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All Journal Jurnal ABDIMAS MUTIARA JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL
Br Purba, Hana Ike Dameria
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL

 1 
UJI AKTIVITAS ANTIBAKTERI PADA MINYAK KELAPA MURNI (VCO) UNTUK MENGHAMBAT PERTUMBUHAN BAKTERI Streptococcus sanguinis Priltius, Natanael; Sinaga, Taruli Rohana; Br Purba, Hana Ike Dameria
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 1 No. 1 (2019): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Minyak kelapa murni atau virgin coconut oil (VCO) merupakan salah satu hasil olahan dari buah kelapa (Cocos nucífera). Minyak kelapa murni mengandung medium chain fatty acid (MCFA), yang terdiri atas asam laurat, asam kaprat, asam kaprilat dan asam miristat yang memiliki kemampuan antibakteri. Penelitian ini dimaksudkan untuk mengetahui daya hambat minyak kelapa murni terhadap pertumbuhan bakteri Streptococcus sanguinis.Penelitian ini adalah penelitian eksperimental murni. Penelitian eksperimen dengan rancangan posttest dengan kontrol grup ini menggunakan minyak kelapa murni yang diencerkan dengan pelarut Dimetil Sulfoksida(DMSO) yang juga digunakan sebagai kontrol negatif. Penelitian dilakukan dengan 3 variasi konsentrasi yang berbeda. Hasil penelitian menunjukkan bahwa ada aktivitas antibakteri pada setiap konsentrasi.Uji daya hambat dilakukan dengan metode difusi agar menggunakan kertas cakram. Perhitungan daya hambat dilakukan dengan menggunakan jangka sorong. Tampak bahwa minyak kelapa murni dengan konsentrasi 20%, 60%, dan 100% mampu menghambat pertumbuhan bakteri Streptococcus sanguis dengan rata-rata diameter zona hambat 8,3 mm, 8,83 mm, dan 10,63 mm. Disimpulkan bahwa minyak kelapa murni mampu menghambat pertumbuhan bakteri Streptococcus sanguinis dengan konsentrasi minimal 20%.
UJI AKTIVITAS DIURETIK INFUSA KUMIS KUCING (Orthosiphon stamineus Benth.) PADA TIKUS PUTIH JANTAN (Rattus Norvegicus) GALUR WISTAR Suharyanisa; Rosina Sitohang; Br purba, Hana Ike Dameria; Sulisty, Yenni
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 2 No. 1 (2020): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Diuretics are substances that can increase urinary output (diuresis) through direct action on the kidneys. Diuretics can also reduce electrolyte reabsorption in the renal tubules by involving active transport processes The cat's whiskers plant contains polymethoxylated flavonoid compounds, phenylpropanoids (caffeic acid derivatives), and terpenoids (especially diterpenes and triterpenes). IDKK was obtained from the infusion technique with distilled water and then the infusion was used on 25 diuretic rats which were divided into 5 groups. Group I (negative) Na-CMC 0.5%, group II (positive) Furosemide 3.6 mg/kgBB, and group III, IV, and V IDKK doses of 10, 20, and 40% were given orally. Rats were given aqua dest orally at a 15 ml/kg BW dose. Mice were placed in metabolic cages, then the physical examination of urine was carried out every 1 hour for 6 hours. The results showed that the IDKK with the best dose was 40%, which increased urine volume, affect urine pH, affect urine specific gravity, and affect the color of urine and the clarity of urine.
FORMULASI KRIM ANTI-AGING EKSTRAK ETANOL DAUN JELATANG (Urtica dioica L.) DENGAN PENAMBAHAN SARI LIDAH BUAYA (Aloe vera) Rialita Lifiani; Tampubolon, Manuppak Irianto; Br purba, Hana Ike Dameria; Oktaviana, Leni
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Urtica dioica L. or what is known as nettle is a perennial plant from the Urticaceae family. The leaves contain various medically important organic compounds and have antioxidant potential, including flavonoids. Antioxidants can be further utilized for the development of anti-aging in the form of topical dosage forms in the form of creams because of their easy use. This study aims to formulate and test the anti-aging effectiveness of nettle leaf ethanol extract cream preparations with the addition of aloe vera juice and to find out whether a cream containing ethanolic extract of nettle leaf (Urtica dioica L.) with the addition of aloe vera juice is able to provide an Anti-Aging effect on the skin. The method used was the experimental method. Nettle leaf was extracted by maceration using 96% ethanol solvent and concentrated with a rotary evaporator at 40°C, then the extract was made into cream preparations with a concentration variation of 0.2% (F1); 0.3% (F2); 0.4% (F3) and 0.5% (F4) with the addition of aloe vera juice with a constant concentration of 3% in each formula. As blank (F0), the cream base was used without the addition of extract. Evaluation of cream preparations included organoleptic test, homogeneity, emulsion type test, pH, stability test, viscosity, irritation, and anti-aging effectiveness test using a skin analyzer. Observations were made for 28 days by applying cream preparations behind the volunteers' ears. Results Nettle leaf ethanol extract with the addition of aloe vera extract can be formulated in a homogeneous cream dosage form, with a pH of 6.30 – 6.69, a viscosity of 16250-26750 cps, stable in storage for 28 days, and does not irritate the skin of volunteers. The conclusion obtained is that nettle leaf ethanol extract with the addition of aloe vera juice can be formulated in the form of a cream dosage form and a concentration of 0.5% shows the best anti-aging effectiveness.
Co-Authors Oktaviana, Leni Priltius, Natanael Rialita Lifiani Ritonga, Ahmad Hafizzulah Rosina Sitohang Sinaga, Taruli Rohana Suharyanisa Sulisty, Yenni Supartiningsih Tampubolon, Manuppak Irianto