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All Journal Karya Ilmiah S.1 Ilmu Keperawatan Jurnal Ilmu Keperawatan dan Kebidanan BAKTI BANUA : JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Science and Technology Research for Pharmacy Benzena Pharmaceutical Scientific Journal Science and Community Pharmacy Journal
Tunik Saptawati, Tunik
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Jurnal Farmasi dan Sains Indonesia (JFSI)

 1 
Formulasi Krim Fraksi Ekstrak Daun Kemangi (Ocimum sanctum L) Sebagai Antibakteri Terhadap Staphylococcus aureus dan Escherichia coli Saptawati, Tunik; Nurwidianingsih, Silvia; Girsang, Valentina; Aldila, Silvy
Jurnal Farmasi & Sains Indonesia Vol 7 No 2 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no2p112-120

Abstract

Dermatosis vesiculobullosa is a public health issue that frequently affects Indonesian society and even the world. Current treatment often involves topical application of a cream to the infected area, utilizing chemical substances and traditional medicine. One of the plants that has antibacterial properties is basil. This study determined the excellence of hexane fraction cream made from basil leaves to kill Staphylococcus aureus and Escherichia coli bacteria. This experimental study used the maceration method with 96% ethanol is used for extraction, while the liquid-liquid extraction method for fractionation. The well diffusion method examined the antibacterial activity. The concentration of the n-hexane fractions is 15%, 30%, and 45%. The physical characteristic tests of the cream include organoleptic, homogeneity, pH, spreadability, adhesion, and viscosity. The researcher conducted a one-way Anova statistical analysis using the post hoc Duncan test. Basil leaf cream with n-hexane fractions at 15%, 30%, and 45% concentrations has an antibacterial activity of 20.09 mm (very strong), 21.47 mm (very strong), and 22.43 mm (very strong) against Staphylococcus aureus. It has an antibacterial activity of 20.10 mm (very strong), 22.83 mm (very strong), and 23.76 mm. The cream formulations with 30% and 45% n-hexane fraction effective at stopping the growth of Staphylococcus aureus and Escherichia coli, with a significance value of 0.000 (p<0.05).
Potensi Anti Bakteri Hard Candy Ekstrak Asam Jawa (Tamarindus indica L.) dengan Minyak Sereh Wangi (Oleum Citronellae) Saptawati, Tunik; Handayani, Dwi Nurul; Gloria, Fransisca; Suwarni, Sri
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p98-103

Abstract

Tamarind and Sereh wangi (Citronellae winterianus Jowitt) are widely planted in Indonesia. Citronella oil is widely used as an anti-bacterial because of its secondary metabolite content. This study aims to determine the anti-bacterial potential of hard candy with active ingredients of tamarind extract and citronella oil. Tamarind fruit extract was prepared by maceration method using 96% ethanol solvent. Hard candy is made in 3 formulas with tamarind extract and citronella oil 0,1% (F1), citronella oil 0,2% (F2), and citronella oil 0,2% (F3). Antibacterial activity of hard candy examined using the disc diffusion method by measuring the diameter of the inhibition zone for the growth of Staphylococcus aureus and Escherichia coli bacteria. The result of the diameter of the inhibition zones F1, F2, and F3 for Escherichia coli were 4.25, 4.38, and 5.35 mm, respectively. The the diameter of the inhibition zones F1, F2, and F3 for Staphylococcus aureus were 2.30, 2.67 and 2.90 mm, respectively . It was showed that hard candy with active ingredients of tamarind extract and citronella oil was able to inhibit the growth of bacteria. The difference in the diameter of the inhibition zone between the formulas was analyzed using One Way Anova. The significance value is <0.05, so there is a significant difference in anti-bacterial activity between formulas. The concentration of citronella oil influence on antibacterial activity where the greater the concentration of citronella oil, the antibacterial activity to Staphylococcus aureus and Escherichia coli will increase. Keywords: Citronella oil, Tamarind, Hard Candy, Antibacterial.
PENGARUH TINGKAT PENGETAHUAN DENGAN IMPLEMENTASI PROGRAM DAGUSIBU OBAT ANTIBIOTIK PADA MASYARAKAT DI KABUPATEN JEPARA Arofa, Izanur; Suwarni, Sri; Indrasari, Ferika; Saptawati, Tunik; Gloria, Fransisca
Jurnal Farmasi & Sains Indonesia Vol 3 No 2 (2020)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

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Abstract

The relatively high use of antibiotics poses a threat to the emergence and spread of antibiotic resistance, there are now several findings that antibiotics have been used freely by the public. These antibiotics are purchased to treat symptoms of flu, fever, cough, sore throat, headache and other minor pain symptoms with a duration of use of less than five days. The level of education and knowledge of the community is one of the causes of this. The DAGUSIBU program (get, use, store and dispose) is the most important thing because knowledge is one way to be able to use medicine, store, get, and dispose properly. The purpose of the study was to determine the effect of knowledge with the implementation of the DAGUSIBU program for antibiotic drugs in the community in Jepara Regency from January to March 2020. This type of research is associative research with observational methods. Data were taken prospectively with a quantitative approach from an action research questionnaire. The sample used amounted to 500 respondents. The sampling technique used purposive sampling. Data were processed with chi square and Wilcoxon statistical tests using the SPSS program. The results showed that after the treatment of counseling with video and exposure to speakers and the provision of brochures on the dangers of antibiotic resistance, there was an influence on the level of knowledge with the implementation of the antibiotic drug DAGUSIBU program in Jepara Regency. as evidenced by the p value of 0.00
Co-Authors Aldila, Silvy Arofa, Izanur Asti Nuraeni Dayanti, Ema Elia Azani Girsang, Valentina Gloria, Fransisca Handayani, Dwi Nurul Indrasari, Ferika Kristiani, Monica Nita Fajaryanti, Nita Nurwidianingsih, Silvia Ovikariani Ovikariani, Ovikariani Rachma, Firstca Aulia Rahma, Firstca Aulia Sri Suwarni Tri Diana Puspita Rini Tri Nur Kristina Wijaya, Duma Aji Winarto -