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Journal : Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)

The Relationship Between Viral Load Levels and CD4+ Count with the Incidence of Opportunistic Infections in HIV/AIDS Patients at Ibnu Sina Hospital Makassar Daud, Nur Ramahdani; Vitayani, Sri; Harahap, Muhammad Wirawan; Waspodo, Nurelly Noro; Irmayanti, Irmayanti
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1612

Abstract

Background: HIV/AIDS is a global health problem that continues to be a challenge, especially in developing countries. One important aspect in the management of HIV/AIDS is the monitoring of viral load and CD4+ levels which serve as indicators of the patient's immune status. As the disease progresses, HIV/AIDS patients are at high risk of opportunistic infections that can worsen health conditions and shorten life expectancy. Objective: To determine the relationship between viral load and CD4+ levels in HIV/AIDS patients at Ibnu Sina Hospital. Method: Analytic observational research method with cross sectional approach, the research subjects were 10 subjects for viral load examination and 32 subjects for CD4+ examination. Results: The highest percentage of opportunistic infections was in oral candidiasis infection as many as 16 people (50%). The chi-square test showed a significant relationship between CD4+ levels and opportunistic infections in HIV/AIDS patients at Ibnu Sina Hospital Makassar with a p-value of 0.000 while for viral load could not be determined because secondary data were incomplete. Conclusion: There is a significant relationship between CD4+ levels with opportunistic infections in patients with HIV/AIDS at Ibnu Sina Hospital Makassar.
Analysis of complications in type 2 diabetes mellitus patients at Ibnu Sina Hospital in 2023 Handayani, Dewi Sri; Vitayani, Sri; Harahap, Muhammad Wirawan; Gani, Azis Beru; Nur, Muh Jabal
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1664

Abstract

Background: Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia due to decreased insulin secretion or insulin resistance. T2DM can lead to microvascular complications, such as neuropathy, nephropathy, and retinopathy, as well as macrovascular complications, including heart disease, stroke, and peripheral vascular disease. Objective: This study aimed to determine the relationship between age, gender, HbA1c levels, and the duration of T2DM with the complications experienced by T2DM patients at Ibnu Sina Hospital Makassar. Method: This was a descriptive observational study with a cross-sectional design involving 40 T2DM patients. Data were collected using secondary patient records. Results: The most common complication found was diabetic neuropathy, affecting 19 patients (47.5%). Statistical analysis using the chi-square test showed a significant relationship between age and complications (p = 0.002) and between HbA1c levels and complications (p = 0.004). Gender showed no significant relationship with complications. The duration of T2DM could not be analyzed due to incomplete data. Conclusion: Age and HbA1c levels are significantly associated with the occurrence of complications in T2DM patients at Ibnu Sina Hospital in 2023. Regular monitoring and strict glycemic control are essential to minimize the risk of complications.