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All Journal Molecular and Cellular Biomedical Sciences (MCBS) Syntax Literate: Jurnal Ilmiah Indonesia Buletin Ilmiah Nagari Membangun Journal of Midwifery Majalah Kedokteran Andalas Contagion: Scientific Periodical Journal of Public Health and Coastal Health Andalas obstetrics and gynecology journal Science Midwifery Indonesian Journal of Global Health research Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat
Joserizal Serudji
Departement Of Obstetrics And Gynaecology, Faculty Of Medicine, Andalas Of University, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Andalas obstetrics and gynecology journal

 1 
Differences of Increased Bishop Scores Between Neutrophil Swab Vaginal ≤ 5 and > 5 in 41 Weeks of Pregnancy Induced With Misoprostol Boby Hartanto; Joserizal Serudji; Defrin Defrin
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.178-185.2021

Abstract

The incidence of labor induction with various indications was to increase. The key to successful labor induction is a ripe cervix. Research shows that the degree of cervical rippening as assessed by the Bishop score is influenced by the level of neutrophils contained in the cervical stroma which can be detected by performing a vaginal swab. Neutrophils will produce collagenase in the form of matrix metalloproteinase - 8 (MMPs - 8) which will degrade cervical collagen fibers, so that the cervix becomes soft and ripe. Misoprostol is the drug most widely used in labor induction today. Purpose: This study was to determine the difference in Bishop score increase between vaginal swab neutrophils ≤ 5 and > 5 in pregnancy ≥ 41 weeks induced by misoprostol.Keywords: Bishop score, neutrophil, vaginal swab, misoprostol
The Effect of Giving Virgin Coconut Oil (VCO) to Changes in Lauric Acid Levels in Breast Milk Ismul Sadly Putra; Joserizal Serudji
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.241-251.2021

Abstract

Breastmilk (ASI) is the best food produced by the breast glands, containing all the nutritional elements needed by infants aged 0-6 months. Apart from nutrients, breast milk also has other non-nutritional components that act as immune factors for babies. Babies who are not exclusively breastfed will be more susceptible to chronic diseases, such as heart disease, hypertension, and diabetes as adults and can suffer from malnutrition and obesity. Dietary intake significantly affects milk production. The mother's diet can affect the composition of her milk through several metabolic pathways, especially the concentration of fatty acids and vitamins that are soluble in fat and water, including vitamins A, C, B6, and B12. Lauric acid contained in breast milk can help your minor fight infection and increase immunity to protect from various diseases. Not only for the baby, but virgin coconut oil is also starting to be commonly used by dieters. Virgin coconut oil contains lauric acid CH3 (CH2) 10COOH 50% and caprylic acid CH3 (CH2) 6COOH 7%. Both of these acids are medium-chain saturated fatty acids that are quickly metabolized and have anti-microbial properties. The benefits of virgin coconut oil (VCO) are that it is beneficial for the health of the body, including being antibacterial, antiviral, anti-fungal, and natural anti-protozoa; helps relieve symptoms and reduces health risks associated with diabetes, helps protect against osteoporosis, helps prevent high blood pressure, helps prevent liver disease, keeps the heart and blood vessels healthy, helps prevent cancer, helps you lose weight, maintain stamina, maintain healthy skin and hair.Keywords: Breastmilk, Lauric Acid, VCO
DIFFERENCES IN PROTEASE ACTIVATED RECEPTOR-1 AND THROMBINE LEVELS IN PREECLAMPSIA AND NORMAL PREGNANCY Gistin Khusnul Khatimah; Joserizal Serudji; Vaulinne Basyir
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.27-34.2022

Abstract

Introduction: Preeclampsia is a condition caused by alterations in endothelial function during pregnancy. Changes in endothelial function result in an increase in coagulation and microvascular fibrin accumulation, which results in impaired placental perfusion. Thrombin, which converts fibrin to fibrinogen, as well as platelet activity, the fibrinolytic system, and anticoagulants, are all procoagulant circumstances in preeclampsia. Thrombin contributes to the pathogenesis of preeclampsia by increasing the expression of sFlt-1 thereby providing an antiangiogenic response. Protease Activated Receptor-1 (PAR-1) is a mediator of thrombin for coagulation and inflammation in preeclampsia. Inhibition of Protease Activated Receptor-1 expression in trophoblasts can enhance placental angiogenesis and vascular remodeling. Recently, only few studies have assessed the levels of Protease Activated Receptor -7 and thrombin in preeclampsia.Objective: To determine the difference in levels of Protease Activated Receptor-1 and thrombin in preeclampsia and normal pregnancyMethods: This study is observational with a cross-sectional comparative study design. Sampling was conducted from March 2020 to March 2021. A total of 66 patients were investigated, with 33 samples of preeclampsia and 33 samples of normal pregnancy. The independent sample T-test was used for statistical analysis.Results: The mean levels of Protease Activated Receptor-1 in the preeclampsia group were higher at 28.56 ± 7.68 ng/mL while normal pregnancy was 21.67 ± 6.92 ng/mL. The results of statistical tests showed that there was a significant difference in levels of Protease Activated Receptor-1 between the preeclampsia and normal pregnancy groups (p<0.05). The mean thrombin level in the preeclampsia group was higher at 72.23 ± 7.99 ng/mL, while in normal pregnancy it was 63.70 ± 8.92 ng/mL. The difference in thrombin levels between the preeclampsia and normal pregnancy groups was statistically significant (p<0.05).Conclusion: Preeclampsia was associated with greater levels of Protease Activated Receptor-1 and thrombin than normal pregnancy. There was a significant difference in the mean levels of Protease Activated Receptor-1 and thrombin between preeclampsia and normal pregnancy.Keywords: Thrombin, Protease Activated Receptor-1(PAR-1), Preeclampsia
Congenital Heart Defects: Risk Stratification for Pregnancy Joserizal Serudji
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.116-121.2022

Abstract

Major advances in medicinal and operative therapy on congenital heart defects (CHD) patients have led the majority of affected women survive to childbearing age. The risk of cardiovascular complications during pregnancy and peripartum depends on the type of the underlying defect, the extent and severity of residual haemodynamic lesions and comorbidities. Thuugh pregnancy is well tolerated in patients with CHD, but for some women with particularly high-risk lesions and poor functional class, pregnancy poses significant risk for cardiovascular complications, including premature death. As a result, preconception risk stratification and counseling are mandatory and should be done in all women of childbearing age with CHD. This will enable informed decision making for pregnancy savers.
Twin to Twin Transfusion Syndrome Joserizal Serudji
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.191-197.2022

Abstract

Introduction: Collateral arterial growth is an effective adaptation process to maintain blood supply in myocardial tissue distal to a coronary stenosis and in other vascular beds where feeding arteries are obstructed (1) . The drive for outgrowth and remodelling of arterial collaterals is an increased shear stress due to an enlarged blood flow occurring after the event of stenosis in a near by conduit artery. Remodelling includes increased growth of the diameter and length of the collateral, causing the characteristic tortuous or cork screw appearance (1) .Whilst collateral growth is generally beneficial, we will present evidence that arterial collateral out growth occurred in a monochorionic twin placenta where it jeopardised the pregnancy by causing the twin to twin transfusion syndrome (TTTS).Objective: to report a case of twin-to-twin transfusionCase Report: Reporting a case experienced and taken care in our Clinic Fetomaternal RS. Dr .M. Jamil Hospital. A 34 years old woman, gravida 2, para1, at 31 weeks and 6 days amenorrhea, because her pregnant uterus was too large for gestational Referral to tertiary center followed. At 32 weeks and 2 days amenorrhea biometry indicated estimated fetal weights of 1950 and 1450 g (Hadlock), oligohydramnios and polyhydramnios (amniotic fluid index:23cm. No structural anomaly of the heart was seen. No interventions, one course of corticosteroids were administered for fetal lung maturation. At 33 weeks a slight decrease in heart rate variability of the smaller twin was observed. A Caesarean section under spinal anesthesia was performed. Two girls were delivered of 1585 g and 2135 g and in good condition (Apgar scores 8 and 9 after 1 and 5 min in both girls). The monochorionic diamniotic placenta weighed 740 g. The cord of the recipient was centrally inserted and that of the donor velamentally. Placenta was born monochorion, diamnion.Conclusion: TTTS is caused due to unidirectional deep arteriovenous (AV) anastomoses with the superficial short comings. Hypovolemia, oliguria and oligohydramnion occurs in the donor fetus. Hypervolemia, polyuria and polyhydramnios occurs in the recipient fetus
Pregnancy with severe preeclampsia, acute kidney injury and nephrotic syndrome Joserizal Serudji; Haviz Yuad; Syntia Ambelina
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.330-337.2023

Abstract

Background: Preeclampsia is one of the main causes of maternal death every year. Preeclampsia can have badconsequences for both the mother and the fetus. Complications in the mother in the form of HELLP syndrome(Hemolysis, Elevated Liver Enzyme, Low Platelet), pulmonary edema, kidney disorders, bleeding, placentalabruption and even maternal death. Complications in infants can be premature birth, fetal distress, low birthweight or intra uterine fetal death (IUFD).Case Report: A 34 year old female patient was brought to the emergency room of Dr. M. Djamil Padang, sent tothe Batusangkar Private Hospital with complaints of shortness of breath which has been increasing when lyingdown. Physical examination found blood pressure 190/136. The patient was diagnosed with G2P1A0H1 gravidpreterm 25-26 weeks, PEB on maintenance dose MgSO4 regimen from outside, suspected nephrotic syndrome,CAP with hypoxemia, pleural effusion, AKI with metabolic acidosis, UTI, hyponatremia, hypoalbuminemia.Discussion: Preeclampsia, eclampsia and HELLP syndrome are serious and life-threatening conditions faced bypregnant women. Early diagnosis and prompt treatment via a multidisciplinary team in the ICU setting canprevent complications and reduce morbidity and mortality. The most common indications for intubation andmechanical ventilation are respiratory failure and hemodynamic instability. The cause of death in this patientwas multiple organ failure which was exacerbated by suspected nephrotic syndrome and suspected SLE.
CORRELATION OF MATERNAL SERUM 25 HYDROXY VITAMIN D WITH NEWBORN ANTHROPOMETRY Muhammad Iqbal; Yusrawati Yusrawati; Hudila Rifa Karmia; Joserizal Serudji
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.585-591.2024

Abstract

Vitamin D deficiency (VDD) is identified as a public health problem in many countries, and pregnant women have been identified as a high-risk group, among whom the prevalence of VDD ranges between 20 and 40%. Vitamin D deficiency causes essential health problems, not only in the mother but also in the baby, because the mother's vitamin D stores are the primary source of vitamin D for the fetus. During pregnancy, severe vitamin D deficiency in mothers has been associated with biochemical evidence of impaired bone homeostasis, congenital rickets, and bone fractures in newborns. This study aims to determine the correlation between umbilical cord blood 25(OH)D levels in term pregnancy and Neonatal anthropometry. This research is analytical research using a cross-sectional approach. The sample in this study amounted to 40 people. Data analysts use people tests. The results of this study obtained an average umbilical cord serum 25(OH)D level of 14.70 ± 4.93. There was no correlation between umbilical cord blood 25(OH)D levels in term pregnancy and neonate anthropometry (p>0.05). The average level of 25(OH)D is included in the insufficiency category. Therefore, it is necessary to increase vitamin D supplementation during pregnancy.
Co-Authors Adang Bachtiar Afriwardi Afriwardi Amir, Arni Arni Amir Arni Amir Bobby Indra Utama Boby Hartanto Defrin Defrin Denas Symond Desmawati Desmawati Fika Tri Anggraini Finny Fitry Yani Fuji Rahayu Henafi Gistin Husnul Gistin Khusnul Khatimah Hardisman Haviz Yuad Hirowati Ali Hudila Rifa Karmia Hudila Rifa Karmila Hudila Rifa Karmila Hudilla Rifa Karmia Hudilla Rifa Karmia Hudilla Rifa Karmia Hudilla Rifa Karmia Ilvira Ulpa Ismail Insani, Aldina Ayunda Iria Ningsih Busri Iria Ningsih Busri ismi mulya afti Ismul Sadly Putra Izmi Fadhillah Nasution Izmi Fadhillah Nasution Johanes C Mose Lisma Evareny Lisma Evareny Meilinda, Agus Miranie Safaringga Muhammad Iqbal Muhammad Iqbal Nabila Alfina Nelwati Nelwati Novita Br Ginting Munthe Novy Ratnasari Sinulingga Novy Ratnasari Sinulingga Nuzulia Irawati Rani Ashari Rani Ashari Rena Afri Ningsih Reyhan Julio azwan Reyhan Julio Azwan Rima Semiarty Rina Rina Rizanda Machmud Salma Afriliza Salma Afriliza Syntia Ambelina Vaulinne Basyir Vaulinne Basyir Vaulinne Basyir Vaulinne Basyir Vaulinne Basyir Yolanda Syahdia Yolanda Syahdia Yusmalia Hidayati Yusmalia Hidayati Yusrawati Yusrawati