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All Journal Buletin Agrohorti e-Journal Pustaka Kesehatan Jurnal Ilmu-Ilmu Pertanian Indonesia Folia Medica Indonesiana Journal of Agromedicine and Medical Sciences Global Medical and Health Communication KOMUNIKA Syntax Literate: Jurnal Ilmiah Indonesia Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Bioindustri Community Development Journal: Jurnal Pengabdian Masyarakat Indonesian Journal of Global Health research International Journal of Educational Research and Social Sciences (IJERSC) INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Idarah Tarbawiyah: Journal of Management in Islamic Education Jurnal Pengabdian Pada Masyarakat Indonesia (JPPMI) ALLURE JOURNAL Jurnal Hilirisasi Technology kepada Masyarakat (SITECHMAS) Jurnal Riset Rumpun Ilmu Pendidikan (JURRIPEN) Jurnal Akademik Pengabdian Masyarakat Journal Innovation In Education Journal of Bioindustry
Sugiyanta Sugiyanta
Faculty Of Medicine, Jember State University, Jember
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Folia Medica Indonesiana

 1 
Influence of Administering Watermelon Rind Water Extract (Citrullus vulgaris Schard) on Glucose Level of Male White Rats (Rattus norvegicus) Induced with Streptozotosin Asari, Hasyim; Sugiyanta, Sugiyanta
Folia Medica Indonesiana Vol. 56 No. 3 (2020): September
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.488 KB) | DOI: 10.20473/fmi.v56i3.24528

Abstract

Watermelon rind water extract contain of citrulline. Citrulline is a precursor of generating Nitric Oxide (NO). NO possibly reduced the level of blood glucose in streptozotosin-induced diabetic rats. This study was a laboratory experimental study completely randomized design. A number of 30 male albino Wistar rats weighting 100 – 200 gr were devided into six groups (N=5), with group 1 served as normal control group. The other groups were given streptozotosin to induced diabetes mellitus. The rats in control diabetic group were given CMC 0,5%, the others were given watermelon rind extracs for 8 days with different doses for each group. The results showed that serum glucose levels in posttest control group was significantly different, from that group of the watermelon rind extract 250 mg/kg bw/day (p = 0,000), groups of watermelon rind extract 500 mg/kgbw/day (p = 0,000) and groups of watermelon rind extract 1000 mg/kgbw/day (p = 0,000). The level of triglyceride in postest control was significantly different from that group of the watermelon rind extract 250 mg/kg bw/day (p = 0,000), groups of watermelon rind extract 500 mg/kgbw/day (p = 0,000) and groups of watermelon rind extract 1000 mg/kgbw/day (p = 0,000).The conclusion, the watermelon rind water extrac can be used to reduced glucose serum level (250, 500, 1000mg/kg bw) with the optimal dose was 500 mg /kgbw/day with the optimal dose was 1000 mg /kgbw/day. 
Co-Authors Akmal, Firdaus Al Munawir Al-Kattani, Abdul Hayyie Alfi Kamalia Amri Jahi Arrezqi, Misbakhul Asari, Hasyim Ayuwardani, Mellasanti Bagus Hermansyah Bangun Suharti Bangun Suharti Bayu Setyo Nugroho, Bayu Setyo Budi, Rahmad Setio Chita Setya Widyani Cynthia Parasetiayu Ariesty Desie Dwi Wisudanti Dhanik Sulistyarini Djoko Susanto Dodi Wijaya Dwicahyandari, Winie Septhia Dwita Aryadina Rachmawati Elly Nurus Sakinah, Elly Nurus Erfan Efendi Erma Sulistyaningsih Febrina Indrasari Furqoni, Hafith Hafith Furqoni, SP., M.Si. Ph.D. Hairrudin Hairrudin Heni Fatmawati I Gede Setiawan Adi Putra I Gusti Ngurah Agung Darma Putra I Gusti Putu Purnaba Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Islakhah, Farikhatul Jumi, Jumi Khadijah Nur Al Firdausi Kristianningrum Dian Sofiana Kunthi Kencana Makayasa Putri Kunthi Kencana Makayasa Putri, Kunthi Kencana Kurniani, Kurniani Maesaroh, Dena Ajeng Makmun Riyanto Malebra, Irawan Marhaeni, Sri Mubin, Nadzirum Nahar, M. Niki Niki Rahmawati Nur Rini Nurfahimi, Yudriani Nurfika Asmaningrum Nurmaida, Eny Pang S. Asngari Paniya Paniya Paniya, Paniya Permatasari, Okti Syah Isyani Pipiet Wulandari Purnamasari, Eva Rayyan, Muhammad Isra Rafidin Reikatiffany, Amellia Rini, Erin Puspita Sa'diyah, Maemunah Safitri, Maristia Cahya Sandi Supaya Sarah Andriani Sekarmelati, Sonea Valensita Septyawati, Ratna Setyadi, Dody Sholihah, Firdha Amaliatus Solly Aryza Sri Eka Sadriatwati Sri Wahyuni Sukma Nur Ardini Suwardi Suwardi Tina Kartika Umar Farouk Widyanti, Dika Vivi Wiediyanti, Destine Fajar Yusmar Ardhi Hidayat, Yusmar Ardhi Zaenuddin, Achmad Zahrah Febianti Zuliyatul Masnunah