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Journal : Pharmademica: Jurnal Kefarmasian dan Gizi

Tingkat Kepatuhan Penggunaan Obat Antidiabetes Oral pada Pasien DM di Rumah Sakit Bantuan Rampal Malang Mayang Aditya Ayuning Siwi; Dzikrina Ilmanita; Merischa Shelviana Chahyaning Dias
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 1 No 2 (2022): Oktober - Maret
Publisher : LPPMKI - AKAFARMA AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.686 KB) | DOI: 10.54445/pharmademica.v1i2.15

Abstract

Diabetes Mellitus is a chronic condition that occurs due to the increased level of glucose in the blood. There are 10.70 million Indonesian people who have been diagnosed with diabetes, so Indonesia is ranked 7th among 10 countries with the highest number of diabetes sufferers. In long-term diseases such as diabetes mellitus, the compliance of drug use is one of the determinants for the success of therapy. This study aims to observe at the description of the use of oral antidiabetes drugs in DM patients at the Rampal Assistance Hospital, Malang. This research is descriptive research with a cross section approach. Data were collected using a Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire of 30 respondents. Data analysis was performed statistically, presented in the form of a percentage. Based on the results of the study, the level of compliance on the use of oral antidiabetes drugs at Rumkitban Rampal on April 2021 is 3 respondents (10%) of low compliance, 16 respondents (53.33%) of moderate compliance and 11 respondents (36.67%) of high compliance. Characteristics of patients that have a significant relationship with the level of compliance are the level of education, employment status, and the presence or absence of comorbidity. While the patient's age, gender, length of suffering and number of drugs used do not have a significant relationship with the level of compliance. Keywords: oral antidiabetic, diabetes mellitus, adherence level
Identifikasi Kandungan Asam Salisilat dalam Produk Krim Anti Jerawat di Pasar Tajinan Kabupaten Malang Fendi Yoga Wardana; Nurul Fadila; Mayang Aditya Ayuning Siwi
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 1 No 2 (2022): Oktober - Maret
Publisher : LPPMKI - AKAFARMA AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (542.429 KB) | DOI: 10.54445/pharmademica.v1i2.18

Abstract

Anti-acne cream is a type of cosmetics that is often used for skin care. Salicylic acid is often used as the active substance in this anti-acne cream. According to the Indonesian National Food and Drug Agency in 2019 on cosmetics, salicylic acid is allowed in cosmetics if it is not more than 2%. In this study, 6 types of anti-acne cream, from Tajinan Market, Malang Regency, were tested with the aim of studying the content of salicylic acid in anti-acne cream products. The test was performed qualitatively using a colour test with FeCl3 reagent (a positive reaction show a purple colour) and a thin layer chromatography (TLC) method using a solvent mixture of ethyl acetate;methanol;ammonia (8:1.90:0.10) as the mobile phase. Quantitative determination of the content was performed using UV-Vis spectrophotometry. The qualitative test with the colour test indicates that samples A and E are positive for containing salicylic acid. The results of the thin layer chromatography (TLC) test indicates that sample A is positive for containing salicylic acid with an Rf value of 0.66, which is the same as the comparison standard. The quantitative test with UV-Vis spectrophotometry indicates that the salicylic acid content in sample A is 2.516%, sample D is 1,400%, and sample E is 1.646%. In conclusion, only cream of sample A do not meet the requirements of the Indonesian National Food and Drug Agency because it has a salicylic acid content of more than 2%.