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Journal : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

Uji Senyawa Bioaktif Dan Toksisitas Limbah Cangkang Kerang Hijau (Pera Viridis) Suhaera Suhaera; Aprilya Sri Rachmayanti; Shinta Sari Dewi; St. Mursyidah; Dachriyanus Dachriyanus
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 3 (2021): NOVEMBER : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i3.2932

Abstract

Green mussels are organisms belonging to the class pelecypoda, this class has two bilaterally symmetric valve shells, these green mussels are referred to as bivalves, and are included in the soft-bodied marine biota (Mollusca). This study aims to determine the bioactive compounds and toxicity contained in the shells of green mussels (Perna viridis) which are processed seafood typical of the Riau Islands. Secondary metabolite screening tests include alkaloids, flavonoids, tannins, saponins, steroids and terpenoids as for toxicity tests using the BSLT (Brine Shrimp Lethality Test) method with shrimp larvae (Artemia salina Leach) test animals. The results of secondary metabolite screening on the test for alkaloids, flavonoids, tannins, steroids and terpenoids were declared negative while the saponin test was positive with the formation of stable foam. The results of the BSLT toxicity test (Brine Shrimp Lethality Test) with concentrations of 10 ppm, 100 ppm, and 1000 ppm obtained LC50 <1000 g/ml, which is 1127.28 ppm in the non-toxic category. In the sense that it is safe to be used as processed food.
Aktivitas Antibakteri Dan Antifungi Ekstrak Etanol Daun Nyireh (Xylocarpus Granatum J. Koenig) Suci Fitriani Sammulia; Suhaera Suhaera; Henny Rachdianti Tjahjono Suyarto; Arie Vonikartika; Yustika Sandey Margaretha
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 2 (2021): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i2.2933

Abstract

Nyireh plant (Xylocarpus granatum J. Koenig) is a mangrove plant that can usually grow in tidal areas, river embankments, and along rivers. This plant is believed to be a traditional medicine in dealing with diarrhea disorders, wound cleansers and sun protectors. This study aims to determine the antibacterial and antifungal activity of the ethanol extract of nyireh leaves against Pseudomonas aeruginosa, Sthapylococcus aureus and Candida albicans fungi. Nyireh leaf extract was prepared using the maceration method with 70% ethanol solvent. In testing the antibacterial and antifungal activity using the disc diffusion method with a concentration of 2%, 4%, 6%, positive control for bacteria (Tetracycline) positive control for fungi (Ketoconazole) and negative control (DMSO 5%). Research on the antibacterial and antifungal activity test of ethanol extract of nyireh leaves produced a strong inhibitory power at a concentration of 6%. In Pseudomonas aeruginosa bacteria concentration of 6% with an average concentration of 17.05 mm, Sthapylococcus aureus bacteria with an average concentration of 6% with an average of 22.95 mm and Candida albicans fungi at a concentration of 6% with an average of 11.88 mm. Potential as antibacterial and antifungal against the bacteria Pseudomonas aeruginosa, Sthapylococcus aureus and the fungus Candida albicans.