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All Journal Manuju : Malahayati Nursing Journal Science Midwifery Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal WIDYA LAKSMI (Jurnal Pengabdian Kepada Masyarakat) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Kesehatan Amanah Cakrawala: Jurnal Pengabdian Masyarakat Global Jurnal Kabar Masyarakat Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia Health Community Service Prosiding Seminar Nasional COSMIC Kedokteran Kesejahteraan Bersama : Jurnal Pengabdian dan Keberlanjutan Masyarakat ALMURTADO: Journal of Social Innovation and Community Service
Jap, Ayleen Nathalie
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Journal : Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE)

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Association Of Anthropometric Measurement, Uric Acid, Vitamin D, Albumin, And Diabetes Mellitus With Frailty In The Elderly A Study At Bina Bhakti Elderly Home Santoso, Alexander Halim; Martin, Alfianto; Jap, Ayleen Nathalie; Lumintang, Valentino Gilbert; Alvianto, Fidelia
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4929

Abstract

Frailty is a common syndrome in older adults, marked by declining physiological reserves and increased vulnerability to adverse health outcomes. It impacts quality of life and links to higher morbidity, mortality, and healthcare needs. Identifying frailty markers early helps prevent or delay its onset. In Indonesia, frailty affects 10–20% of the elderly, with higher rates in rural areas and those over 75, driven by poor nutrition, chronic diseases, and limited healthcare access. This study explores these factors and their relationship with frailty in elderly residents of Bina Bhakti Elderly Home. This cross-sectional study analyzed anthropometric measurement, uric acid, vitamin D, albumin, and diabetes mellitus with frailty in 42 elderly residents, excluding those with cognitive impairments, acute illnesses, or psychiatric disorders. The analysis identified fasting blood glucose, HbA1c, and albumin as significant predictors of frailty, highlighting the importance of glucose regulation and nutritional status in frailty risk among the studied population. Fasting blood glucose, HbA1c, and albumin emerged as key predictors of frailty, highlighting the roles of glycemic control and nutritional health in reducing frailty risk. Lower fasting blood glucose and higher albumin levels were protective, while higher HbA1c increased vulnerability. Targeted interventions in these areas may effectively mitigate frailty risk.
Regulation of Fasting Blood Glucose, Insulin, and Homa-Ir in Relation to Malnutrition Among the Elderly: Mechanisms and Clinical Implications Kosasih, Robert; Sari, Triyana; Santoso, Alexander Halim; Jap, Ayleen Nathalie; Hartono, Vincent Aditya Budi; Syarifah, Andini Ghina
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.5057

Abstract

Malnutrition significantly disrupts metabolic processes like fasting blood glucose (FBG) regulation, insulin secretion, and insulin resistance (HOMA-IR), especially among the elderly. Aging amplifies these effects through declining β-cell function, reduced insulin sensitivity, and chronic inflammation, increasing the risk of type 2 diabetes and cardiovascular diseases. Globally, malnutrition affects 22% of the elderly, with prevalence reaching 28% in Indonesia due to food insecurity, limited healthcare access, and poor nutrition education. Malnutrition exacerbates glucose-insulin imbalances by causing muscle loss, increasing FBG levels, and inducing insulin resistance through chronic inflammation. Despite its impact, critical knowledge gaps remain, particularly in low- and middle-income countries like Indonesia. This study investigates how malnutrition affects FBG, insulin levels, and HOMA-IR in elderly individuals, focusing on mechanisms like inflammation and muscle loss to inform targeted interventions and improve metabolic health in resource-limited settings. This cross-sectional study evaluated fasting blood glucose, insulin, and HOMA-IR among 31 elderly participants at Panti Werdha Santa Anna. The study found no significant differences in fasting blood glucose, fasting insulin, HOMA-IR, or HbA1c levels across Mini Nutritional Assessment categories (normal, at risk, malnourished; p > 0.05). These results suggest no strong association between nutritional status and metabolic parameters, highlighting the need for further research with larger samples. This study finds no significant association between nutritional status and glycemic control in the elderly, suggesting malnutrition's indirect impact via mechanisms like inflammation and muscle loss. Comprehensive nutritional assessments remain essential to understanding its effects on metabolic health.
Co-Authors Agustina Alvianto, Fidelia Andersan, Jonathan Andria Priyana Averina, Friliesa Biromo, Anastasia Ratnawati Destra, Edwin Emilda, Emilda Ernawati Ernawati Fransisco, Melkior Michael Frisca Frisca Goh, Daniel Gracienne Gracienne Gunaidi, Farell Christian Hartono, Vincent Aditya Budi Herdiman, Alicia Kosasih, Robert Kurniawan, Joshua Lucius, Steven Hizkia Lumintang, Valentino Gilbert Martin, Alfianto Mashadi, Fladys Jashinta Moniaga, Catharina Sagita Nathaniel, Fernando Noer Saelan Tadjudin R Dewi, Fransisca Iriani Rayhan, Naufal Ruslim, Welly Hartono Santoso, Alexander Halim Sari, Triyana Satyanegara, William Gilbert Setia, Nicholas Shirly Gunawan Soebrata, Linginda Syarifah, Andini Ghina Tan, Sukmawati Tansil Teguh, Stanislas Kotska Marvel Mayello Warsito, Jonathan Hadi Wijaya, Dean Ascha Yohanes Firmansyah