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All Journal BALI MEDICAL JOURNAL (BMJ) journal of internal medicine E-Jurnal Medika Udayana Media Kesehatan Masyarakat Indonesia Indonesian Journal of Tropical and Infectious Disease Universa Medicina ISM (Intisari Sains Medis) : Jurnal Kedokteran CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Journal of Global Pharma Technology Eduvest - Journal of Universal Studies Jurnal Penyakit Dalam Indonesia
I Ketut Agus Somia
Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran, Universtas Udayana-RSUP Sanglah Denpasar, Bali-Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Journal : Jurnal Penyakit Dalam Indonesia

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Kidney Disease and Its Impact on COVID-19 Patients at Sanglah Hospital Denpasar, Bali, Indonesia in 2021 Upadhana, Putu Satyakumara; Sastrawan, I Gede Gita Sastrawan; Chintya Cahyarini, I Gusti Agung Ayu; Umam, Anbiya Khairul; Putri, Amanda Trisliana Dwi; Adhyatma, I Gede Raka; Somia, I Ketut Agus
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Introduction. Besides having an impact on the respiratory system, COVID-19 also has an impact on other organ such as the kidneys. The systemic inflammatory response thought to be associated with bad prognosis of COVID-19 patients with kidney disease. This study aimed to determine the impact of kidney disease on COVID-19 patients. Methods. This study is an observational analytic study with a cross-sectional approach. The data used is secondary data from the records of confirmed COVID-19 patients who were treated at Sanglah Hospital from 1 May 2021 to 31 August 2021 using total sampling technique.Results. There were 248 patients included in this study. The majority of patients were male (52.4%) with the median overall age of the patients was 59 (range 20–92) years. Most of the patients were severe COVID-19 (65.3%). A total of 77 patients had kidney disease (31.0%) which the most common kidney disease found in patients was acute on chronic kidney disease (n=33; 42.8%). There were significant differences in hemoglobin (p<0.001), blood urea nitrogen (BUN) (p<0,001), serum creatinine (p<0.001), and procalcitonin (p<0.001) in patients classified based on kidney disease. Chi-square analysis showed that COVID-19 patients with kidney disease was correlated with sepsis [PR=2.587 (95%CI 1.750-3.824); p<0.001)], mortality [PR=1.696 (95%CI 1.114-2.583); p=0.018)], and severe COVID-19 [PR=1.513 (95%CI 1.077-2.342); p=0.040)]. Logistic regression analysis showed that COVID-19 patients with kidney disease was correlated with sepsis [PR=4.318 (95%CI 1.767-10.553); p<0,001] and mortality [PR=1.413 (95%CI 1.664-3.005); p=0.045)].Conclusion. Kidney disease increases the risk for sepsis and mortality in COVID-19 patients.
Co-Authors Adhyatma, I Gede Raka Adiputra, I Komang Hotra Aditya Darmika Amanda Trisliana Dwi Putri Anak Agung Ayu Yuli Gayatri Anak Agung Gde Putra Wiraguna Anbiya Umam Anthony Widyanata Lebuan Chintya Cahyarini, I Gusti Agung Ayu Cindy Gracia Trisina Cokorda Agung Wahyu Purnamasidhi Derian Adiguna Sutanto Desak Made Wihandani Dian, Ni Made Dewi Diksha, I Gusti Ngurah Ariestha Satya Gayatri, Anak Agung Ayu Yuli Gede Wira Mahadita Haruko Akatsu I Dewa Made Sukrama I Dewa Nyoman Wibawa I G A Gita Dewi Rahmautami I Gede Gita Sastrawan I Gede Gita Sastrawan I Gede Gita Sastrawan Sastrawan I Gede Raka Adhyatma I Gusti Agung Ayu Chintya Cahyarini I Gusti Agung Bagus Arya Wiradarma I Gusti Ayu Agung Dwi Karmila I Gusti Ayu Agung Elis Indira I Gusti Ngurah Bagus Jayanta Ananda I Komang Gede Triana Adiputra I Made Bakta I Made Siswadi Semadi I Made Susila Utama I Nyoman Bayu Andika Wiguna I Putu Pande Agus Asmara Widhiana Saputra I Wayan Putu Sutirta Yasa Ida Ayu Santhi Pertiwi Manuaba Ida Bagus Nyoman Putra Dwija Ida Bagus Putra Manuaba IGA Putri Purwanthi Jerry Junior, Darren Kadek Aprilia Sukma Dewi Ketut Ridana Wibawa Ketut Suryana Ketut Tuti Parwati Merati Komang Adya Data Agrasidi Komang Agus Trisna Amijaya, Komang Agus Trisna Komang Andjani Putri Komang Vika Nariswari Ratna Kinasih Made Yogi Oktavian Prasetia Made Yogi Oktavian Prasetia, Made Yogi Oktavian Merry Merry Merry Ni Made Dewi Dian Sukmawati Ni Made Dwi Puspawati Ni Putu Kostarika Melia Daradila Ni Wayan Winarti Nittaya Phanuphak, Nittaya NN Ayu Dewi Purnama, Giovanca Verentzia Putri, Amanda Trisliana Dwi Putu Ardy Hartadi Putu Herdita Sudiantara Putu Novi Handayani Putu SAtherogenic Index Of Plasma iatyakumara Upadhana Putu Satyakumara Upadhana Putu Sudarmika Robertus Brian Junarli Rudi Wisaksana Sastrawan, I Gede Gita Sastrawan Sawitri, Anak Agung Sagung Setiawan, Gerry Shanti, Dewa Ayu Fony Prema Siahaan, Katrin Wilentina Suteja, Richard Christian Tika Rizki Nur Laela Tuti Parwati Umam, Anbiya Khairul Upadhana, Putu Satyakumara Utama, I Made Susila Weisnawa, I Gede Purna Wulandari, Putu Kintan Yundari, Yundari