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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin The Spirit of Society Journal : International Journal of Society Development and Engagement Jurnal Kesehatan Islam : Islamic Health Journal Medical and Health Science Journal Biomolecular and Health Science Journal Community Service Journal of Indonesia PREPOTIF : Jurnal Kesehatan Masyarakat Community Development Journal: Jurnal Pengabdian Masyarakat IJECS: Indonesian Journal of Empowerment and Community Services Prosiding Seminar Nasional Pengabdian Kepada Masyarakat
Meidyta Sinantryana Widyaswari, Meidyta Sinantryana
Universitas Nahdlatul Ulama Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

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Serum Level of Vitamin D (25[OH]D) in Patient with Atopic Dermatitis Meidyta Sinantryana Widyaswari; Iskandar Zulkarnain; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.857 KB) | DOI: 10.20473/bikk.V28.2.2016.88-95

Abstract

Background: Atopic Dermatitis (AD) is a chronic inflammatory relapsing skin disorder along with itchy sensation. Etiopathogenesis DA remains unclear, however in common are caused by impaired epidermal barrier function of the skin and immune system that tend to ensue infection. Vitamin D is an immunomodulator and plays an important role in the pathogenesis of DA through improving the integrity of skin barrier permeability, expression of antimicrobial peptide (AMP), which inhibit infection, and reduce inflammation. Deficiency of vitamin D may increase the development risk of DA lesion. Purpose: To evaluate the serum levels of vitamin D (25[OH]D) in patients with DA. Methods: A descriptive observational cross-sectional study, in 34 DA patients at Dermatology and Venereology Outpatient Clinic of Dr. Soetomo Hospital Surabaya. Subjects were enrolled through consecutive sampling, serum vitamin D levels were measured using enzyme-linked immunosorbent assay (ELISA) method. Results: Serum levels of vitamin D (25[OH]D) in DA patients was 22.72±14.55 ng/mL. Serum levels of vitamin D based on the severity DA: mild (30.86±22.66 ng/mL); moderate (20.42±10.13 ng/mL); and severe (18.84±8.22 ng/mL). Conclusion: Deficiency of vitamin D can occur in DA patient with low level of serum vitamin D (25[OH]D), but the relationship with the severity of DA remains to be done further research. Key words: atopic dermatitis, vitamin D (25[OH]D).
Co-Authors Agnovianto, Yuriske Basuki Widodo Bintarti, Tri Wahyuni Diah Mira Indramaya Fitriasari, Andikawati Guterres, Ribeilizho Carrol Lay Gloria Hans Lumintang, Hans Iskandar Zulkarnain Kamiran Kamiran Khamida Mahmudah Enny Widyaningrum Maria Ulfa Muhammad Taufiq Hidayat Muslichah Erma Widiana Noer Farakhin Noventi, Iis Nur Asiyah Putri, Winawati Eka Retna Gumilang Rinurwati Rinurwati Saputra, Dimas Bagus Dwi Soehardjoepri Soehardjoepri Suhud Wahyudi Supriyana, Herdiantri Troef Soemarno, Troef Wibowo, Bakti Widyaningrum, Mahmudah Enny Zakiyyatur Rizkiyyah Husin