA HIV negative couples with depression symptoms and without depression symptoms. There was a significant difference between the marital satisfaction of ODHA HIV negative couples with depression symptoms and without depression symptoms in communication, conflict resolution, the use of leisure activities, and sex activities.
Association between Stigma, ARV Therapy and Complications ofPsychiatric Disorders iIn HIV / AIDS Patients Wicaksono, Yamaji Adi; Fitrikasari, Alifiati; Sofro, Muchlis Achsan Udji; Peni, Hari
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 1
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Introduction. Stigma and discrimination among HIV/AIDS patients cause varrious problems such as physical, psychological, and social. Therefore, its management requires comprehensive intervention. Antiretroviral therapy improves the patient’s clinical course, but may lead to neuropsychiatric complications especially anxiety disorders, depression, and psychotic disorders. This study aimed to know the associationbetween stigma,ARV therapy and complications of psychiatric disorders of HIV patients. Methods. A cross-sectional study was conducted among HIV/AIDS patients undergoing antiretroviral therapy in VCT-CST RSUP dr. Kariadi and RSUD RAA Soewondo Pati. Subjects were recruited using consecutive sampling method. Asessment of disorders and stigma was conducted using Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and Questionnaire scale perception of PLWHA on community HIV/AIDS stigma. Analysis was performed using SPSS program. Correlation test analyzed with chi square test. Results. Total of 102 subjects were included in this study. The majority of subjects was male (51%) and the age mean value was 35.88 (SD 8.24) years. The most common type of antiretroviral drugs bas lamividine+zidovudine) + nevirapine (52.9%). The highest stigma scale of PLHIV was 95.1% positive stigma. Characteristics of psychiatric disorders consisted of 89.2% experienced psychiatric disorders, most depression 30.4%, and 6.9% psychotic disorders. Analysis showed that there was a statistically significant association between type of ARV therapy and psychiatric disorder. There was no statistically significant association between stigma and psychiatric disorders. Conclusions. There is an association between type of ARV therapy andpsychiatric disorders, but no association found between stigma and psychiatric disorders
Co-Authors Alifiati Fitrikasari Anak Agung Gede Sugianthara Anindita, Yohana Prima Ceria Anisah, Retno Lusmiati Anjani, Gemala Ardani, Yanuar Ari Suwondo Ariani Ariani Arifah, Meika Rahmawati Chairunnisa, Andita Darmono Dessy Triana Ema Hidayanti Franzeska Anna Dewi Mursita Widinartasari, Franzeska Anna Dewi Mursita Gede Arya Bagus Arisudhana Gunasari, Lala Foresta Valentine Haidati, Titis Hari Peni Julianti Hindaryani, Nurul Ilham Uddin Innawati Jusup Joyeti Darni K. Heri Nugroho HS, K. Heri Kis Djamiatun Kusmiyati Tjahjono Linda Kartika Sari Martini Martini Megah Andriany Minuljo, Tania Tedjo Mochamad Arif Nugroho Mohammad Sulchan Muflihatunnaimah, Muflihatunnaimah Muhammad Ali Sodiq, Muhammad Ali Peni, Hari Piriyasart, Jitlada Pratama, Yanuar Surya Raharja, Tommy Ratmawati, Ratmawati S.S, Darmono Salahudin, Muhammad Ismail Sammy, Alwi Siti Fatimah-Muis, Siti Suparno Suparno Tjokorda Gde Dalem Pemayun Tri Nur Kristina Tri Winarni Agustini Udin Bahrudin, Udin Untung Sujianto Wicaksono, Yamaji Adi Widiastuti, Yuliati