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All Journal PHARMACON Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN Jurnal Teknosains Interest : Jurnal Ilmu Kesehatan Majalah Obat Tradisional JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA As-syifaa Jurnal Farmasi JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JURNAL PENGABDI Media Farmasi Al-Khidmah JPSCR : Journal of Pharmaceutical Science and Clinical Research Journal Syifa Sciences and Clinical Research (JSSCR) Media Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Journal Pharmacy of Tanjungpura
Isnindar Isnindar
Bagian Biologi Farmasi Fakultas Kedokteran Universitas Tanjungpura Pontianak
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Interest : Jurnal Ilmu Kesehatan

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Antibacterial Activity Of Combination Of n-Hexane Extract Of Buas-Buas Leaves (Premna serratifolia L.) And Sappan Wood (Caesalpinia sappan L.) Rissa Febriyanto; Isnindar Isnindar; Sri Luliana
Interest : Jurnal Ilmu Kesehatan INTEREST: Jurnal Ilmu Kesehatan Volume 11 Number 1 Year 2022
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/interest.v0i0.356

Abstract

Background: The plants used in this study were buas-buas leaves (Premna serratifolia L.) and sappan wood (Caesalpinia sappan L.). The people of West Kalimantan use the buas-buas leaves and sappan wood as traditional medicine, and, based on research, they have antibacterial activity. Staphylococcus aureus and Escherichia coli are bacteria that cause nosocomial infections and have developed resistance to many antibiotics. This research was conducted to determine the antibacterial activity of the combination of n-hexane extract of buas-buas leaves and sappan wood. Methods: The antibacterial activity test was carried out by the agar diffusion method using a paper disc with a diameter of 6 mm. The antibacterial activity of a combination of n-hexane extract of buas-buas leaves and sappan wood in a ratio of 1:1, 2:1, and 1:2 at concentrations of 125, 250, and 500 ppm. Results: In this study, the combination of n-hexane extract of buas-buas leaves and sappan wood with various concentrations, even with increasing concentrations, did not show any inhibition zones. The factors that are thought to affect the absence of the inhibition zone are the concentration of the extract, the content of secondary metabolites, the solubility of the extract, and the length of contact time Conclusion: The combination of n-hexane extract of buas-buas leaves and sappan wood did not have antibacterial activity against Staphylococcus aureus and Escherichia coli in all comparisons and concentrations. It is recommended to test the antibacterial activity with a higher concentration
Co-Authors Adahane, Euistya Febrianti Putri Amaria, Egita Feby Ananda, Elcie Anastasia, Desy Siska Azizzah Dwi Rahmawati Azura, Dhea Nur Badaria, Lailatul Bambang WIJIANTO Cristin, Bella Dina Pratiwi, Dina Erna Prawita Setyowati Erna Prawita Setyowati Erna Prawita Setyowati Hadi Kurniawan, Hadi Hariyanto IH Hervianto, Willy Ilham Saputra Kamil, Insan Liza Pratiwi Luliana , Sri Luliana, Sri Maulidia, Yuninta Nadine, Shahira Audia Nasution, Nuraini Nur Atikah Purnamaputra, Alfred Putri, Dinda Marlinda Rafika Sari Rahmi Septiani Ricky Midi Candra Rise Desnita, Rise Rissa Febriyanto Robiyanto Robiyanto, Robiyanto Robiyanto, Robiyanto Ropiqa, Meri Saputra, Ilham Sitarina Widyarini Sitarina Widyarini Siti Nani Nurbaeti Sri Wahdaningsih Subagus Wahyuono Subagus Wahyuono Subagus Wahyuono Subagus Wahyuono Syalsabila, Regitha Rianda Tara Kamita Riduana Tarung, Albianus Febri Uray Cindy Hafinur Willy Hervianto Wintari Taurina Yuswanto Yuswanto Yuswanto Yuswanto Yuswar, Muhammad Akib Zahid, Muhammad