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All Journal JURNAL PERTANIAN PRESISI (JOURNAL OF PRECISION AGRICULTURE) Soil REns Agrivet: Jurnal Ilmu-ilmu Pertanian dan Peternakan JAMAS: Jurnal Abdi Masyarakat Kapuas ROCE : Jurnal Pertanian Terapan
Muliani Muliani
Dept. Plantation Plant Cultivation, Politeknik Negeri Pontianak, [SINTA ID : 6775294]
Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Economics, Econometrics & Finance Engineering Law, Crime, Criminology & Criminal Justice Social Sciences Other

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Journal : ROCE : Jurnal Pertanian Terapan

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ANTIFUNGAL STUDY OF UNCARIA GAMBIR ROXB. (UGR) EXTRACT AGAINST GANODERMA SP. IN VITRO: STUDI ANTIFUNGI EKSTRAK UNCARIA GAMBIR ROXB. (UGR) TERHADAP GANODERMA SP. SECARA IN VITRO Nugroho, Rylo; Iskandar, Dodi; Rista Delyani; Danie Indra Yama; Muliani
ROCE : Jurnal Pertanian Terapan Vol. 2 No. 1 (2025): JPT ROCE 3, 2025
Publisher : PT. ROCE WISDOM ACEH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71275/roce.v2i1.52

Abstract

Ganoderma sp. is a pathogenic fungus that causes basal stem rot in oil palms, leading to significant yield losses. This study explores the antifungal potential of Uncaria gambir Roxb. extract against Ganoderma sp. using in silico and in vitro methods. In silico analysis from the KNApSAcK and PASS Online databases identified 18 secondary metabolites with probability activity (Pa) values ranging from 0.5 to 0.7, indicating high potential. Cinchonain Ia, an alkaloid with the highest Pa value of 0.638, has poor solubility. In vitro tests on U. gambir extract at various concentrations (0%, 1.5%, 2%, 2.5%, and 3%) showed that the extract was ineffective in inhibiting the growth of Ganoderma sp. Further research with variations in solvents, extraction methods, and formulations is needed to optimize the antifungal activity of this extract.
ANTIFUNGAL STUDY AGAINST CURVULARIA SP. FROM UNCARIAGAMBIR ROXB LEAF EXTRACT: STUDI ANTIFUNGAL TERHADAP CURVULARIA SP. DARI EKSTRAKDAUN UNCARIA GAMBIR ROXB Rexi Iswanto; Dodi Iskandar; Zaenal Mutaqin; Muliani; Danie Indra Yama
ROCE : Jurnal Pertanian Terapan Vol. 2 No. 1 (2025): JPT ROCE 3, 2025
Publisher : PT. ROCE WISDOM ACEH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71275/roce.v2i1.79

Abstract

Isomitrafoline and Speciophylline show the strongest general Anesthetic (92.2) compared to other ligands. This study aims to determine the effect of gambir leaf extract on the growth of Curvularia sp. fungus and the concentration of extract that can inhibit 50% of the growth of fungal colonies. The research method used was a Completely Randomized Design (CRD) with 4 variations of extract concentration (0%, 5%, 10%, and 15%), each repeated 6 times. The results showed that the highest concentration of gambir leaf extract in inhibiting fungal growth was at a concentration of 15%. LC 50% analysis revealed that the concentration required to achieve 50% inhibition was 118.16%, indicating that the effectiveness of the extract against Curvularia sp. fungus is low or less toxic
Co-Authors Achmad, Dwi Isyana Arbit, Muliani Danie Indra Yama Dodi Iskandar Dodi Iskandar, Dodi Dwi Isyana Achmad Fakhrudin, Jaini Ida Ayu Suci Jaini Fakhrudin MUHAMMAD ALI Muhammad Rizal MUHAMMAD RIZAL Muhammad Toasin Asha Mutaqin, Zaenal Nelson Fernando Siahaan Nugroho, Rylo Octoviani, Ninie Dwi Okto Ivansyah Purwandani, Ledy Ragil Putri Widyastuti Rexi Iswanto Rista Delyani Slamet Tarno Suharyani Amperawati Sutriyatna Sutriyatna Widyastuti, Ragil Putri Zaenal Mutaqin Zaenal Mutaqin