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Journal : Indonesian Journal of Pharmaceutical Science and Technology

The Antiplaque Efficacy and Effectiveness of Activated Charcoal Toothpaste of Elaeis guineensis in Smokers Uce Lestari; Syamsurizal Syamsurizal; Yustika Trisna
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 3, No. 1 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.32664

Abstract

Plaque on the teeth of smokers comes from cigarette smoke tar that settles on the surface of the teeth and roots of the teeth, causing the tooth surface to become rough and easier to stick with food debris and germs that will react making it easier for plaque to form. This study was aims to determine the safety and effectiveness of removing plaque in palm shell activated charcoal toothpaste with a concentration of 12% calcium carbonate combination of 25%. The content of calcium carbonate as an abrasive against the dental plaque of active smokers. The method used was measurement the plaque index score according to Turesky before and after using toothpaste on 20 panelists of active smokers. The decrease in plaque index in the use of toothpaste by using Wilcoxon's non-parametric statistical test, namely P = 0.000 (Sig <0.05). The results showed that toothpaste in the first week was able to reduce dental plaque by 59% compared to positive control by 45% and without activated charcoal by 34%. Toothpaste and positive control in the second week were able to remove dental plaque by 100%, while toothpaste without activated charcoal and calcium carbonate was only able to remove dental plaque by 68%. It can be concluded that palm shell activated charcoal toothpaste with a concentration of 12% combined with 25% calcium carbonate is safe and effective in removing plaque on the teeth of smokers.Keywords: dental plaque, efficacy, palm shells
FORMULATION AND TEST OF ANTIOXIDANT ACTIVITY OF GEL MASK PEEL OFF FROM SURIAN (Toona Sinensis) LEAF ETHANOL EXTRACT IN VITRO Uce Lestari; Muhaimin Muhaimin; Yuliawati Yuliawati
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.46456

Abstract

Free radicals can cause damage to skin oxidative cells which will have an impact on aging. This can be shown by the appearance of wrinkles, dull looking skin, black spots (spots) and easily dry skin texture. Antioxidants are compounds that can overcome the bad effects of free radicals. The use of the effects of antioxidants for preparations aimed at facial skin, is better if it is made with cosmetic dosage forms for topical use compared to oral use. One example of this cosmetic preparation is the peel off gel mask. One source of antioxidants comes from the ethanol extract of surian leaves. The aim of the study was to make a gel peel off mask preparation containing antioxidants from surian leaf extract. Surian leaves were extracted by maceration using ethanol, the antioxidant test used the DPPH method. The formulation of peel off gel masks used various extract concentrations, namely 2.5%; 5% ; 7.5% and 10% . Tests for physical characteristics have met the requirements of SNI with organoleptic covering brownish clear color, characteristic aromatic odor of surian leaves, thick form. pH value (4.87-5.47), Viscosity (14088.16-44722.81 cps), spreadability (5.26-5.69 cm), adhesion power (4.08-4.56 seconds) and drying power (22.58-24.02 minutes). The peel off gel mask with the best antioxidant value is formulation 5.