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All Journal MPI (Media Pharmaceutica Indonesiana) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JSFK (Jurnal Sains Farmasi & Klinis) Journal of Science Innovare FITOFARMAKA: Jurnal Ilmiah Farmasi Majalah Farmasetika AS-SHIHA: JURNAL KESEHATAN Journal Of Pharmacy
Lusi Indriani
Program Studi Farmasi FMIPAKes Universitas Muhammadiyah Riau
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : AS-SHIHA: JURNAL KESEHATAN

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Uji Aktivitas Antiinflamasi Ekstrak Etil Asetat Daun Tumbuhan Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr) pada Tikus Putih (Rattus norvegicus) Jantan Noveri Rahmawati; Dewi Gulyla Hari; Nurbaiti; Ayu Rahmawati; Nursyafni; Lusi Indriani; Tri Nova Lovena; Muhammad Arif; Nofri Hendri Sandi
As-Shiha: Jurnal Kesehatan Vol 3 No 1 (2023): As-Shiha: Jurnal Kesehatan
Publisher : Fakultas MIPA dan Kesehatan, Universitas Muhammadiyah Riau

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Abstract

Antiinflammatory activity of ethyl acetate extracts of the leaves of plant Akar Kaik-kaik Uncaria cordata (Lour.) Merr on white male rats. This research examined the quality of crude drugs and extracts ethyl acetate. It is intended to obtain raw materials which can ultimately ensure uniform pharmacologic effect. Antiinflammatory activity of the ethyl acetate extract were tested using the method of paw edema against white male rats. The research were 15 rats mile which divided into 5 groups. Negative control (Na CMC 1%), positive control (Na diklofenak dose 4,5 mg/kgBB) and extract group ethyl acetat with the dose 100, 200 and 400 mg/kgBB given orally. The volume measurement after subcutaneous injection caragen 1% performed with one hour interval for 5 hours assessing with pletysmometer and calculated the inhibition persen. The result of this study showed that the quality of crude drugs and extract ethyl acetate meet the specified requirements Indonesian Herbal Pharmacopoeia. Ethyl acetate extract has significant anti-inflammatory effects to the negative control at doses of 200 and 400 mg/kgBB while against the positive control did not differ significantly white male rats.
Co-Authors Aldryan Racka Pratama Alfahtiah Zurlina Almasyhuri Almasyhuri Amalul Ahli Azzikri Anton Bahtiar Arfian Eka Saputri Ayu Rahmawati Ayu Rahmawati Bina Lohita Sari Cantika Zaddana D Prasetyorini Devi Fitriyanti Dewi Gulyla Hari Dewi Gulyla Hari Dewi Oktavia Emy OKTAVIANI Erni Rustiani Haryanti Wulandari Ike Yulia Wiendarlina Juniarti Sri Maryati Sitinjak Jupersio Jupersio Mira Dewi Muhammad Arif Muhammad Raifal Khairi Mutiara Oktavia Sembiring Naufal Muharam Nurdin Nawwar Irfan Nisa Najwa Rokhmah Nofri Hendri Sandi Noveri Rahmawati Novita Sari Nur Shania Nurbaiti Nurdina Putri Nursyafni Nursyafni Retnosari Andrajati Sari Ramadhani Septia Andini Siti Niqmatun Jannah Tri Nova Lovena Tri Nova Lovena Zunnita, Oktaviana