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Kharizmatika, Kharizmatika
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Journal : MAHESA : Malahayati Health Student Journal

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Clinical Manifestations of the Gastrointestinal System in Patients with SARS-CoV-2 Infection Kharizmatika, Kharizmatika; Sukmana, Judya; Indrawati, Roostantia; Sulistio, Christian Bambang
MAHESA : Malahayati Health Student Journal Vol 4, No 10 (2024): Volume 4 Nomor 10 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i10.15845

Abstract

ABSTRACT SARS-CoV-2 infection was declared as a pandemic by the WHO since March 11, 2020, with confirmed cases increasing every year. SARS-CoV-2 is one of the varian of coronavirus that has a higher transmission rate, where it is transmitted through infected droplets. SARS-CoV-2 can manifest in the digestive tract. This descriptive study uses a literature study method. Diarrhea was a common symptom of gastrointestinal manifestations in COVID-19 patients. Apart from diarrhea, other symptoms are anorexia, nausea, vomiting and abdominal pain. Gender prevalence varies. The average age of patients exposed to COVID-19 was over 50 years with hypertension as the most common comorbidity. SARS-CoV-2 are associated with Gastrointestinal manifestations which binds to ACE2 on gastrointestinal epithelial cells. SARS-CoV-2 infection causes an imbalance in the gut microbiota that can trigger secondary infections and multiple organ disorders and affect the severity of COVID-19. Keywords: COVID-19, Gastrointestinal Symptoms, ACE2, Gut Microbiota, Gut-Lung Axis
Co-Authors Roostantia Indrawati, Roostantia Sukmana, Judya Sulistio, Christian Bambang