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All Journal Jurnal Ilmiah Pharmacy Jurnal Pharmacopoeia Indonesian Journal of Health Research and Development Bencoolen Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Sari, Rose Intan Perma
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Medical Sains : Jurnal Ilmiah Kefarmasian

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FORMULATION AND TESTING OF SOLID SOAP CONTAINING 96% ETHANOL EXTRACT OF PURSLANE (Portulaca oleracea L.) COMBINED WITH VIRGIN COCONUT OIL (VCO) AGAINST Staphylococcus aureus Sari, Rose Intan Perma; Rahmah, Anggi Apria Faradisya; Hermansyah, Oky; Rahmawati, Suci; Sipriyadi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1643

Abstract

Staphylococcus aureus is a pathogenic bacterium commonly associated with various infections. An initial step in preventing and addressing infections is the use of antibacterial soaps. The purslane extract can serve as an antibacterial agent that inhibits the growth of Staphylococcus aureus, while VCO offers additional protection through its antimicrobial properties and ability to maintain skin moisture. This study aimed to formulate a solid soap using 96% ethanol extract of purslane combined with VCO. Purslane powder was extracted using a maceration method. The physical properties of the soap were evaluated, including organoleptic evaluation, PH, homogeneity, foaming capacity, foam stability, and antibacterial activity against Staphylococcus aureus. Based on the results of the physical property evaluations, the solid soap met the required standards. The antibacterial effectiveness test showed inhibition zones for F1 at 3.21 ± 0,023 (weak category), F2 at 4,26 ± 0,102 (weak category), and F3 at 5,2 ± 0,070 (weak category). The results indicate that the purslane extract, in combination with varying amounts of VCO, can be formulated into solid soap that meets the physical property evaluation criteria and possesses antibacterial activity against the growth of Staphylococcus aureus.  Keywords: Solid Soap; Antibacterial; Purslane Plant; VCO; Staphylococcus aureus
Co-Authors : Samwilson Slamet, : Samwilson Agus Martono Arinda Nur Cahyani Azkiyah, Fadhilah Zayyin Betna Dewi Husna, Syarifatul Ikhsan Ikhsan Indah Sari, Puput Tri Marliza Marliza Masrijal, Camelia Dwi Putri Oktoviani, Oktoviani Oky Hermansyah Putri, Yona Harianti Rahmah, Anggi Apria Faradisya Rahmawati, Reza Reza Pertiwi ROBY SETIAWAN Sipriyadi Suci Rahmawati Versita, Riana Wirahmi, Nori