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Journal : Annales Bogorienses

Antidiabetic, Antioxidants and Antibacterial Activities of Lactic Acid Bacteria (LAB) from Masin (Fermented Sauce from Sumbawa, West Nusa Tenggara, Indonesia) Manguntungi, Baso; Vanggy, Leggina Rezzy; Fidien, Khadijah Alliya Fidien; Saputri, Dinar Suksmayu Saputri; Mustopa, Apon Zaenal; Ekawati, Nurlaili; Nurfatwa, Maritsa; Prastyowati, Anika; Irawan, Shasmita
Annales Bogorienses Vol. 24 No. 1 (2020): Annales Bogorienses
Publisher : BRIN

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Abstract

The study aimed to determine the effectiveness of metabolites from Lactic Acid Bacteria (LAB) derived Masin (fermented sauce from Sumbawa) as antioxidant, antidiabetic, and antibacterial compounds. The LAB isolates were isolated from various strains of Staphylococcus piscifermentan which consisted of Staphylococcus piscifermentans strain CIP103958 (code: 2), strain BULST54 (code: 17), strain SK03 (code: 11), strain ATCC 51136 (code: 34), strain PCM 2409 (code: 28) and strain PU-87 (code: 5). The Metabolites of LAB were analyzed by the bioprospecting test to indicate antidiabetic, antioxidant and antibacterial activities. The isolate (Code: 5) at 500 ug/ml showed the most effective antioxidant activity up to 71%. The isolate (code: 28), at 300 ug/ml revealed to have the most antidiabetic activity up to 43 %. The isolate (code: 2) showed moderate antibacterial activity with the inhibition zone of 5.59 mm. The results of the antidiabetic, antioxidant and antibacterial activity showed that the secondary metabolites produced by LAB from the Masin have broad activities as an antidiabetic, antioxidant and antibacterial.
Antioxidant, Antibacterial, and Antidiabetic Activities of Roselle (Hibiscus sabdariffa) Extracts Suharli, Lili; Manguntungi, Baso; Azis, Andi Asmawati; Mustopa, Apon Zaenal; Meilina, Lita; Pandayu, Iga Firmansyah; Vanggy, Leggina Rezzy; Irawan, Shasmita
Annales Bogorienses Vol. 25 No. 2 (2021): Annales Bogorienses
Publisher : BRIN

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Abstract

Hibiscus sabdariffa L., also referred to as roselle, is commonly utilized in the pharmaceutical and food industries. Roselle contains bioactive compounds such as phenolics, alkaloids, tannins, flavonoids, saponins, and organic acids, which have pharmacological properties, such as antioxidant, antibacterial, immune booster, antidiabetic, anti-inflammatory, and anti-hypertensive properties. There are many studies regarding the pharmacological activities of roselle extract and its applications. However, there has been no research to study the effectiveness of the solvent in testing roselle petal extracts against antibacterial, antioxidant, and antidiabetic activities, simultaneously. This research used two kinds of polar solvents, dH2O and ethanol, with various concentrations for antibacterial activity test by five pathogenic bacteria, for antioxidant test by the DPPH method, and for antidiabetic test by the alpha-glucosidase inhibition method. The result showed that the ethanol extract of roselle had higher antibacterial activity compare to the roselle water extract. Antioxidant activity of roselle ethanol extract at 20% concentration had the highest activity 69.75 ± 0.002%; while, the 100% concentration of roselle water extract had the highest antioxidant activity 138.73 ± 0.013%. antidiabetic activity of roselle ethanol and water extract at 100% concentration had the highest activity 1,195.44 ± 0.007% and 1,552.49 ± 0.069%, respectively.
Co-Authors A. Masniawati Adha Ardinata, Rian Afgani, Chairul Anam Ai Hertati, Ai Akmaliyah, Rizna Alfiana Amani, Febriyanti Nur Amrullah, Shafwan Andi Asmawati Azis Andi Dewi Rizka Ainulia Makerra Anika Prastyowati Anika Prastyowati, Anika Anita Ervina Anja Meryandini Apon Zaenal Mustopa Apon Zaenal Mustopa Apon Zaenal Mustopa Ariandi Ariandi Ariandi, Ariandi Arlinda Puspita Sari Asia Arifin Asmawati, Rian Adha Ardinata Muhammad Al Azhar Bugi Ratno Budiarto Chaidir, Riri Rimbun Anggih Chairunnisa, Sheila Chihombori, Tatenda Calvin Dahliah Depparinding, Rekianto Dwi Ratna Sari Ekawati, Nurlaili Endang Saepudin Eva Johannes Eva Johannes Fadhil Zil Ikram Fahri Sinulingga Fatimah Fidien, Khadijah Alliya Fidien Hasgun Iman Rusmana Intan Dwi Pratiwi Irawan, Herman Irawan, Shasmita Irlan izzul islam Jendri Mamangkey Jumriani, Siti Khadijah Alliya Fidien Khotibul Umam Kurniawan Eka Putra Tegar Aprilian1 Kus Dianawati Kustiariyah Tarman La Ode Fitradiansyah Leggina Rezzy Vanggy Leggina Rezzy Vanggy Leggina Rezzy Vanggy Lukman Azis Magdalena Litaay Maritsa Nurfatwa Masni Masni Meilina, Lita Mietra Anggara Mohammad Rofiqi Muh. Chaerul Anwar Muhammad Abdi Mahesa Muhammad Fajri Al-Fateeh Muhammad Ilham S Muhammad Rajib Muhammad Rizaldi Trias Jaya Putra Nurdin Muhammad Rofiq Muis, Nurmuliayanti Musdalipah Mustika Tuwo, Mustika Mutiara, Ilma Nairfana, Ihlana Naning Sufiyanti Nur Hilal A. Syahrir Nurdin, Rizaldi Nurfatwa, Maritsa Nurlaili Ekawati Nurmuliayanti Muis Nurmuliayanti, Nurmuliayanti Nurul Amilia Pandayu, Iga Firmansyah Putra, Kurniawan Eka Rahmadinah, Nurul Afifah Rahman, Auliyah Ramlah Ramlah Ramlah Refli, Redoyan Rian Adha Ardinata Muhammad Al Azhar Asmawati Riana Anggraeny Ridwan Rifqiyah Nur Umami, Rifqiyah Nur Rika Indri Astuti Robby Erlangga Ruth Dameria Haloho Sama, Yusuf Saputri, Dinar Suksmayu Saputri, Dinar Suksmayu Saputri Shasmita Irawan Sri Wahyuni Suharli, Lili Sulastri, Ani Syamsul Arifin Tegar Aprilian Tiara Fitri Erinanda Trinugroho, Joko P Ulfa Febiana Whatin Vanggy, Leggina Rezzy Wahyullah Wahyullah Widya Dwi Kusuma Yulianti Yulianti Yusran Yusran Zainal