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Alyanti, Tifani Kursya
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Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

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Journal : Jurnal Fitofarmaka Indonesia

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GC-MS Analysis of Ginger Rhizome with Various Extraction Methods Syarif, Rezki Amriati; Faradiba, Faradiba; Alyanti, Tifani Kursya; Savitri, Triana Aulia
Jurnal Fitofarmaka Indonesia Vol 11, No 3 (2024): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1105

Abstract

Ginger (Zingiber officinale) is a rhizome plant well-known as a spice and medicinal material. Either one of the bioactive components is an essential oil, which is efficacious in preventing and treating various diseases. This research aims to determine the percentage yield of extracts and GC-MS analysis of the percentage of the chemical content of essential oils of ginger with various extraction methods. Firstly, compounds from ginger rhizomes were extracted using maceration, ultrasonic, and distillation techniques, and the extracts were analyzed using GC-MS Spectrophotometer. The highest percentage extract yield from ultrasonic extraction was 21.29%, then maceration extraction was 6.26%, and distillation extraction was 5.00%. The GC-MS results showed that the secondary metabolite compounds from maceration, ultrasonics, and distillation contained zingiberol, zingiberin, shogaol, borneol, linalool, citral, geraniol, and E-citral. The zingiberol group of compounds was obtained with the highest percentage from ultrasonic extraction at 1.07%, then maceration extraction at 1.03%, and distillation extraction at 0.27%.
Pengaruh Variasi Metode Ekstraksi Jahe dan Serai terhadap Aktivitas Antiinflamasi pada Penghambatan Denaturasi Protein Faradiba, Faradiba; Syarif, Rezki Amriati Amriati; Khaira, A Tenri Mifta; Alyanti, Tifani Kursya
Jurnal Fitofarmaka Indonesia Vol 11, No 1 (2024): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v11i1.1184

Abstract

The content of secondary metabolites or chemical content in medicinal plants affects pharmacological activity. The level of chemical content is affected by the extraction method. Previous research has been conducted on the extraction of ginger and lemongrass using two methods, which include maceration and ultrasonic. The results obtained are differences in chemical content that have the potential to have anti-inflammatory activity. Ginger (Zingiber officinale) contains chemical compounds, including gingerol, shogaol, and zingeron. linalool, alpha-pinene, and sineol. Lemongrass (Cymbopogon citratus) contains citronellal, citronellol, geraniol, flavonoids, and tannins. The aim of this study was to compare the invitro anti-inflammatory activity of ginger and lemongrass extracts using two extraction methods: maceration and ultrasonic. The research method consists of two stages, i.e. extraction of samples using maceration and  ultrasonic methods. The second stage is testing the anti-inflammatory activity against BSA (Bovine Serum Albumin) denaturation of extracts from maceration and ultrasonic methods with the parameter of percentage value to be more than 20%. The results obtained from ginger and lemongrass extracts showed the percentage value of inhibition at concentrations of 10 µg/mL, 12.5 µg/mL, 17.5 µg/mL, and 20 µg/mL are all more than 20%. The ultrasonic extraction of ginger showed a more linear inhibition percentage than the results of maceration. Macerated lemongrass extract showed a more linear percentage inhibition than ultrasonic results.
Co-Authors Faradiba Faradiba Khaira, A Tenri Mifta Rezki Amriati Syarif, Rezki Amriati Savitri, Triana Aulia Syarif, Rezki Amriati Amriati