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All Journal Indonesian Journal of Medicine Journal of Maternal and Child Health Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA
Endy Juli Anto
Universitas Methodist Indonesia
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health

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Journal : Jurnal Ilmu Kefarmasian Indonesia

 1 
Perbandingan Efi kasi dan Efek Samping Antara Albendazol, Albendazol-Levamisol dan Mebendazol-Levamisol Terhadap Infeksi Soil-Transmitted Helminths pada Anak Usia Sekolah Dasar Negeri Kabupaten Deli Serdang Endy Julianto
JURNAL ILMU KEFARMASIAN INDONESIA Vol 15 No 2 (2017): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (898.168 KB) | DOI: 10.35814/jifi.v15i2.511

Abstract

Intestinal worm infection in particular of Soil Transmitted Helminth is still a global problem with high prevalence on the tropic and subtropic regions including Indonesia especially in the rural community. Double Blind Randomized Trial that started from April to June 2015 in which the samples are collected from public elementary school children on the Deli Serdang Regency to compare the effectivity and side effect of STH infection treatment by using Albendazole 400 mg, Albendazole 400 mg-Levamisol 50 mg/100 mg, Mebendazole 500 mg-Levamisol 50 mg/100 mg. The samples of Albendazole, Albendazole-Levamisol and Mebendazole-Levamisol groups consist of 60 children in each group in which the ones that have STH infection are Ascariasis 92 children 51.11%, Trichuriasis 37 children 20.55%, and mixed infection 51 children 28.33%. In this research, researcher doesn’t found hookworm infection in any of the groups. From the result ofstool examination, researcher found 100% of cure rate for A. lumbricoides infection on all groups, cure rate of T. trichiura infection 66.7%, 94.7%, 92.3% for each Albendazole, Albendazole-Levamisol, and Mebendazole-Levamisol groups meanwhile cure rate for mixed infection are 28.6%, 85.7%, and 66.7% for each Albendazole, Albendazole-Levamisoland Mebendazole- Levamisol groups. For mild T.trichiura infection treatment with singledose of Albendazole-Levamisolgroup is better than both of Albendazole and Mebendazole- Levamisole groups (p=0.01). In this research, researcher found nausea and diarrhea as treatment of side effect and no signifi cant difference of side effect in all groups of treatment.
Co-Authors Agnes Imelda Manurung Alex M. Lumbanraja Alexander P. Marpaung Anjany, Larasaty Ardinata, Dedi - Caroline Koswara Chalil, M. Jalaluddin A. Depari, A. A. Dina Keumala Sari Dwi L. D. S. Siahaan Efbertias Sitorus Elizabeth Septianur Girsang Evirosa J. Simanjuntak Fadinie, Wulan Faskanita M. Nadapdap Fauzi, Tengku M. Fauzi, Tengku Muhammad Frengky S. Manullang Gani, Endang Haryanti Girsang, Elizabeth Septianur Hadyanto Lim Hakim, Enggrek Pelita Hamdi, Tasrif Helmida Gultom Hutapea, Kenal P. Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P. Ilyas, Syaffrudin Inda M. Sinaga Irfan Hamdani, Irfan Irina, Sinta Ivonne R. V. O Situmeang Ivonne Ruth Vitamaya Oishi Situmeang Jadeny Sinatra Jeffrey Jerry Tobing Jimmy Jimmy Jones Simatupang Juli Jamnasi Juliyanti Juliyanti Kembaren, Alfri Yoganta S. Laura P. S. Tambunan Lubis, Andriamuri P. Maludin Panjaitan Manik, Widya Dayanti Feronika Manullang, Frengky S. Manullang, Frenky Sorimuda Momot, Estela Salomina Nababan, Manaor Bismar Posman Natalie S., Karen Nazma, Diani Noviyanti, Berliana Noviyanti, Berliana Novrina Situmorang Panataria, Lince Romauli Panjaitan, Bintang Andika Pasaribu, Sumihar Maurist Rantos Pratiwi, Ade Dwi Putri Chairani Eyanoer, Putri Chairani Ria Oktavia Rimbun, Surjadi SARAGIH, MEYLIN KRISTINA Sari, Dina Keumala Sembiring, Budi Darmanta Sembiring, Mikael Siahaan, Dwi Lunarta D. S. Siahaan, Jekson Martiar Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sihombing, Parsaoran Sijabat, Kesia Silaen, Ester L. R. Silalahi, Veraci Silangit, Thomas Silitonga, Hendrika A Silitonga, Hendrika A Silitonga, Hendrika Adriana Silitonga, Hendrika Andriana Simanjuntak, Evirosa J. Simanjuntak, Harry C Simanjuntak, Harry C Simanjuntak, Jeremia Simanjuntak, Pantas Simatupang, Aditia Erick Cantona Simbolon, Boyke M. Sinaga, Inda M. Sinatra, Jadeny Sirait, Kilian Sitepu, John Frans Siti Normi, Siti Sitompul, Michael Sabatino Sitorus, Ragnar Oktavianus Situmeang, Ivonne Ruth Vitamaya Oishi Situmorang, Novrina Stephanie S., Kezia Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tanjung, Qodri F. Tarigan, Juliyanti Tarigan, Menang Bastanta Thomas Silangit Tiji, Widjaya Taufik Tobing, Paul S. M. L. Vivian Vivian Widjaya Taufik Tiji Wijaya, Mega YUNAFRI, ANDRI Zainumi, Cut M.