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All Journal Indonesia Journal of Halal JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Mattawang: Jurnal Pengabdian Masyarakat Archives of The Medicine and Case Reports Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Prosiding University Research Colloquium Journal of Halal Science and Research Jurnal Kefarmasian Indonesia Pharmacon: Jurnal Farmasi Indonesia
Pri Iswati Utami
Fakultas Farmasi, Universitas Muhammadiyah Purwokerto
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : JSFK (Jurnal Sains Farmasi

 1 
Formulasi dan Uji Sifat Fisik Sediaan Lulur Krim dari Ekstrak Etanol Daun Sirsak (Annona muricata L.) serta Penentuan Aktivitas Antioksidannya Hakim, Zainur Rahman; Meliana, Dewi; Utami, Pri Iswati
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 2 (2020): J Sains Farm Klin 7(2), Agustus 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.2.135-142.2020

Abstract

The ethanolic extract of soursop leaves (Annona muricata L.) is reported as an antioxidant agent with an IC50 value of 14.48 µg/mL. This research aimed to examine physical characteristics and investigate the antioxidant activity of the ethanolic extract of soursop leaves in a scrub cream. Soursop leaves powder was extracted with 70% ethanol and formulated as scrub cream at the concentration of 1.4%, 2.8%, and 4.2%, then evaluated for physical characteristics. The antioxidant activity was evaluated using DPPH (1.1-diphenyl-2 picrylhydrazyl) method. The result showed that the scrub cream at all concentrations tested fulfilled all physical characteristics required for good topical preparations. These included organoleptic, homogeneity, viscosity, pH, spreadability, and adhesion. The IC50 value of the scrub cream at the concentration of 1.4%, 2.8 %, and 4.2% were 30.72, 26.82, and 24.03 µg/mL, respectively. The IC50 values indicated that the scrub creams exhibit radical scavenging activities which categorized as strong activity antioxidants.
Co-Authors Abdul Manan Agus Siswanto Angga Tiya Warma Sarigih Ani Puji Lestari Anjar Mahardian Kusuma Anwar Rosyadi Asih Mahmudah Sanusi Asmiyenti Djaliasrin Djalil Binar Asrining Dhiani Dewi Andriyani Didik Setiawan Diniatik Diniatik Dwi Hartanti Eka Prasetyo Agung Pambudi Fajrin Noviyanto, Fajrin Febriyanti Diah Puspita Sari, Febriyanti Diah Puspita Fendi Nugroho Fitri, Hidayah Anisa Hakim, Zainur Rahman Hasnita Ika Yuniastuti Indah Puji Lestari Indri Hapsari Irfan Nugraha Khamdiyah Indah Kurniasih Listiowati Listiowati Marsha, Ardiana Meliana, Dewi Muchammad Ade Firmansyah, Muchammad Ade Mufidah, Aidatul Mufti Kharismawati Muhammad Irfan Firdaus Mulyani, Ayu Nanang Munif Yasin Nur Aida Masyitoh Nur Ida Dwi Retnani Pudji Lestari Retno Wahyuningrum Rizki Widyaningsih Roselina Wulandari Ryandita, Ika Sabikis Sabikis Sabikis Sabikis, Sabikis Shafiyatun, Arina Nur Nida Siti Helmyati Sochib Ibnu Fajar Sundhani, Elza Suparman Tjiptasurasa Tjiptasurasa, Tjiptasurasa Wahyu Utaminingrum Wiranti Sri Rahayu Wiranti Sri Rahayu