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All Journal e-GIGI MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Journal of Indonesian Dental Association Jurnal Kreativitas PKM Jurnal Ilmu Kefarmasian Indonesia JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi Jurnal Material Kedokteran Gigi Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Community Empowerment J.Abdimas: Community Health Jurnal Abdi Masyarakat Indonesia JUARA: JURNAL WAHANA ABDIMAS SEJAHTERA Jurnal Kedokteran Gigi Terpadu Jurnal Abdimas Kesehatan Terpadu Sriwijaya Journal of Dentistry Kocenin Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat dan Riset Pendidikan
Florencia Livia Kurniawan
Universitas Trisakti
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Ilmu Kefarmasian Indonesia

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Characteristic and therapeutic effect of lemongrass leaf encapsulation with a different ratio of chitosan and NaTPP Kurniawan, Florencia Livia; Komariah, Komariah; Octarina, Octarina; Anggreani, Febry; Annisa, Fauziah Rahma; Nurlidar, Farah
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1570

Abstract

The lemongrass plant (Cymbopogon citratus) in Indonesia has great potential as a natural ingredient for medicines because it contains various compounds such as neral, citral, geranial acetate, flavonoids, and tannins. Previous research has demonstrated various pharmacological activities of kitchen lemongrass leaves, including antibacterial, antifungal, and anti-inflammatory properties. Encapsulation technology in the form of chitosan-NaTPP nanoparticles is used to maintain the activity of kitchen lemongrass leaf compounds. This research aims to determine the physical characteristics of the encapsulation of kitchen lemongrass leaf extract with several comparisons of chitosan and NaTPP by testing PSA (particle size analysis test), FTIR (functional group analysis test), viscosity, and stability, including pH and turbidity tests. Encapsulation with a 1:1 ratio of chitosan and NaTPP has a particle size of 524 nm and a PdI value of 0.481, classified as monodisperse (PdI <0.7). The pH value ranges from 6.46 to 7.30, and the viscosity value was 2.134–2.169 cP, which is still within mouthwash standards. The turbidity test showed stable encapsulation results. Therefore, encapsulation with a 1:1 ratio of chitosan and NaTPP is the most optimal choice and has potential for developing the therapeutic effect of mouthwash.
Co-Authors Achmad E. Z. Hasan Advita Azalia Andrietta, Gracia Anggreani, Febry Annisa Susilo, Fauziah Rahma Annisa, Fauziah Rahma Aribah, Nada Erica Armelia Widyarman Avila Johannes, Gerald Binartha, Ciptadhi Tri Oka Caesary Cloudya Panjaitan Carolina Marpaung Carolina Marpaung, Carolina Cloudya Panjaitan, Caesary Darma, Joshua Deviyanti Pratiwi Dewi Liliany Margaretta, Dewi Liliany Dewi Priandini, Dewi Dipankara, Jackson Dody Prayitno Dody Prayitno Dorothea Narendra Widiatmaja Eddy Eddy Eddy Eddy, Eddy Enrita Rahmadini Farah Nurlidar Fernando, Theodorus Aldo Fibryanto, Eko Fitria, Nada Hayuningtyas, Ria Aryani Indrayadi Gunardi, Indrayadi Iskandar, Gavin Benedict Isya Hanin JK, Febry Anggreani Johanna Halim, Rafhaela Kardinal, Yessica Puspita Komala, Olivia Nauli Komariah Komariah Komariah Laksmiastuti, Sri Lia Hapsari Andayani Lias, Steffy Lidwina, Naomi Louisa, Marie Martiningtiyas, Catur Rahayu Melaniwati Melaniwati Melaniwati, Melaniwati Meliani Miranti Putri Darmawanti Muhammad Ihsan Rizal Niko Falatehan Octarina Octarina Octarina Ozora, Rochelle Gita Perwira Lubis, Novo Putera Nova Azalia Raden Roro Asyurati Asia Rahmi Amtha Ratna Mira Yojana Ratnasari, Dina Rosalina Tjandrawinata Sastra Kusuma Widjaya Sastra Kusuma Widjaya Sheilla Megagupita Putri Marendra Siti Chandra Dwidjayanti SRI LESTARI Sri Lestari Sri Ratna Laksmiastuti Subrata, Aryadi Susanto, Shannon Winnie Suwartini, Tien Tansza Setiana Putri Thomas Aurelius Dharma Tiffany Hartono Tri Oka Binartha, Ciptadhi Trijani Suwandi Wiwiek Poedjiastuti Wulanasari, Selviana Yoana Winardi Yohana Yusra Yojana, Ratna Mira