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All Journal Jurnal Kedokteran Syiah Kuala Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Nusantara Medical Science Journal Jurnal Keperawatan Padjadjaran Jurnal Kesehatan Prima Oceana Biomedicina Journal Jurnal Ilmu Kefarmasian Indonesia J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Medical and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Indian Journal of Forensic Medicine & Toxicology International Islamic Medical Journal journal of Basic Medical Veterinary Oceana Biomedicina Journal Cerdika: Jurnal Ilmiah Indonesia Jurnal Kedokteran Meditek
Yuani Setiawati
Departemen Farmakologi, Fakultas Kedokteran, Universitas Airlangga, Surabaya, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : International Islamic Medical Journal

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Antibacterial Effect of Streptomyces sp-MWS1, Streptomyces sp-MWS3, and Streptomyces sp-MWS6 ON Klebsiella pneumoniae Producting Extended-Spectrum β-Lactamase (ESBL) Setiawati, Yuani; Retnowati, Wiwin; Basori, Achmad
Jurnal Medis Islam Internasional Vol 1 No 1 (2019): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v1i1.1326

Abstract

Klebsiella pneumoniae as an opportunistic pathogen can cause nosocomial infection. The main concern on this bacterium is directed on the extended-spectrum β-Lactamase (ESBL)-producing Klebsiella pneumoniae. The therapy of ESBL-producing Klebsiella pneumoniae infections is very limited because of its multidrug resistance. It had been found new local isolates Streptomyces sp-MWS1, Streptomyces sp-MWS3, and Streptomyces sp-MWS6 in mangrove East Coast of Surabaya. These isolates have potential to produce antibiotics (Retnowati, 2008). This study was aimed to prove these isolates may inhibit the growth of ESBL-producing Klebsiella pneumonia. The test of antibacterial activity of Streptomyces sp-MWS1, Streptomyces sp-MWS3, and Streptomyces sp-MWS6 using the modification Agar print method against clinical isolates of ESBL-producing Klebsiella pneumoniae. The diameter of inhibition zone (mm) formed shows activity of these isolates. The profiles of antibacterial activity of Streptomyces sp-MWS1, Streptomyces sp-MWS3, and Streptomyces sp-MWS6 were different in terms of periode required to reach peak activity, duration of activity and inhibition zone diameter produced during 10 days of observation. Streptomyces sp-MWS3 reached the peak activity most rapidly on day 3 with the largest inhibition zone diameter of 9 mm in ESBL-producing Klebsiella pneumoniae. There were significant differences in inhibition zone diameter between Streptomyces sp-MWS1, Streptomyces sp-MWS3, and Streptomyces sp-MWS6 against ESBL-producing Klebsiella pneumoniae.
The Use of Prophylactic Antibiotics on Orthopaedic Procedures in an Academic Hospital in Indonesia Setiawati, Yuani; Farhadi, Azmi
Jurnal Medis Islam Internasional Vol 2 No 2 (2021): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v2i2.2155

Abstract

Background: Surgical site infections (SSIs) are common surgical complications that will increase cost of treatment. The incidence of SSI can be prevented with antibiotic prophylactic. Uncompliance using of prophylactic antibiotics is one of the factors leading to the occurrence a microbes resistance. The data on the using of prophylactic antibiotics in Indonesia is still limited. Objective: This study aims to analyze the using of prophylactic antibiotic guideline on orthopaedic surgery. Methods: The study was conducted retrospectively using data from medical records on patients who had clean and clean-contaminated orthopedic procedures from 2013 to 2016 in the standard operating room of Dr. Soetomo hospital Surabaya. We analyzed the use of prophylactic antibiotics in terms of antibiotic selection, timing of administration, and the compliance to the prophylactic antibiotic local guidelines on orthopaedic surgery. Results: Overall, patient data from 2013 to 2016 was 5246 patients. The compliance rate of prophylactic antibiotics from 2013 to 2016 was 48.3%. This level of compliance uses a selection of antibiotics, dose of administration, delivery mode, delivery time, and route of administration. Conclusion: The results of this study have shown that the prophylactic antibiotic compliance rate on orthophaedic procedures in Soetomo Hospital from 2013 to 2016 was 48,3%. Antibiotic resistance control program quite effective at increasing compliance with the use of the prophylaxis antibiotics.
Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Achmad Basori, Achmad ACHMAD RIFAI Agung Dwi Wahyu Widodo Akbar Kurniawan, Mohammad Al Alim, Muhammad Khafidin Anna Surgean Veterini Annete d’Arqom Annette d’Arqom, Annette Ardana, Arin Aurilia Arifa Mustika Asrianti, Nur Ilma Baitul Fatimah Benny Iswanto Pantoro Cindy ApriliaEkaPrasanty Citagami, Salsabila Dennia Oktavia Zahidah Hulwah Dennia Oktavia Zahidah Hulwah Dewangga Sakti Satria Kinasih Dewinta Enggar Pramesthi Djoko Marsudi Eko Budi Koendhori, Eko Budi Fadilah Fadilah Farhadi, Azmi Farhan Nurdiansyah Fatimah, Nurmawati Felicia Jiwantono Feriawan Tan Fiqih Faizara Ustadi Firda Fitra Qolbina Fitriati, Mariza Gatot Soegiarto Hasanatuluddhiyah, Nurina Indiastuti, Danti Nur Indri Safitri Mukono, Indri Safitri Isyroqiyyah, Nur Moya Izzatul Fithriyah Jihan Bobsaid Jihan Bobsaid Junaidah Yusof Khaerunnisa, Siti Kusuma Eko Purwantari Maftuchah Maftuchah Manaf, Syifa Az Zahrah Maya Hapsari Kusumaningtyas Mhd Zamal Nasution Mia Rahardjo Muflikhah Ramadhani Muflikhah Ramadhani Muhammad Khafidin Al Alim NOOR CHOLIES Nurina Hasanatuludhhiyah Nurul Wiqoyah, Nurul Pepy Dwi Endraswari, Pepy Dwi Purwanta, Marijam Puteri, Fira Adilah Qorib, Mohammad Fathul Rehatta, Nancy Margarita Rizki Awaluddin Rochmah Kurnijasanti Shazia Hafazhah Aulia Siti Khaerunnisa Siti Khaerunnisa Sri Purwaningsih Sri Purwaningsih Trisniartami Setyaningrum Vivi Permata Sari Wiwin Retnowati Wiyogo, Illona Okvita Yuri Widia, Yuri