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All Journal Journal of Nutrition and Health Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Diponegoro International Medical Journal (DIMJ)
Titis Hadiati, Titis
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Diponegoro International Medical Journal (DIMJ)

 1 
The Effect of Folic Acid Adjuvant on Cognitive Function on Patients with Chronic Schizophrenia Sofa, Yulia Ratna; Wardani, Natalia Dewi; sari, Linda Kartika; Hadiati, Titis; Muflihatunnaimah, Muflihatunnaimah
Diponegoro International Medical Journal Vol 3, No 2 (2022): December 2022
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v3i2.15219

Abstract

ABSTRACT   Background: Schizophrenia is a severe mental disorder that associated with daily life and social function deterioration and could be accompanied with cognitive deficits. Meanwhile, hyperhomocysteinemia (HHcy) is the increasing homocysteine (Hcy) level which might be the one of biological factor in schizophrenia. In recent study with healthy subjects, it was known that there was a correlation between total Hcy level and cognitive function. Folic acid is part of water-soluble vitamin B and expected to have important role in oxidative stress by preventing hyperhomocysteinemia.Objective: This study aimed to elaborate the effect of folic acid adjuvant to improve cognitive function in chronic schizophrenia patients.Methods: This was a double-blinded randomized controlled trial with pre and post-test clinical trial design. This study included 32 patients in control group and 32 patients in treatment group. MOCA-INA score was examined in all subjects on the first day. Then, all subjects were given standard antipsychotic treatment plus folic acid adjuvant / placebo during 3 week of hospitalized treatment and 1 week of outpatient treatment. When the 4-week treatment finished, the subjects were followed by MOCA-INA post-test.Results: In this study, we had the significant difference of pre and post-test MOCA-INA score in the control group (p<0.001), significant difference of pre and post-test MOCA-INA score in the treatment group (p<0.001), and significant difference of post-test MOCA-INA score between the control and treatment group (p<0.001).Conclusion: Folic acid adjuvants significantly improved cognitive function in chronic schizophrenic patients.  
Does Self-Esteem Affect Stress Levels in Final Year Medical Students? (A Study In Final Year Medical Students, Faculty Of Medicine, Diponegoro University) Felita, Fiona; Adiwijaya, Janice Nathania; Hadiati, Titis; Fitrikasari, Alifiati; Savitri, Soesmeyka
Diponegoro International Medical Journal Vol 5, No 1 (2024): July 2024
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v5i1.22494

Abstract

Background: During young adulthood, individuals are forced to encounter countless and overwhelming challenges and responsibilities. Individuals are very prone during this period due to the fluctuation in self-esteem. Low self-esteem might significantly impact individuals as they could perceive challenges as distress, putting them at an increased risk of harming physical or mental health.Objective: To examine the relationship between self-esteem and stress levels among final year medical students, Faculty of Medicine, Diponegoro University.  Methods: This research is an observational analytic correlational study with a cross-sectional design. Samples were obtained by total sampling method involving final year medical students, Faculty of Medicine, Diponegoro University (Class of 2018). Self-esteem was measured using the Rosenberg Self-esteem Scale (RSES), and stress levels were measured using the Perceived Stress Scale (PSS-10) that had been tested valid and reliable. Data were analyzed using Spearman and Lambda Correlation Tests.Results: There were 226 subjects involved in this research. Most subjects had high self-esteem (69,5%) and moderate level of stress (67,3%). Demographic factors (gender, residency status, academic achievement and economic status) were not significantly associated with self-esteem and stress levels. However, there was a significant relationship (p=0.000) between self-esteem and stress levels with moderate negative correlation (r=-0.385).Conclusion: There was a significant relationship between self-esteem and stress levels.
The Relationship between Self-Esteem and Anxiety Levels in Final-year Medical Students Adiwijaya, Janice Nathania; Felita, Fiona; Fitrikasari, Alifiati; Sarjana, Widodo; Hadiati, Titis
Diponegoro International Medical Journal Vol 5, No 1 (2024): July 2024
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v5i1.22515

Abstract

Background: Self-esteem is an evaluation of oneself that can be positive or negative. Self-esteem affects the way individuals value and views themselves and others. Self-esteem increases gradually during young adulthood. On the other hand, anxiety disorders are also prone to occur during this time. Individuals with low self-esteem arefound to often experience symptoms of anxiety.Objective: The purpose of this study is to examine the relationship between self-esteem and anxiety levels among final year medical students, Faculty of Medicine, Diponegoro University.Methods: This research is a correlational analytic observational study with a cross-sectional design. Total sampling was used in this research involving final year medical students, Faculty of Medicine, Diponegoro University (Class of 2018). Self-esteem was assessed using the Rosenberg Self-esteem Scale (RSES), and anxiety levels were assessed using the Zung Self-rating Anxiety Scale (ZSAS) that had been tested valid and reliable. Data were analyzed using Spearman and Lambda Correlation Tests.Results: There were 226 respondents involved in this study. The majority of respondents had high self-esteem (69.5%) and a mild level of anxiety (84.1%). Gender was known to affect the level of anxiety (p=0.026) but not self-esteem. Academic achievement and residency status was known not to affect self-esteem and anxiety levels. There was a significant relationship (p=0.000) between self-esteem and anxiety levels with a moderate negative correlation (r=-0.289).Conclusion: There was a significant relationship between self-esteem and anxiety levels.
Co-Authors Adiwijaya, Janice Nathania Alifiati Fitrikasari Asikin, Hang Gunawan Clara, Jessica Felita, Fiona Hari Peni Julianti Innawati Jusup Linda Kartika Sari Mahardhika, Alain Stephano Muflihatunnaimah, Muflihatunnaimah Natalia Dewi Wardani Sarjana A.S., Widodo Savitri, Soesmeyka Setiarini, Natalia Kus Sofa, Yulia Ratna Sutaty, Witrie Widodo Sarjana AS, Widodo wimala, Dina