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All Journal Journal of Pharmaceutical and Sciences.
Melati Yulia Kusumastuti
Program Studi Farmasi, Sarjana Farmasi, Sekolah Tinggi Ilmu Kesehatan Indah Medan, Medan, Sumatera Utara, Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Uji aktivitas antibakteri ekstrak etanol dan berbagai fraksi daun rimbang (Solanum torvum Swartz) terhadap Bakteri staphylococcus aureus. Devi Purnama Sari; Melati Yulia Kusumastuti; Safriana Safriana
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.281

Abstract

Traditional medicine is now seen as an opportunity for modern medicine because it is considered safer and believed to have complementary or synergistic effects, making traditional medicine beneficial. Rimbang leaves (Solanum torvum Swartz) are plants that can be utilized in traditional medicine. This study aims to determine whether ethanol extracts and various fractions of rimbang leaves have antibacterial activity against Staphylococcus aureus bacteria. Phytochemical screening results show that ethanol extract and ethyl acetate fraction of rimbang leaves contain secondary metabolites including alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides. The ethanol fraction consists of alkaloids, flavonoids, saponins, and glycosides, while it does not include steroids/triterpenoids. The n-hexane fraction only contains alkaloids and steroids/triterpenoids. The antibacterial activity against Staphylococcus aureus at a dose of 500 mg/ml shows that ethanol extract has an average inhibition zone of 14.83 mm, ethyl acetate fraction has an average of 21.67 mm, and ethanol fraction has an average inhibition zone diameter of 8.17 mm.
Co-Authors Devi Purnama Sari Safriana Safriana