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Journal : Medali Jurnal : Media Dental Intelektual

REGENERASI SEL LIGAMEN PERIODONTAL DENGAN KOLAGEN SISIK IKAN NILA (Oreochromis niloticus) Adhalin Fuku Handini; Rosa Pratiwi; Tahta Danifatis Sunnah
Jurnal Medali Vol 3, No 1 (2021): Media Dental Intelektual September 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v3i1.16767

Abstract

Background : Regeneration of periodontal ligament cells with tilapia scales collagen (Oreochromis niloticus) is one of the therapies that can be used in the field of periodontics. This review aims to explain the mechanism of periodontal ligament cell regeneration using tilapia scales (Oreochromis niloticus) collagen.Methods : Literature collection is done by selecting journals or articles through PubMed, NCBI, and Google Scholar based on keywords that match the author's criteria.Results : Regeneration of cells using collagen from tilapia scales can be used by using a bone graft technique because fish collagen contains calcium and phosphate that resembles human, namely hydroxyapatite (HAP). Fish scales are an alternative source of type I collagen and have the potential to be an alternative material for bone graft.Conclusions : Regeneration of periodontal ligament cells using tilapia scale collagen can be done using bone graft techniques. Fish scales have many benefits apart from having almost the same content as humans as well as materials that are still easy to obtain and a more economical price to use. The authors suggest that the researchers further conduct further research on the preparation of tilapia scales so that they can be applied in tissue engineering actions in the field of periodonsia.
THE DIFFERENCE IN COLOR CHANGE OF PREHEATED AND NON-PREHEATED NANOFILLER COMPOSITE RESIN AFTER IMMERSION IN NON-INSTANT AND INSTANT COFFEE Sri Ainur Astutik; Benni Benyamin; Rosa Pratiwi
Jurnal Medali Vol 4, No 2 (2022): Media Dental Intelektual September 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.4.2.123-129

Abstract

Background: One of the aesthetic issues in using composite resin is the color change. This study aimed to compare the color changes of preheated and non-preheated nanofiller composite resin soaked in non-instant coffee and instant coffee.Method: This study involved 24 round composite resins with a diameter of 12 mm and a thickness of 2 mm. The samples were divided into two groups (n=12); group I was prepared at 68°C and group II was prepared at room temperature. After curing, the samples were immersed in distilled water at 37°C for 24 hours before being measured with a UV-vis spectrophotometer. Each group was divided into two sub-groups (n=6), one soaked in non-instant coffee and the other in instant coffee for three days, and the final color was measured. The data was analyzed using two independent t-tests with a significance level of α =0.05.Result: Two independent t-tests revealed a significant difference between preheated and non-preheated nanofiller composite resins soaked in non-instant coffee (p<0.05), as well as a significant difference between preheated and non-preheated nanofiller composite resins soaked in instant coffee (p<0.05).Conclusion: The preheating was effective to improve the color stability of composite resin after immersion in non-instant coffee and instant coffee.
The Effect Of Soybean Extract Nanoemulgel (Glycine max (L.) Merill) On The Number Of Fibroblasts In The Healing Process Of Traumatc Ulcers (In Vivo Study on White Wistar Rats) Anjani, Fabela Artha; Feranisa, Anggun; Pratiwi, Rosa
Jurnal Medali Vol 7, No 1 (2025): Media Dental Intelektual February 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.7.1.1-11

Abstract

Background: Traumatic ulcers are a common oral lesioncharacterized by epithelial damage caused by trauma. They can healspontaneously within 7-10 days but may develop into chronic ulcers ifuntreated. Current treatments like hyaluronic acid gels are effective but costlyand can cause hypersensitivity reactions. This study aimed to analyze the effectof soybean extract (Glycine max (L.) Merill) formulated as a nanoemulgel onfibroblast proliferation during traumatic ulcer healing.Method: An in vivo study using male Wistar rats was conducted. Thirty ratswere divided into five groups: nanoemulgel soybean extract at concentrationsof 50%, 60%, and 70%, a positive control group (hyaluronic acid gel), and anegative control group (gel base). Treatments were applied daily for five days,after which fibroblast proliferation was evaluated histologically. Statisticalanalyses included Shapiro-Wilk, Levene's test, One-Way ANOVA, and Posthoc tests.Results: The 50% nanoemulgel soybean extract group showed the highestfibroblast count among treatment groups, indicating its potential in promotingulcer healing. However, hyaluronic acid gel outperformed other groups.Variability in nanoemulsion preparation likely influenced the fibroblast count.Conclusion: Nanoemulgel soybean extract demonstrates promising effects onfibroblast proliferation in traumatic ulcer healing, particularly at 50%concentration. Despite limitations in preparation, the results highlight itspotential as an alternative to conventional treatments. Further studies shouldoptimize the formulation and assess its toxicity.
EVALUATION OF PHYSICAL STABILITY OF BOESENBERGIA ROTUNDA EXTRACT FORMULATED IN NANOEMULGEL Pratiwi, Rosa; Sari, Rina Kartika; Amanda, Shania Dwika
Jurnal Medali Vol 7, No 1 (2025): Media Dental Intelektual February 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.7.1.36-44

Abstract

Background: Pinostrobin compounds from extracts of Boesenbergia rotunda have broad spectrum for bacteriostatic activity. The nanoemulgel preparation was chosen because it can penetrate well and quickly into the mucosa thereby increasing absorption. Physical stability tests need to be carried out to ensure the quality, safety and benefits of the gel meet the expected specifications and stability during storage. This study aims to determine which concentration has the most stable physical stability of pH and viscosity which were observed for 28 days.Method: 30 samples nanoemulgel preparation was used and then divided into 3 groups 45%, 67.5%, and 90%, Physical stability tests which is pH and viscosity tests was done for 28 days and stored in the Climatic Chamber with observation for every seven days. Data analysis used the One Way Repeated Measure Anova test followed by post hoc test was carried out. Result: The results showed most stable preparation was 45% and the least stable was 90% concentration. The mean values of the pH test 45% and 90% at baseline were 4.43 and 4.46 and at H+28 the values were 4.49 and 4.56. The average value of the viscosity test 45% and 90% at baseline was 1550 and 1210 and the values were 1600 and 1240 at h+28. Post hoc Wilcoxon test results for 45% concentration were p>0.05, indicating that there was no difference in pH and viscosity. It means pH value and viscosity of the 45% concentration were relatively constant from baseline to H+28.Conclusion: In conclusion, the results pH test and viscosity test of nanoemulgel preparations that were observed for 28 days showed that most stable preparation was concentration of 45%.
Comprehensive Analysis of Oral Health-Related Quality of Life (OHRQoL) in Periodontitis Patients: Evaluating the Impact of Non-Surgical and Surgical Periodontal Therapy Ratnawati, Irma Dewi; Rizky, Novi Sagita; Styaningrum, Yunita; Rahman, Erwid Fatchur; Aditya, Grahita; Putri, Nabella Devyanna; Pratiwi, Rosa
Jurnal Medali Vol 7, No 2 (2025): Media Dental Intelektual August 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.7.2.84-90

Abstract

Introduction: Periodontitis is a chronic inflammatory condition that affects the supporting structures of the teeth. Due to its often asymptomatic progression in early stages, timely diagnosis is frequently challenging.Objective: This study aimed to assess the impact of non-surgical and surgical periodontal treatments on the Oral Health-Related Quality of Life (OHRQoL) among individuals diagnosed with periodontitis.Methods: An observational analytic study with a cross-sectional design was conducted using a pre-test and post-test group approach. The study involved 100 patients aged 18–60 years who met predefined inclusion and exclusion criteria and underwent periodontal therapy either non-surgical or surgical at Sultan Agung Islamic Dental and Oral Hospital (RSIGM) between August and December 2024. The OHIP-14sp questionnaire was used to measure OHRQoL across seven domains using a Likert scale. Data were analyzed using descriptive statistics and paired t-tests to evaluate differences between pre- and post-treatment scores.Results: A marked reduction in OHIP-14sp scores was observed across all domains following treatment. The most pronounced improvements occurred in the domains of social disability (−46.2%) and functional limitation (−45.1%). Overall, the total OHIP-14sp score improved by 43.9%. All domains exhibited statistically significant differences between baseline and follow-up scores (p < 0.001). Conclusion: The findings indicated that both non-surgical and surgical periodontal therapies contributed significantly to enhancing patients’ quality of life by alleviating physical discomfort and improving psychological and social well-being.