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All Journal International Journal of Public Health Science (IJPHS) Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Acta Pharmaciae Indonesia : Acta Pharm Indo JCPS (Journal of Current Pharmaceutical Sciences) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Insan Farmasi Indonesia Bioscientist : Jurnal Ilmiah Biologi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Masyarakat Bangsa Jurnal Farmasi Indonesia Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan
Nashihah, Siti
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Journal : Acta Pharmaciae Indonesia : Acta Pharm Indo

 1 
Antibacterial activity of Cassia alata stems ethanol extract against Staphylococcus aureus Ahmad Mahdi Mar'ie; Irfan Zamzani; Siti Nashihah
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 10 No 1 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.1.5462

Abstract

Background: Cassia alata leaves, also known as petai cina or gelinggang in Indonesia, are commonly used to treat skin ailments. Objective: The purpose of this study is to test whether stem of C. alata has antibacterial activity against Staphylococcus aureus. Methods: C. alata stems were extracted using an ultrasound-assisted extraction method. For antibacterial activity, disc diffusion was used with extract concentrations of 25%, 50%, 75%, and 100%. Results: The inhibition zones of the ethanol extract of C. alata stems at 25%, 50%, and 75% concentrations were 17.6 mm, 21 mm, and 22.6 mm, respectively, with the highest inhibition zone at 100% concentration at 25 mm. Conclusion: The ethanolic extract of C. alata stems has a strong inhibitory effect on Staphylococcus aureus.
Antibacterial activity of Cassia alata stems ethanol extract against Staphylococcus aureus Mar'ie, Ahmad Mahdi; Zamzani, Irfan; Nashihah, Siti
Acta Pharmaciae Indonesia Vol 10 No 1 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.1.5462

Abstract

Background: Cassia alata leaves, also known as petai cina or gelinggang in Indonesia, are commonly used to treat skin ailments. Objective: The purpose of this study is to test whether stem of C. alata has antibacterial activity against Staphylococcus aureus. Methods: C. alata stems were extracted using an ultrasound-assisted extraction method. For antibacterial activity, disc diffusion was used with extract concentrations of 25%, 50%, 75%, and 100%. Results: The inhibition zones of the ethanol extract of C. alata stems at 25%, 50%, and 75% concentrations were 17.6 mm, 21 mm, and 22.6 mm, respectively, with the highest inhibition zone at 100% concentration at 25 mm. Conclusion: The ethanolic extract of C. alata stems has a strong inhibitory effect on Staphylococcus aureus.
Antibacterial activity of ethanol extract of limpasu (Baccaurea lanceolata) pericarpium with the ultrasound assisted extraction method against Propionibacterium acne Ulpah, Rusmili; Nashihah, Siti; Zamzani, Irfan
Acta Pharmaciae Indonesia Vol 11 No 1 (2023): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2023.11.1.6393

Abstract

Background: Acne, a prevalent skin condition, can arise from factors such as an unhealthy lifestyle, dietary habits, hormonal imbalances, and bacterial infections. Propionibacterium acnes is a notable bacterium responsible for acne. In South Borneo, the pericarpium of the limpasu plant (Baccaurea lanceolata) is traditionally used to treat acne. Objective: This study aims to scientifically validate the empirical antibacterial effects of limpasu pericarpium against Propionibacterium acnes, as reported by the communities in South Borneo. Methods: The ultrasound-assisted extraction (UAE) method was utilized to extract compounds from limpasu pericarpium. The antibacterial activity of the limpasu pericarpium extract was evaluated using the disc diffusion method at concentrations of 20%, 40%, 60%, 80%, and 100% w/v. Clindamycin served as the positive control, and 1% DMSO was the negative control. Results: The lowest concentration (20%) fell within the strong activity category, producing a clear zone diameter of 18.76 mm. Higher concentrations (40%, 60%, 80%, and 100%) demonstrated more potent antibacterial effects, with inhibition zones of 23.23 mm, 26.06 mm, 26.93 mm, and 27.33 mm, respectively. Notably, 60% to 100% concentrations exhibited greater inhibitory effects than the positive control, clindamycin, which had an inhibition zone of 25.23 mm. Conclusion: The study confirms the antibacterial properties of limpasu pericarpium against Propionibacterium acnes, supporting the traditional claims of its efficacy by the South Borneo communities.
Co-Authors Ahmad Mahdi Mar'ie Ahsana, Dina Andika Andika Andika Andika Andika Andika Atunnisa, Waro Damayanti, Indira Diah Safitri Dina Ahsana Dwi Utami Fajeriyati, Nurul Fitriah Fitriah Fitriani, Tiya Helma Novitasari Islan Nor Khairunnisa Khairunnisa Mahmudah Mahmudah Mar'ie, Ahmad Mahdi Maulana, Rafli Monica, Cahya Muhammad Yusron Maulana El-Yunusi Muliyati, Imas Murdi, Habib Basyanur Mustofa Ahda Nurkhasanah Mahfudh Ramadhanty, Dewi Alfisyah Rizka Mulya Miranti rizki rahmadi Rizqiannoor, Muhammad Sabilla, Giriani Ayu Siti Napisah Siti Rahmita Syifa Noorwina Ulpah, Rusmili Wandi, Halifah Risma Wardana, Kevin Febrian Waro Atunnisa Yulianita Pratiwi Indah Lestari Yulisa, Ika Zamzani, Irfan Zamzani, Irfan