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All Journal Tadrib: Jurnal Pendidikan Agama Islam Majalah Farmaseutik PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Farmasi Innovative: Journal Of Social Science Research Jurnal Terapis Gigi dan Mulut Indonesian Journal of Pharmacology and Therapy
Puspita Sari, Ika
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Humanities Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Indonesian Journal of Pharmacology and Therapy

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Adverse effects of fentanyl/midazolam among patients of intensive care unit (ICU): a narrative review Septiyanti, Windy; Puspita Sari, Ika; Murti Andayani, Tri
Indonesian Journal of Pharmacology and Therapy Vol 5 No 2 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.11232

Abstract

Patients of intensive care unit (ICU) have a complicated condition due to disease, comorbid, and other risk factors. Some ICU patients need to get an invasive process to reduce pain, anxiety, and support their condition. During an invasive process, including mechanical ventilation which causes pain or anxiety, the patient is givensedative and analgesic agents to support the procedure and reduce the patient’s pain and anxiety. However, the use of fentanyl/midazolam has the potential to cause adverse effects, for instance, hypotension, hypoxia, and delirium in several ICU patients. Several risk factors that can lead to adverse effects are aging, obesity, underlying cardiac disease, and the amount of dosage. Therefore, it is essential to recognize the risk factors and monitor the use of fentanyl/midazolam to prevent the worsening condition of patients.
Co-Authors Arifin, Shokhibul Catharina Triwikatmani Danan, Danan Dian Anggraini, Truly Diana Sulistyawati, Ety Ibrahim, Mochammad Malik Kisworo Utami , Naning Luthfiananda, Berliana Muhammad Husaini Nisful Laila Nurdiah, Risa Indah Probosuseno Septiyanti, Windy Siti Salamah Tri Murti Andayani