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All Journal Jurnal Ilmiah Farmasi Farmasyifa Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Indah Sains dan Klinis Jurnal Pembaruan Kesehatan Indonesia
Adek Chan
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi

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Formulasi dan Uji Efektivitas Sabun Padat dari Ekstrak Etanol Daun Kopasanda (Chromolaena odorata L.) terhadap Bakteri Staphylococcus epidermidis Hafizhatul Abadi; Hanafis Sastra Winata; Adek Chan; Faadhilah Yusa Simbolon
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.444

Abstract

Siam Weed leaf plants contain high levels of flavonoids and tannins. These compounds provide antibacterial potential. This study aims to formulate solid soap dosage form of ethanol extract of Siam weed leaves and test the antibacterial activity of it against the growth of Staphylococcus epidermidis bacteria. This is experimental research. Making the extract phytochemical screening test. Evaluation of the dosage form was done by organoleptic tests, homogeneity, pH, foam height, moisture content, irritation, stability, and antibacterial activity tests using the well method. The results showed that solid bath soap dosage form from the ethanol extract of siam weed leaves could be formulated into soap dosage form which had a pH in the range of 9.2 – 9.8, high foam that was stable and did not cause irritation to the skin of volunteers and tested for antibacterial activity on bacteria. Staphylococcus epidermidis with a concentration of 10% 8.84 mm, 15% concentration 10.56 mm and 20% concentration 12.11 mm. The conclusion showed that solid soap dosage form of ethanol extract of Siam weed leaves (Chromolaena odorata L.) could be formulated and fulfilled the requirements after being evaluated and the antibacterial effectiveness of Staphylococcus epidermidis was the best at a concentration of 20% (strong).
Co-Authors Abadi, Hafizhatul Afrahul Padilah Siregar Agnes M. S. Saragi Anjur Falden Lingga Debi Meilani Ervina Syahfitri Lubis Faadhilah Yusa Simbolon Hendri Faisal Joko Wibowo Lukmanul Hakim Mandike Ginting Osy Devitania Samran, Samran Siti Fatimah Hanum Sumardi Suprianto Suprianto Vivi Eulis Diana Widya Atika Winata, Hanafis Sastra