Mothers with low knowledge have 3.069 times greater potential to have underweight toddlers than mothers with good knowledge. The prevalence of undernutrition in West Papua in 2021 was 10.8% while Fakfak Regency at 6.8% and Teluk Patipi District at 12.95%. This study was aimed to now the rationship between maternal knowledge and nutritional status of children. This cross-sectional study was conducted in 62 children aged 13-60 months. Nutritional status was determined using weight for height index while maternal knowledge was assessed using a questionnaire. Mothers with poor knowledge were 69.4%. Toddlers who experienced malnutrition were 33 toddlers (53.2%). The results of the bivariate test showed that there was a significant relationship between maternal knowledge about nutrition and nutritionsl status in toddlers (P<0.05). There was a relationship between maternal occupation and the nutritional status of toddlers (p=0.023). In contrast maternal age (p=0.784), maternal education (p=0.239), child age (p=0.078), and child gender (p=0.369) did not significantly relate to the nutritional status of toddlers. There was also the relationship between maternal knowledge and the nutritional status of toddlers in Teluk Patipi Sub-district, Fakfak Regency, West Papua.