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All Journal Farmaka Teknotan: Jurnal Industri Teknologi Pertanian Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Medika Cendikia (e-Journal) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Ilmiah Farmako Bahari Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Jurnal Insan Farmasi Indonesia Jurnal Sains dan Teknologi Laboratorium Medik Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Masyarakat DEDIKASI Jurnal Sosial dan Sains Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Dani Sujana
Program Studi Diploma Farmasi, STIKes Karsa Husada Garut, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Other

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Journal : Pharma Xplore : Jurnal Sains dan Ilmu Farmasi

 1 
EFEK ANTIPIRETIK DARI PERASAN, INFUSA, DAN DEKOKTA KUNYIT (Curcuma domestica Val.) PADA MENCIT YANG DIINDUKSI LARUTAN PEPTON Dani Sujana; Dadang Muhammad Hasyim; Hasbi Taobah Ramdani; Salma Nurin Fadilah; Santi Yuliasari; Melinda Arismawati
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 6 No 2 (2021): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v6i2.1939

Abstract

Demam merupakan suatu keadaan meningkatnya suhu tubuh diatas suhu tubuh normal. Pengobatan demam dalam jangka waktu yang panjang dapat menimbulkan efek samping yang serius yaitu kerusakan hati. Curcuma domestica diketahui mengandung senyawa kimia kurkumin dan flavonoid yang berperan sebagai antipiretik yang mekanisme kerjanya menghambat enzim siklooksigenase. Di masyarakat kebanyakan metode dekokta dan infusa dari Curcuma domestica sebagai antipiretik sering dilakukan. Mengingat senyawa flavonoid tidak tahan dengan pemanasan, maka perlu dilakukan metode yang tanpa pemanasan yaitu metode perasan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian Curcuma domestica dengan metode perasan, infusa dan dekokta terhadap penurunan suhu rektal mencit yang diinduksi larutan pepton. Metode penelitian ini yaitu menggunakan metode eksperimental. Curcuma domestica memiliki efek antipiretik yang signifikan (p<0.05) terhadap mencit yang diinduksi demam dengan larutan pepton. Metode perasan memiliki efek antipiretik terbaik dari pada infusa dan dekokta.
FORMULASI KRIM EKSTRAK ETANOL DAUN REUNDEU (Staurogyne elongata (Blume) O.Kuntze) DENGAN VARIASI KONSENTRASI PARAFIN CAIR DAN SETIL ALKOHOL Diah Wardani; Nurul Nurul; Dani Sujana; Yogi Rahman Nugraha; Resta Nurseha
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 6 No 2 (2021): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v6i2.1940

Abstract

Tujuan dari penelitian ini yaitu untuk mengetahui stabilitas krim ekstrak etanol daun reundeu (Staurogyne elongata (Blume) O.Kuntze) dengan variasi konsentrasi paraffin cair dan setil alkohol. Perbandingan konsentrasi paraffin cair dan setil alkohol yang ditambahkan pada sediaan yaitu F1 (5% dan 2%), F2 (10% dan 4%), F3 (15% dan 8%). Krim dibuat dengan cara peleburan. Metode uji stabilitas dilakukan dengan cara sediaan disimpan pada suhu kamar dan suhu 40C selama 4 minggu. Parameter pengujian fisik krim yang dilakukan meliputi uji tipe emulsi, organoleptik, daya sebar, homogenitas, viskositas, pH dan daya lekat. Penelitian yang dilakukan menunjukkan bahwa sediaan krim yang memiliki stabilitas paling baik serta memenuhi standar uji yaitu formula F1 dengan konsentrasi paraffin cair 5% dan setil alkohol 2%, dengan hasil pengujian sifat fisik (siklus 0) sediaan yaitu memiliki tipe emulsi minyak dalam air (m/a), organoleptik (bau: khas lemah etanol daun reundeu; warna: hijau; tekstur: kental), memiliki tekstur yang homogen, pH 7,3, daya lekat 7,3 detik, daya sebar 5,3 cm, dan viskositas 4.783 cP.
EVALUASI EFEK ANTIPIRETIK AKAR PAKIS TANGKUR (Polypodium feei METT) PADA MENCIT YANG TERINDUKSI VAKSIN DTP-HB Hesti Renggana; Isye Martiani; Risa Susanti; Dani Sujana; Zakiah Nur Aeni
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 8 No 2 (2023): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v8i2.5928

Abstract

Fever is a state where the body's core temperature rises above normal levels. In healthy adults, the average oral temperature is around 37°C. Fever is not harmful but in certain circumstances this response is undesirable because it interferes with normal activities. The research method used is True Experimental with Posttest Only Control Group Design approach as the research design. The purpose of this study was to assess the antipyretic effect of tangkur fern root on mice induced by DTP-HB vaccine. The results showed that the extract and water fraction of tangkur fern root had antipyretic effects by reducing the fever temperature of mice during the observation time for 240 minutes. Overall, this study proves that the ethanol extract at a dose of 100 mg/kgBB is an effective dose as a candidate for antipyretic drugs.
ANALGESIC EFFECT OF INFUSA MIXTURE OF RED GINGER, TEMUKUNCI, KENCUR, LEMONGRASS AND TAMARIND ON FEMALE MICE BY WRITHING TEST METHOD. Dani Sujana; Nurul; Dadang Muhammad Hasyim; Yogi Rahman Nugraha; Diah Wardani; Mina Pertiwi; Hesti Renggana
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 8 No 2 (2023): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v8i2.5929

Abstract

Pain is an unpleasant sensory and emotional experience caused by actual or potential tissue damage. Based on systematic review studies it has been proven that red ginger, temukunci, kencur, lemongrass and tamarind have been shown to have analgesic effects both in vitro and in vivo. The purpose of this study was to determine the analgesic effect of IJTKSA. The method used in this study is a laboratory experiment with an analytical descriptive approach. The results showed that IJTKSA both concentrations of 0.02%, 0.04% and 0.08% were able to reduce the number of writhing mice. Overall, IJTKSA concentration of 0.02% has the most effective analgesic effect as evidenced by the low average total number of writhing mice during 60 minutes of observation.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL JAHE MERAH (Zingiber officinale var. Rubrum) TERHADAP BAKTERI Streptococcus mutans SECARA IN VITRO Nugraha, Yogi Rahman; Sujana, Dani; Dewi, Risma Anugrah
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 2 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i2.8019

Abstract

Infections remain a major public health challenge in Indonesia, including infections of the oral cavity caused by microorganisms such as Streptococcus mutans. Red ginger is known to contain flavonoids, phenols, essential oils, and tannins that have the potential to inhibit bacterial growth. This study aims to test the antimicrobial activity of red ginger ethanol extract against Streptococcus mutans using the agar diffusion method. The results showed that at concentrations of 10 and 20%, there was a slight increase in the zone of inhibition. However, starting from 40% concentration, the increase in concentration resulted in a larger zone of inhibition. At 60% concentration, the results were close to the positive control, and at the highest concentration of 80%, the inhibition zone reached 28.04 mm with an inhibition rate of 62.24%. Overall, the inhibitory activity showed a positive relationship as the concentration of red ginger extract increased.
KESESUAIAN RESEP BERDASARKAN ASPEK ADMINISITRATIF DAN FARMASETIK PADA PASIEN RAWAT JALAN DI PUSKESMAS WANARAJA GARUT Nurul, Nurul; Sujana, Dani; Rahayu, Sri
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 2 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i2.8020

Abstract

Completeness of administration and pharmacology in prescriptions can minimise or reduce the occurrence of medication errors. This study aims to look at the description of the suitability of administrative and pharmaceutical aspects in prescriptions by looking at the percentage of completeness of administrative and pharmaceutical aspects in prescriptions at the Wanaraja Garut Health Centre. This research is quantitative descriptive. The sampling method is random sampling which is calculated using the Slovin formula. The sample used was 308 prescription sheets in January 2021. Based on the results of the description of the completeness of prescriptions at the Wanaraja Garut Health Centre, of the 308 prescription sheets studied administratively, it was found that 60.90% were complete and 39.10% were incomplete, and studied pharmaceutically, it was found that 93.33% of the prescriptions were appropriate and 6.67% of the prescriptions were not appropriate. It can be concluded that the prescription sheet at the Wanaraja Garut Health Centre almost entirely meets the aspects of the completeness of the prescription in accordance with applicable laws and regulations, but it is still found that 11 out of 16 aspects of the completeness of the prescription do not contain information, namely the patient's age 2.27%, gender 30.51%, patient weight 98.51%, patient address 8.76%, doctor's name 47.7%, doctor's initials 64.28%, prescription date 3.57%, doctor's room or unit of origin 43.83%, doctor's SIP No. 0%, dosage form 11.3%, drug dosage 28.88%. This shows that the completeness of prescriptions at the Wanaraja Garut Health Centre is still incomplete, in writing prescriptions that trigger medication errors. It needs to be improved so that it meets the standards in accordance with applicable laws and regulations.
Co-Authors Aji Najihudin Anas Subarnas Ardi Rustamsyah Ardi Rustamsyah Ardi Rustamsyah Ardi Rustamsyah Asman Sadino Asman Sadino Dadang Muhammad Hasyim Devi Ratnasari Dewi, Risma Anugrah Diah Wardani Dindin Fahrudin Engkus Kusnadi Faizah Min Fadhlillah Faizatun Farid Perdana Firman Muharam Ghina Magfiroh Hanina Liddini Hanifa Hesti Kartini Hesti Renggana Hesti Renggana Hesti Renggana Hesti Renggana Hindun, Siti Isye Martiani Isye Martiani Jutti Levita K. Dewi Budiarti Mabarti, Azis Gandri Martiani, Isye Melinda Arismawati Mimin Kusmiyati Mimin Kusmiyati, Mimin Mina Pertiwi Muthia Dzakiyyah Nazi’ah, Milani Nopi Rantika Nurazizah, Siska Nurul Nurul Nurul Nurul Nurul Nurul Nurul Nyi Mekar Saptarini Perdana, Farid Puspitasari, Siva Puspitasari, Tien Ellita Endah Raden Aldizal Mahendra Rizkio Syamsudin Rahmi Ramdani, Hasbi Taobah Ratnasari, Devi Resta Nurseha Riki Rikardo Risa Susanti Risa Susanti Risa Susanti Ronny Lesmana Salma Nurin Fadilah Santi Yuliasari Siska Nurazizah Siti Nuraeni Sri Adi Sumiwi SRI RAHAYU Suwandi, Deden Winda Syswianti, Desy Taofik Rusdiana Yogi Rahman Nugraha Yunahara Farida Zahara Farhan Zakiah Nur Aeni