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Vina Purnamasari
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Medicine & Pharmacology

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Profil Penggunaan Obat Antihipertensi Pada Pasien Rawat Inap di RSUD La Temmamala Kabupaten Soppeng Akram Resa Nugraha; Hendra Herman; Vina Purnamasari
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Hypertension has become one of the deadly diseases in both Indonesia and the world. Hypertension (or high blood pressure) is defined as a condition when the blood pressure is above 140/90 mmHg. According to the profile of the Health Department of South Sulawesi Province in 2018, Soppeng Regency has the highest rate of people with hypertension at 98,79% with 4.997 from 5.058 patients. The purpose of this research is to describe the usage of anti-hypertension medicines to the patients at Latemmalala Regional Public Hospital, Soppeng Regency, in the period between June-December 2022. This research is considered a quantitative research with the descriptive method and observational research design, as well as the retrospective approach that begins with the documentary research taken from the patient’s medical records. The result shows that the characteristic rate of the patients according to the gender is mostly found on females, with 20 patients being confirmed (67,5%), for the ages between 60-69 years old, 15 patients are confirmed (46,9%), and the following disease that is also found on the patients with hypertension is the kidney failure, where there are 14 patients being confirmed (20%). The most used type of medicine is the calcium channel blocker (CCB), another medicine that is also often used is the 57 units of amlodiphine (37,5%), and the most-used combined medicines are 9 units of amlodiphine and furosemid (39,1%). According to the accuracy and the inaccuracy of the medical usage, the accuracy is 100% and the inaccuracy is 0%.
A LITERATUR REVIEW : AKTIVITAS IMUNOMODULATOR PADA TANAMAN HERBAL Dewi Yuliana; Dian Pratiwi Handayani; Vina Purnamasari
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Health problems that often occur in Indonesia are problems related to diseases caused by free radicals. The presence of free radicals can trigger damage to cells and can disrupt the body's immune system. The immune system can be enhanced or suppressed, one way is by administering immunomodulators. Several natural compounds have the ability to increase immune system activity, including flavonoids, curcumin, limonoids, vitamin C, vitamin E and catechins. Phenolic components such as flavonoids and polyphenols can improve the immune system by increasing Interleukin-12 (IL-12) and lymphocyte proliferation. Based on the many health problems that arise in Indonesia due to the presence of free radicals, the aim of the research is to conduct a literature review on the mechanism of action of herbal plants as immunomodulators and the methods used to determine the mechanism of action of natural immunomodulators. The method used to review this article is to carry out an online search process using several search engines such as PubMed, Scopus, ProQuest and Schoolar. Based on reference studies, several herbal plant extracts act as immunomodulators with different activities such as increasing the activity of Immunoglobulin M (IgM), reducing the number of leukocytes, stimulating the body's immunity with flavonoid content and increasing the ability of phagocytosis.
Co-Authors Akram Resa Nugraha Dewi Yuliana Dian Pratiwi Handayani Hendra Herman