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All Journal Nursing Care and Health Technology Journal (NCHAT) Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Sains Farmasi dan Kesehatan Galen: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Nerly Juli Pranita Simanjuntak
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Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Journal : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

 1 
Pengaruh Kombinasi Ekstrak Etanol Bawang Putih dan Kunyit terhadap Histopatologi Jantung dan Pankreas Tikus Diabetes Ana Fiske Hotmaida Simanjuntak; Nerly Juli Pranita Simanjuntak; Razoki, Razoki
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 2 (2025): Juli: Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i2.6703

Abstract

Diabetes mellitus (DM) is a chronic condition characterized by increased blood glucose levels that require long-term treatment to maintain stable blood sugar levels. Garlic and turmeric rhizomes are known to contain secondary metabolite compounds that have the potential to lower blood glucose levels. This study aims to see how the combination of garlic and turmeric rhizome extracts affects the histopathological picture of the pancreas of male white rats (DM). This study uses an experimental design method with a designposttest only control group involving 30 white male rats divided into five groups: Negative control (K-), positive control (K+), and three treatment groups with extract doses of 100mg/kgBW (F1), 200mg/kgBW (F2), and 300mg/kgBW (F3). The results showed the most significant decrease in blood glucose levels in the 300mg/kgBW group (F3), namely (105mg/kgBW). The histopathological picture of the pancreas showed severe damage in group F1 (75% had necrosis), and moderate damage (50% with necrosis) in F2 and F3. The combination of garlic extract and turmeric rhizome has the potential to reduce blood glucose levels and improve the histopathological picture of the pancreas in DM rats.
Evaluasi Drug Related Problems (DRPs) pada Pasien Penyakit Jantung di Poli Penyakit dalam RSU Royal Prima Marelan Innaya Sabrina Sirait; Razoki Razoki; Nerly Juli Pranita Simanjuntak
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 1 (2025): Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i1.6968

Abstract

Heart disease is the leading cause of death in Indonesia. The use of complex drugs in the treatment of heart disease increases the risk of Drug Related Problems (DRPs), especially due to the many comorbidities and drug interactions. The purpose of this study was to determine the incidence of Drug Related Problems (DRPs) in heart disease patients at the internal medicine clinic of Royal Prima Marelan Hospital. This study is a retrospective descriptive study of 50 outpatients diagnosed with heart disease in the period January-June 2024. Data obtained from medical records and patient prescriptions were analyzed to identify the types of DRPs based on the PCNE classification. Drug interactions were the most prevalent type of DRP (95,7%), with severity levels classified as moderate (80,5%), minor (12,6%), and major (4,4%). The most frequent interactions occurred between clopidogrel and omeprazole (major). Most patients were male (60%) and aged between 40-55 years (54%).
Co-Authors Ana Fiske Hotmaida Simanjuntak Astriani Natalia Astriani Natalia Br Ginting Caroline Theodora Christina Amelia Dhea Lovita Nasution Erida Novriani Fani Lolyta Br Sihotang Finna Piska Hikmad Elsi Enoni Harefa Innaya Sabrina Sirait Jennie Try Varian Laoli Jesiska Muaratan Marini Marini Nadia Raihana Novi Erviana Harahap Nuraisyah Amanda Razoki Razoki , Razoki Razoki Razoki Razoki, Razoki Rena Meutia Simran Kaur Tasya Melisa Br Purba Yova aditiatama