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Journal : Jurnal Ilmu dan Teknologi Kesehatan

PENURUNAN ANGKA KUMAN SEBELUM DAN SESUDAH BERKUMUR DENGAN POVIDONE IODINE Lestari, Diah; Ananda, Liandry Dea Dwi; Setiawan, Heru; Prasetyorini, Tri
jitek Vol 11 No 2 (2024): Maret 2024
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v11i2.1449

Abstract

Povidone-iodine is considered to have the broadest spectrum of antimicrobial action compared with other common antiseptics. Based on the application protocol of commercial Povidone Iodine (PVP-I) mouthwash to support a healthy lifestyle, PVP-I is commonly used in concentrations of 1.0% with a contact time of 30 seconds. The higher the concentration of antiseptic, the smaller the time needed to kill microbes, but the maximum limit of concentration and contact time needs to be considered to minimize the toxicity effects to remain safe, effective, and efficient. This study aims to determine the comparison of germ numbers before and after gargling with povidone-iodine mouthwash based on variations in the concentration of 0.2%, 0.4%, 0.6%, 0.8%, and 1% with variations in contact time of 15 and 30 seconds. The method of this research was an actual experiment with a pre-post-test design. Based on the Non-Parametric Friedman test with a confidence level of 95% (α = 0,05), there is a significant difference between the germs number before and after gargling with PVP-I in every variation of concentration and contact time (p-value = 0.00). This study concludes that PVP-I 0.2% concentration variation with 15 seconds of contact time has been effective in decreasing the number of germs.
Profile of Serum Creatinine Levels with Creatinine Clearance Test (CCT) of Patients with Type 2 Diabetes Mellitus at Budhi Asih Hospital in 2021 Prasetyorini, Tri; Lestari, Diah; Anzalinna, Aliffiya; Suratun, Suratun
jitek Vol 10 No 1 (2022): September 2022
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i1.865

Abstract

Diabetes Mellitus (DM) is a group of metabolic diseases with hyperglycemia characteristics that can lead to kidney complications. One of them is Diabetic Nephropathy which is a complication of microvascular damage and its monitoring is done by checking serum creatinine and creatinine clearance test (CCT). The purpose of this study was to determine the relationship between serum creatinine levels and creatinine clearance test (CCT) in patients with type 2 DM. Perform a serum creatinine examination which is used as the basis for calculating CCT. From 53 data on type 2 DM patients who had high serum creatinine levels, 49 (92.5%) people, 51 (96.2%) people with low CCT levels. The results of Spearman's correlation statistical test showed a correlation between serum creatinine levels and CCT. The strength of the correlation is moderate, and the correlation shows a negative direction with a correlation coefficient (r) of -0.389. It can be concluded that the higher the serum creatinine level, the lower the CCT value, so DM patients must control blood glucose regularly in order to prevent a decrease in kidney function that can lead to complications.