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All Journal Natural Science: Journal of Science and Technology Biocelebes JURNAL PHARMASCIENCE MPI (Media Pharmaceutica Indonesiana) Pharmascience Jurnal Farmasi Sains dan Komunitas Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Biologi Tropis Adi Widya : Jurnal Pengabdian Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) FIKRAH JURNAL PENELITIAN EKONOMI DAN AKUNTANSI (JPENSI) UMI Medical Journal JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Fikrah : Journal of Islamic Education Journal of Community Engagement Research for Sustainability Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Jurnal Pengabdian Masyarakat Bangsa Jurnal Intelek Insan Cendikia Jurnal Pengabdian Farmasi dan Sains Jurnal Sains dan Kesehatan

Evi Sulastri

Program Studi Farmasi, Fakultas MIPA, Universitas Tadulako, Palu-Sulawesi Tengah

Author-ID : 390917

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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UJI AKTIVITAS ANTIBAKTERI KRIM ASAM LAURAT TERHADAP Staphylococcus aureus ATCC 25923 DAN Pseudomonas aeruginosa ATCC 27853 Evi Sulastri; Mappiratu Mappiratu; Annisa Kartika Sari
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Lauric acid is a saturated fatty acid found in fatty/vegetable oils, especially in palm oil. Lauric acid was reported to posses antiviral and antibacterial property. This study aims to determine the effect of the concentration variance of lauric acid in cream on the stability of the cream physical quality and antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. In this research, lauric acid concentration in cream was varied in 10%, 20%, and 30% and then tested for antibacterial activity using hole plate technique. The results of the evaluation of lauric acid cream preparation of Formula 1, Formula 2 and Formula 3 showed that the organoleptic and homogeneity tests of all formula was no difference during storage time, but the result of pH, viscosity, and dispersive power of all formula has difference during storage time (28 days). The antibacterial test results showed that the highest inhibition diameter was found in the use of lauric acid concentration of 30% for S.aureus (21.589 mm ± 0.18) and P.aeruginosa (14.25 ± 0.37 mm). Based on statistical analysis of the cream produced from the three concentrations of lauric acid, they were not stable because there are significant differences in pH, viscosity, and dispersive power during storage time (28 days). Keywords: lauric acid, antibacterial cream, Staphylococcus aureus, Pseudomonas aeruginosa.

GEL ANTI JERAWAT EKSTRAK DAUN BUTA-BUTA (Excoecaria agallocha L.) DAN PENGUJIAN ANTIBAKTERI Staphylococcus epidermidis Ika Olivia Borman; Yusriadi Yusriadi; Evi Sulastri
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

Buta-Buta (Excoecaria agallocha L.) leaf is a type of mangrove plants that has antibacterial activity againtsbacteriacausing acne, Staphylococcus epidermidis,. This study aims to formulate buta-buta leaf extract with the concentration of 12.5 % into anti-acne gel using two gels, namely HPMC 8% (Formula 1) and Carbopol 940 2%(Formula 2). Antibacterial activity test was carried out by agar diffusion method using well. The stability and antibacterial activity data during 28 days were analyzed statistically using unpaired t-student with a degree of confidence of 95% (α = 0.05). The evaluation results of anti-acne gel form of buta-buta leaf extract in Formula 2 showedbetter characteristics than Formula 1, which include organoleptic examination, homogenity, pH and viscosity during 28 days. The antibacterial test showed the diameter of inhibition zone of Formula 2 is 11.03 mm ±0,01. The statistic analysis showed a significant difference between Formula 2 with a positive control (klindamisin gel).

Uji Stabilitas Dan Aktivitas Antioksidan Mikroemulsi Likopen Tomat (Solanum lycopersicum L.): Stability Test and Antioxidant Activity of Tomato Lycopene (Solanum lycopersicum L.) Microemulsion Evi Sulastri; Mohamad Ikram; Yuliet Yuliet
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 3 No. 1 (2017): (March 2017)
Publisher : Universitas Tadulako

Lycopene is a class of keratonoid that have been proven has antioxidant activity but has limited solubility in water. So as to boost their solubility, in this study conducted in the form of microemulsion formulations. This study aims to get a tomato lycopene extract microemulsion which is stable and has antioxidant effects. The research was initiated to test the antioxidant power of tomato lycopene extract in vitro against DPPH. Tomato lycopene extract microemulsion is formulated based on the optimization of the composition of the base consisting of the VCO as the oil phase, tween 80 as surfactant and glycerin as cosurfactant. Preparations produced were tested for antioxidant activity and their physical and chemical stability testing which include: organoleptic, viscosity, globule size and pH during 28 days of storage. The results showed that tomato lycopene extract formula microemulsion stable composition of tomato lycopene extract 0.3%, VCO 15%, tween 80% and 35% glycerin. The test results obtained physical stability of the microemulsion formula elected tomato lycopene extract has a distinctive scent of aromatic, orange, thick, globule size of <5 μm, viscosity (600, 33 ± 69.29 to 746 cPs ± 8.32), and pH ( 6.27 ± 0.20 to 6.79 ± 0.10). As very strong antioxidant activity with IC50 value of 29.07 ppm.

Mikroenkapsulasi Antosianin Kulit Buah Kakao (Theobroma cacao L.) Dengan Metode Koaservasi Kompleks: Microencapsulation of Anthocyanine of Kakao (Theobroma cacao L.) Bark with Complex Coaservation Lubis, Siska Syahfitri; Sulastri, Evi; Zubair, Muhammad Sulaiman
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 4 No. 2 (2018): (October 2018)
Publisher : Universitas Tadulako

Anthocyanin is a class of antioxidants that are widely found in the skin of cocoa fruit (Theobroma cacao L.). Anthocyanin degradation occurs not only during the extraction process from plant tissues but also during the storage process. The microencapsulation process can protect the active substance from environmental influences or improve the stability of the preparation. This study aims to characterize anthocyanin microcapsules from cocoa (Theobroma cacao L.) fruit peel using a complex coacervation method, therefore, it can provide economic value added from this plant. Anthocyanin microencapsulation was formulated using a coating of gelatin: arabic gom with different concentrations of 1:1, 3:2, and 2:1. Microcapsule characterization was organoleptic and morphological test, particle size distribution, moisture content test, absorption efficiency, recovery test, antioxidant activity of the preparation, and FTIR analysis. The results showed that extract yield was 39.82%, optimum microcapsule characterization was obtained from 1: 1 concentration with 36.65% recovery test, 80.40% absorption efficiency, and antioxidant activity with IC50 of 20.52 ppm.

Mikroenkapsulasi Likopen dari Buah Tomat dengan Metode Penguapan Pelarut: Microencapsulation of Lycopene from Tomato Fruit by Solvent Evaporation Method Sulastri, Evi; Ibrahim, Nurlina; Budiarti, Suci
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 1 (2019): (March 2019)
Publisher : Universitas Tadulako

Lycopene is a carotenoid group easily damaged due to the oxidation process (light, oxygen and temperature) and isomerization during storage. This damage can be minimized by microencapsulation processes. The objective of this study was to develop novel microencapsulation of lycopene extracts from tomato fruit by solvent evaporation method using ethyl cellulose as wall materials and to select the optimum formulation. Three microcapsule formulations were prepared containing the ratio of lycopene and ethyl cellulose (L:ES) of 1:1, 1:2 and 1:3. The morphology of the microcapsules was analysed by optical microscopy and scanning electronic microscopy. The encapsulation efficiency, particle size, recovery yield and moisture content were also examined. The result showed that all microcapsule formula were aggregated and irregular in shape with encapsulation efficiency of 6.13- 19.43%, moisture content of 1,63- 7,52%, recovery yield of 81-98,12% and particle size of 46,2-86Âµm. Microcapsule with a ratio 1:3 (L:ES) was the most optimum formula based on a maximum encapsulation efficiency than the others

Formulation and Antioxidant Activity of Clay Mask of Tomato (Solanum lycopersicum L.) Lycopene Extract with Variation of Concentration of Kaoline and Bentonite Bases): Formulasi dan Aktivitas Antioksidan Masker Clay Ekstrak Likopen Tomat (Solanum lycopersicum L.) dengan Variasi Konsentrasi Basis Kaolin dan Bentonit Syamsidi, Armini; Syamsuddin, Alifah Magfirah; Sulastri, Evi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15462

Free radicals can cause damage to human skin, so antioxidants are needed to counteract the negative effects of these free radicals, for example preparations in the form of face masks. Tomatoes (Solanum lycopersicum L.) contains nutritious substances, namely lycopene which can be useful as an antioxidant for the skin. This study aims to determine the effect of variations in kaolin and bentonite bases on physical characteristics and antioxidant activity of tomato lycopene extract clay mask, and to determine the best formula. Tomato lycopene extract was modified into a microemulsion preparation to maintain the stability of antioxidant activity. Kaolin and bentonite used as bases had various concentrations in each formula, namely F1: 15% and 2%, F2: 20% and 1.5%, F3: 25% and 1%, F4: 30% and 0.5%. The results showed that the four clay mask preparations were homogeneous and no change in color, shape and aroma. The pH test on the four formulas was F1: 4.33 Â± 0.35, F2: 5.58 Â± 0.24, F3: 6.48 Â± 0.22, and F4: 7.34 Â± 0.08. The viscosity test on the four formulas was F1 : 20213.3 Â± 140.4, F2: 24133.3 Â± 83.26, F3 29080 Â± 105.83, F4 33293.3 Â± 378.06. The spreadability test was F1 6.59 Â± 0.24, F2 5.59 Â± 0.16, F3 4.85 Â± 0.11, F4 7.84 Â± 0.05. The test time for the preparation to dry was F1 19.02 Â± 0.36, F2 15.33 Â± 0.54, F3 11.27 Â± 0.42, F4 8.24 Â± 0.50. F1 and F2 are very easy to clean. Meanwhile, F3 and F4 are easy to clean. The best formula for clay masks is the F3 preparation where the concentration of kaolin is 25% and bentonite is 1%. It also showed the lower antioxidant activity (741.34 Âµg/mL) than other formulas.

Co-Authors Aceng wildan Jaelani Adjiwiyasa, Anshar Tejo Annisa Kartika Sari Armini Syamsidi Asriana Sultan Budiarti, Suci Cristadeolia Oktaviani Cristadeolia Oktaviani, Cristadeolia Dinda Rahmiyati Djanun, Eulistinah Edy Ervianto Eka Afrika Friskilla Friskilla Ida Royani Ika Olivia Borman Imam Makruf Ince Agus Nurcholis Indarwati Abdullah, Rezky Putri Jamaluddin Jamaluddin Karim, Abdul Mubdi Ardiansar Arifuddin Karim, Marzelina Kartika, Nursiti Sari Kezia, Deswita Lubis, Siska Syahfitri Manurung, David Pratama Manurung, Diva Cholis Mappiratu Mappiratu Marpaung, Noveri Mohamad Ikram Muhammad Sulaiman Zubair Nandiska Maladjili Nawawi, Muh Nela Sharon Ni Ketut Sumarni Ningsih, Septia Warda Nurlina Ibrahim Nuur Aanisah Oryza Sativa Pramita Putri Pramita Putri Rachmat Faisal Syamsu, Rachmat Faisal Rahma Sari, Intan Rahman, Dinda Briliany Ritha Pratiwi Rohaya, Rohaya Sakti Hutabarat Selnisistia Hidayani Sianturi, Gabe Daniel Simamora, Seltia Ledi Sara Simanjuntak, Anwar Ribert Siti Maemunah Sri Sulistiana Sulaiman , Sri Sulistiana Sulaiman, Sri Sulistiana Supriyanto Supriyanto Syamsuddin, Alifah Magfirah Tampubolon, Cindy Artha Ully Vitasari Vitasari Wanti, Sri Yuliet Yuliet Yusriadi Yusriadi

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