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ISM (Intisari Sains Medis) : Jurnal Kedokteran

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Published by Universitas Udayana

ISSN : 25033638 EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.

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Articles 68 Documents

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Search results for , issue "Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)" : 68 Documents clear

Teledermatology for managing COVID-19 patients with cutaneous manifestation: case series study in a rural primary hospital Dedianto Hidajat; Hamsu Kadriyan; Slamet Tjahjono
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/ism.v13i1.1224

Background: To provide information and experience about using WhatsApp as a tool in teledermatology to facilitate the identification, treatment, and follow-up of skin problems in COVID-19 patients hospitalized at one of a rural primary hospital located in Indonesia.Methods: All COVID-19 patients with the dermatology manifestation were included in this study. All symptoms and signs of cutaneous manifestation and teledermatology consultation aspect were recorded.Results: There were 7 cases confirmed with skin manifestation (0.9%) from 783 hospitalized patients from March 2020 to June 2021. There were 5 males and 2 females. The age range was 50 - 66 years old. Pruritus is the main complaint, followed by pain and swelling. The cutaneous lesions were mainly maculopapular, followed by papulovesicular and edematous eruptions. The onset of the lesions appeared between the 2nd and 12th day during hospitalization. Both patients and physicians feel comfortable using this platform in consultation.Conclusion: There are advantages and disadvantages to utilizing this concept in the medicolegal aspects, including non-uniform audio-visual quality and also ethical and privacy issues, especially in a rural area.

Prevalensi nyeri bahu pada peserta klub kebugaran F.X Juanda Setiajaya
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Background: Shoulder pain is pain that arises in the shoulder area caused by structural disorders of the shoulder such as muscles, bones, ligaments or tendons. Shoulder pain is often made worse by exercise. Nowadays many people join fitness clubs to exercise, one of the exercises is lifting weights. Certain movements, such as the bench press, pectoral fly, and overhead press, are weight-bearing exercises that put a lot of weight on the shoulders and can cause shoulder pain. Factors of age, gender and level of physical activity also play a role in the occurrence of shoulder pain in a person. This study was conducted to determine the prevalence of shoulder pain in fitness club participants and to describe the influencing factors. Methods: This study is a cross-sectional survey from July to September 2016. The respondents in this study were the fitness club participants at the Golf Graha Family and Country Club, Surabaya as many as 73 people using purposive sampling technique. The variables in this study consisted of gender, age, level of physical activity, exercise patterns, and shoulder pain. The data obtained will be presented descriptively. Results: There were 73 samples involved in this study. The mean age was 28.48±10.362, of which 53.4% were in the 17-25 year old group. Female gender, age group 17-25 years, weight training pattern, and moderate activity were found to have the highest percentage of shoulder pain. Conclusion: In this study, respondents who performed weightlifting exercises that supported the shoulders were also more prone to experiencing shoulder pain. Latar belakang: Nyeri bahu adalah rasa sakit yang timbul pada daerah bahu disebabkan oleh gangguan struktur bahu seperti otot, tulang, ligamen atau tendon. Nyeri bahu sering diperburuk oleh olahraga. Saat ini banyak orang yang mengikuti klub kebugaran untuk berolahraga, salah satu latihannya adalah angkat beban. Gerakan tertentu seperti bench press, pectoral fly, dan overhead press merupakan latihan angkat beban yang memberi tumpuan yang berat pada bahu dan berisiko menimbulkan nyeri bahu. Faktor usia, jenis kelamin dan tingkat aktifitas fisik juga berperan dalam terjadinya nyeri bahu pada seseorang. Penelitian ini dilakukan untuk mengetahui prevalensi nyeri bahu pada peserta klub kebugaran serta menggambarkan faktor yang berpengaruh. Metode: Penelitian ini merupakan penelitian survei potong lintang pada bulan Juli hingga September 2016. Responden pada penelitian ini adalah peserta klub kebugaran di Golf Graha Family and Country Club, Surabaya sebanyak 73 orang dengan teknik purposive sampling. Variabel dalam penelitian ini terdiri dari jenis kelamin, usia, tingkat aktivitas fisik, pola latihan, dan nyeri bahu. Data yang didapat akan disajikan secara deskriptif. Hasil: Terdapat 73 sampel yang terlibat dalam penelitian ini. Rata-rata usia 28,48±10,362 dimana 53,4% dalam rentang kelompok 17 – 25 tahun. Jenis kelamin perempuan, kelompok usia 17 – 25 tahun, pola latihan angkat beban, dan aktivitas sedang ditemukan memiliki persentase nyeri bahu tertinggi. Kesimpulan: Pada penelitian ini responden yang melakukan latihan angkat beban yang memberi tumpuhan pada bahu juga lebih rentan untuk mengalami nyeri bahu.

Incontinentia pigmenti in neonate: a case report Putu Gde Hari Wangsa; Luh Made Mas Rusyati; I Gusti Ayu Agung Dwi Karmila; Ni Luh Putu Ratih Vibriyanti Karna; Ketut Wida Komalasari; Made Hermina Laksmi
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/ism.v13i1.1227

Background: Incontinentia pigmenti (IP) is a rare X-linked dominant inherited genodermatosis that occurs almost in females and is usually accompanied by other ectodermal tissue diseases such as the central nervous system, eyes, hair, nails, teeth and skeletal system. This case report aims to enhance understanding of incontinentia pigmenti and provide appropriate treatment to patients and proper education to families. Case report: A 3-days-od baby girl was consulted by the Pediatric department with complaints of blisters and erythematous rashes on almost her entire body with the Blaschko line distribution. The nails on the right and left big toes appeared inward. No history of fever and seizure. No family had similar complaints. There were no eye and nerve abnormalities involved. She treated with hydrocortisone 1% cream every 12 hours on erythematous papules and vesicles, open compresses with 0.9% NaCl every 8 hours for 10-15 minutes on lesions with yellowish crusts. Thus, the patient diagnosed with incontinentia pigmenti. Conclusion: The diagnosis of incontinentia pigmenti is based on history and physical examination. This case is very rare, so the family needs to understand the course of this disease. Appropriate management and education can prevent secondary infection.

Bibir sumbing dengan penyakit jantung bawaan: laporan kasus Florencia Christina Sindhu; Peter Prayogo Hsieh; Anak Agung Made Sucipta
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Background: Congenital malformations contribute to neonates’ mortality. Cleft lip is one of the most common congenital malformations. It’s usually accompanied by other organs’ malformations, such as cardiovascular system. This case report aims to increase the awareness about other congenital malformations which can accompany cleft lip. Case: Baby girl born by sectio caesarea from 39 weeks of pregnancy with premature rupture of membrane. Antenatal USG examination showed that baby was in breech position and suspect congenital malformation. She cried immediately after delivery and had good muscle tone. On examinations, she weighed 2.200 grams, her length was 46 cm, and her head circumference was 30 cm. Her vital signs showed heart rate 152 beats/minute, respiratory rate 50 times/minute, temperature 36.8oC, and SpO2 98%. A cleft on right nose, lip, and palate was found. No abnormalities in thorax, abdomen, vertebra, and extremities examinations. Echocardiography examination showed suspect PFO, mild tricuspid regurgitation, and trivial mitral regurgitation. Her SpO2 dropped to 90% while in perinatology room so she received 0.5-1 liter/minute oxygen supplementation using nasal cannula. On the 7th day, we found secrets on both eyes. Gram examination was done and it tested negative. She received levofloxacin eye drop every 2 hours on both eyes. She was breastfed using specially-designed pacifier. On the 10th day, she was discharged in a good condition. Conclusion: Cleft lip is usually accompanied by other organs’ malformations, such as cardiovascular system. Comprehensive examinations must be done for every baby born with cleft lip. Latar Belakang: Malformasi kongenital berkontribusi terhadap angka mortalitas bayi. Bibir sumbing merupakan kelainan kongenital yang sering terjadi dan biasanya disertai malformasi organ lain, seperti sistem kardiovaskular. Penulisan laporan kasus ini bertujuan meningkatkan kewaspadaan terhadap kelainan bawaan yang mungkin menyertai bibir sumbing. Kasus: Bayi perempuan dilahirkan secara sectio caesarea dari kehamilan berusia 39 minggu 6 hari yang disertai ketuban pecah dini. Pemeriksaan USG saat kehamilan menunjukkan bayi letak sungsang dan curiga kelainan kongenital. Ketika lahir, bayi segera menangis dan tonus kuat sehingga dilakukan perawatan rutin. Pada pemeriksaan, bayi memiliki berat lahir 2.200 gram, panjang badan 46 cm, dan lingkar kepala 30 cm. Tanda vital menunjukkan denyut jantung 152 kali/menit, laju pernafasan 50 kali/menit, suhu 36.8oC, dan SpO2 98%. Pada pemeriksaan kepala ditemukan celah pada hidung, bibir, dan langit-langit mulut kanan serta tidak ditemukan kelainan pada thoraks, abdomen, vertebra, dan ekstremitas. Pemeriksaan echocardiography menunjukkan suspek PFO, mild tricuspid regurgitation, dan trivial mitral regurgitation. Saat perawatan di ruang perinatologi, terjadi penurunan SpO2 menjadi 90% sehingga bayi menerima suplementasi oksigen dengan kanula nasal 0.5-1 liter/menit. Pada hari ke 7, ditemukan sekret putih kekuningan di kedua mata sehingga dilakukan pemeriksaan gram dan hasilnya negatif. Bayi kemudian diberikan levofloksasin tetes mata setiap 2 jam di kedua mata. ASI tetap diberikan menggunakan dot khusus dan pada hari ke 10 bayi diizinkan pulang dalam keadaan baik. Simpulan: Bibir sumbing biasanya disertai kelainan organ lain seperti sistem kardiovaskular. Oleh karena itu, pemeriksaan yang komprehensif harus dilakukan pada setiap kasus bibir sumbing.

Psychospiritual in palliative care services: a literature review I Putu Candra Sasmita Sutarta; Ni Ketut Putri Ariani
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Background: Palliative care provide holistic services at the physical, mental, and spiritual levels. Spiritual care is an intrinsic and essential component of palliative care that WHO has recognized. However, spiritual care is still not widely known by the community and health workers in the practice of palliative care. Methods: This literature review was written based on various books, journals, and scientific articles that related to spiritual care in palliative care. The quantitative and qualitative data were obtained, then collected and sorted into a report based on the appropriate topic. Result: Spirituality is one of the fundamental dimensions in the quality of life and maintaining culture. Thus, spirituality is an important component of palliative care. Many palliative patients understand their spiritual needs and want health professionals to help them address these needs. Various existing studies show that spiritual care provides benefits, especially in emotional needs and the search for meaning in life at the end of life. Palliative care professionals can provide spiritual care, but spiritual care is complex and requires specialized knowledge, expertise, and experience in assessing and meeting patient needs, requiring further training and education. Conclusion: Various studies have shown that palliative patients need psychospiritual care to support comfort and meaning in their lives towards the end of life. So, psychospiritual care in palliative care needs to be implemented and improved, especially in training for palliative care teams.

Hubungan nilai mean platelet volume dengan derajat klinis demam berdarah dengue di RSUD Wangaya Kota Denpasar Callista Beatrice; I Wayan Bikin Suryawan; Anak Agung Made Sucipta
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Background: DHF is a health problem in Indonesia because the morbidity and mortality rates are high, so a practical examination is needed to assess the progression of DHF to reduce its morbidity and mortality. MPV is a simple laboratory test that has not been widely studied in DHF. This study aims to determine the relationship between the MPV and the clinical degree of DHF. Method: The study was conducted with a cross-sectional design on pediatric patients aged 0 – < 18 years with DHF and treated in June 2020 – August 2021 at Wangaya General Hospital, Denpasar, Bali. DHF diagnosis was based on WHO 2011 criteria, divided into groups of DHF and DSS. The normal reference MPV is 7,5-11,5fl, and values >11,5 fl are considered high. Data were analyzed by SPSS 25. Result: Eighty patients participated in the study, 56 DHF patients and 24 DSS patients. High MPV values >11.5 fl were found more in the DSS patient group (54,16%) than the DHF group (30,35%) (OR: 3,5; 95% CI: 1,29-9,68; p = 0,023). There was a moderate negative correlation between MPV and platelet count values (r: -0,438; p < 0,05). Conclusion: MPV value has a relationship with the clinical degree of DHF. High MPV values (> 11,5 fl) have a 3,5 times risk higher for the occurrence of DSS compared to patients with normal MPV values (7,5-11,5 fl). The degree of thrombocytopenia in dengue is inversely proportional to the MPV value. Latar belakang: Demam berdarah dengue (DBD) merupakan masalah kesehatan di Indonesia karena angka kesakitan dan kematiannya yang cukup tinggi, sehingga diperlukan pemeriksaan praktis yang dapat digunakan dalam menilai progresivitas DBD agar dapat mengurangi morbiditas dan mortalitas dari penyakit ini. Mean platelet volume (MPV) adalah pemeriksaan laboratorium sederhana yang yang belum banyak diteliti perannya pada DBD. Penelitian ini bertujuan untuk mengetahui hubungan antara nilai MPV dengan derajat klinis DBD. Metode: Penelitian dilakukan dengan desain potong lintang tehadap pasien anak usia 0 – <18 tahun dengan DBD dan dirawat pada bulan Juni 2020 – Agustus 2021 di RSUD Wangaya Kota Denpasar. Diagnosis DBD berdasarkan kriteria WHO 2011, dibagi menjadi kelompok DBD tanpa syok dan sindrom syok dengue (SSD). Acuan nilai normal MPV 7,5-11,5 fl dan nilai >11,5 fl dianggap tinggi. Analisa menggunakan SPSS versi 25. Hasil: Didapatkan 80 pasien mengikuti penelitian, 56 pasien DBD tanpa syok dan 24 pasien SSD. Nilai MPV tinggi >11,5 fl didapatkan lebih banyak pada kelompok pasien SSD (54,16%) dibandingkan kelompok DBD tanpa syok (30,35%) (OR: 3,5; 95% IK: 1,29-9,68; p= 0,023). Didapatkan hubungan korelasi negatif berkekuatan sedang antara nilai MPV dan trombosit (r: -0,438; p< 0,05). Kesimpulan: Nilai MPV memiliki hubungan dengan derajat klinis DBD. Nilai MPV tinggi (>11,5 fl) memiliki risiko 3,5 kali untuk terjadinya SSD dibandingkan pasien dengan nilai MPV normal (7,5-11,5 fl). Derajat trombositopenia pada dengue berbanding terbalik dengan nilai MPV, semakin berat derajat trombositopenia semakin tinggi nilai MPV.

Platelet-rich plasma (PRP) on orthopedic clinical daily practice: a literature review Anthony Gunawan; Anak Agung Ngurah Ronny Kesuma; I Komang Agus Krisna Saputra¬¬; I Komang Mahendra Laksana
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

The use of PRP (platelet-rich plasma) is beneficial and even more important in the future. The most common indications were tendon damage (77%), osteoarthritis (68%), muscle damage (57%) and cartilage damage (51%). It is a purified autologous blood product with a higher platelet concentration than whole blood. It is rich in various cytokines and growth factors and has been shown to initiate and enhance healing by stimulating cell migration, cell proliferation, angiogenesis, and matrix synthesis. In rotator cuff injury, PRP injection led to significant long-term pain relief but not in functional improvements. In Osteoarthritis, PRP injection is associated with long-term pain relief and function improvements. PRP injection has a better outcome in VAS (visual analog scale) and DASH (The Disabilities of the Arm, Shoulder and Hand) scores in elbow ulnar collateral ligament pathologies, including lateral elbow epicondylitis. In medial epicondylitis, a paucity of studies causing therapeutic modality for PRP has not yet been established. In acute muscle injury, PRP used has no differences in imaging, pain, ROM (range of motion), muscle strength, and muscle function. In Achilles Tendinopathy, PRP injection has been associated with improvement in VAS, but no difference in VISA-A (The Victorian Institute of Sports Assesment – Achilles Questionnaire) score. However, the majority of published literature is secondary and tertiary evidence. Future studies could provide important information about the optimal concentrations of growth factors, platelets and leukocytes required for the desired effect in many specific tissues, as well as the appropriate method of administration and timing of drug application.

Karakteristik pendengaran pada pelajar pengguna peranti dengar di Denpasar, Bali, Indonesia Putri Citra Laksmi Darsana; I Made Wiranadha
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Background: Personal Listening Devices (PLDs) can increase noise-induced hearing loss in users. Currently, PLDs have been part of adolescents’ daily lifestyles. Increase of today’s audiovisual and telecommunications technologies, PLDs allow users to listen to music for extended periods and at high sound levels. It can cause chronic noise that can interfere with hearing function. This study aims to determine the characteristic of the hearing level of PLDs user students in Denpasar. Methods: A total of 48 samples were included in this study. This research is a descriptive study using a cross sectional design. This research used the cluster sampling technique by taking primary data from history taking, physical examination, and pure tone audiometry of students using PLDs at SMAN 8 Denpasar. Data analysis in this study is a descriptive statistical analysis that was analyzed using the SPSS version 24.0 for Windows. Results: The highest proportion of PLDs users is women (60,4%) and age group of 15–16 years, of which 24 students (50.0%) are 15 years old and 24 students (50.0%) are 16 years old. The most widely used type of PLDs was the earbud (81.3%). Most of the duration of using PLDs in 24 hours is < 1 hour (41.7%). As many as 34 students (70.8%) used PLDs for more than 2 years. The hearing level of students who used PLDs was obtained at most with normal hearing (0–25 dB) as many as 30 students (62.5%) in the right ear and 37 students (77.1%) in the left ear with a mean score of the hearing threshold of the right ear is 24.570±6.487dB and the left ear is 22.960±5.799 dB. Conclusion: The hearing level of students who used PLDs was obtained at most with normal hearing (0–25 dB) in the right and left ear. Latar Belakang: Penggunaan peranti dengar memiliki potensi meningkatkan resiko gangguan pendengaran akibat bising pada penggunanya. Saat ini penggunaan peranti dengar dikalangan remaja sudah menjadi bagian dari gaya hidup sehari – hari. Dengan meningkatnya teknologi audio visual dan telekomunikasi saat ini, peranti dengar memungkinkan penggunanya untuk mendengarkan musik dalam jangka waktu lama dan pada tingkat level suara yang tinggi. Hal tersebut dapat menimbulkan bising kronik yang dapat mengganggu fungsi pendengaran. Penelitian ini bertujuan untuk mengetahui karakteristik pendengaran pada pelajar pengguna peranti dengar di Denpasar. Metode: Penelitian ini melibatkan 48 sampel. Penelitian ini merupakan penelitian deskriptif dengan menggunakan rancangan potong lintang. Peneliti menggunakan teknik cluster sampling dengan mengambil data primer dari anamnesis, pemeriksaan fisik dan pemeriksaan audiometri nada murni pada pelajar pengguna peranti dengar di SMAN 8 Denpasar. Analisis pada penelitian ini adalah analisis univariat (statistik deskriptif) menggunakan program komputer SPSS versi 24.0 untuk Windows. Hasil: Didapatkan jumlah perempuan lebih banyak dibandingkan laki – laki yaitu 29 pelajar (60,4%). Rentang usia pelajar adalah 15 – 16 tahun, dimana 24 pelajar (50,0%) usia 15 tahun dan 24 pelajar (50,0%) usia 16 tahun. Jenis peranti dengar yang paling banyak digunakan adalah earbud yakni sejumlah 39 pelajar (81,3%). Sebagian besar durasi penggunaan peranti dengar dalam 24 jam adalah < 1 jam yakni sebanyak 20 pelajar (41,7%). Sejumlah 34 pelajar (70,8%) menggunakan peranti dengar selama lebih dari 2 tahun. Derajat pendengaran pelajar pengguna peranti dengar didapatkan paling banyak dengan pendengaran normal (0–25 dB) yakni sebanyak 30 pelajar (62,5%) pada telinga kanan dan 37 pelajar (77,1%) pada telinga kiri dengan nilai rerata ambang dengar pada telinga kanan adalah 24,570±6,487 dB dan telinga kiri 22,960±5,799 dB. Kesimpulan: Derajat pendengaran pelajar pengguna peranti dengar didapatkan paling banyak dengan pendengaran normal (0–25 dB) yakni pada telinga kanan dan telinga kiri.

Hubungan intensitas nyeri dengan kualitas hidup pasien kanker payudara yang menjalani kemoterapi di PPLK RSUD Dr. Soetomo Duta Angela; Djohan Ardiansyah; Desak Gede Agung Suprabawati
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Introduction: Breast cancer occurs because breast cells grow out of control. The incidence of breast cancer is still very high both in developed countries and in Indonesia. One treatment that can be done is chemotherapy. Pain is one of the effects that can occur in undergoing chemotherapy, besides the increasing stage of cancer can increase pain. This increased pain often affects a person's quality of life. This study aims to determine the relationship between pain intensity and quality of life of breast cancer patients undergoing chemotherapy at PPLK RSUD Dr. Soetomo.Methods: This research is a descriptive analytical study with a cross-sectional method. Sampling was done by total sampling that met the inclusion and exclusion criteria, then filled out the Sf-36 questionnaire and the Wong Baker pain scale. Forty respondents with breast cancer underwent chemotherapy at PPLK RSUD Dr. Soetomo. Analysis using SPSS. The Shapiro Wilk test was used to determine the normality test. Correlation using Spearman's test.Results: From 40 respondents, the youngest age in this study was 29 years old and the oldest was 61 years old. The highest level of pain in stage 4 breast cancer patients is in the mildly disturbing category, which is measured using the Wong Baker scale. The results of the Spearman test concluded that there were significant results between pain intensity and quality of life. There are 8 components in assessing the quality of life with the SF-36: physical function, physical role, emotional role, energy, mental health, social function, pain, and general health (p<0.05).Conclusion: This study shows a relationship between pain intensity and quality of life of breast cancer patients undergoing chemotherapy. Pendahuluan: Kanker payudara terjadi karena sel-sel payudara tumbuh di luar kendali. Angka kejadian kanker payudara masih sangat tinggi baik di negara maju maupun Indonesia. Salah satu pengobatan yang dapat dilakukan adalah kemoterapi. Nyeri merupakan salah satu efek yang dapat terjadi dalam menjalani kemoterapi, selain itu stadium kanker yang meningkat dapat meningkatkan rasa nyeri. Nyeri yang meningkat ini seringkali memengaruhi kualitas hidup seseorang. Penelitian ini bertujuan untuk mengetahui hubungan intensitas nyeri terhadap kualitas hidup pasien kanker payudara yang menjalani kemoterapi di PPLK RSUD Dr. Soetomo.Metode: Penelitian ini merupakan penelitian deskripsi analitik dengan metode cross-sectional. Pengambilan sampel dilakukan dengan cara total sampling yang memenuhi kriteria inklusi dan eksklusi, kemudian dilakukan pengisian kuisioner Sf-36 dan skala nyeri Wong Baker. Terdapat 40 responden penderita kanker payudara yang menjalani kemoterapi di PPLK RSUD Dr. Soetomo. Analisis menggunakan SPSS. Uji Shapiro Wilk digunakan untuk menentukan uji normalitas. Korelasi hubungan menggunakan uji Spearman.Hasil: Dari 40 responden diperoleh hasil dengan usia termuda dalam penelitian ini berumur 29 tahun dan tertua berumur 61 tahun. Tingkatan nyeri tertinggi pada pasien kanker payudara stadium 4 masuk dalam kategori agak mengganggu, yang diukur menggunakan skala Wong Baker. Hasil uji Spearman menyimpulkan adanya hasil yang signifikan antara intensitas nyeri dengan kualitas hidup. Terdapat 8 komponen dalam menilai kualitas hidup dengan SF-36, yaitu fungsi fisik, peranan fisik, peranan emosi, energi, kesehatan jiwa, fungsi sosial, rasa nyeri, dan kesehatan umum (p<0,05).Kesimpulan: Penelitian ini menunjukkan adanya hubungan antara intensitas nyeri dan kualitas hidup pasien kanker payudara yang sedang menjalani kemoterapi.

Hubungan neutrophil-lymphocyte ratio, absolute lymphocyte count, dan platelet lymphocyte ratio terhadap derajat keparahan COVID-19 Lusia Nasrani
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Introduction: The COVID-19 virus was discovered at the end of 2019 as respiratory infectious disease and has become a pandemic until now, so it is very important to predict the severity of COVID-19. Neutrophil Lymphocyte Ratio (NLR), Absolute Lymphocyte Count (ALC), and Platelet Lymphocyte Ratio (PLR) are easy, inexpensive, and fast methods as screening tools for the severity of COVID-19. The purpose of this study was to determine the relationship between NLR, ALC, and PLR to the severity of COVID-19.Methods: This study is an analytic observational study with a cross-sectional research design—retrieving research data using the total sampling method. The research data are medical records and laboratory examination data from 64 COVID-19 patients at Harapan Keluarga Hospital Cikarang in July–December 2020. The data analysis used was bivariate analysis with chi-square.Results: There were 64 samples in this study, with the majority of samples being male, the average age was 42 years, the most common symptoms were fever (81.3%) and cough (71.9%), the majority of patients had no comorbidities. There was a significant relationship between NLR, ALC and PLR with the severity of COVID-19 (p = 0.007; p = 0.002; p = 0.013). Latar belakang: Virus COVID-19 ditemukan pada akhir tahun 2019 sebagai penyakit infeksi pada pernapasan dan telah menjadi pandemi hingga saat ini, sehingga sangat penting untuk memprediksi derajat keparahan COVID-19. Neutrophyl Lymphocyte Ratio (NLR), Absolute Lymphocyte Count (ALC), dan Platelet Lymphocyte Ratio (PLR) merupakan metode yang mudah, murah, dan cepat sebagai alat skrining pada keparahan COVID-19. Tujuan penelitian ini adalah untuk mengetahui hubungan NLR, ALC, dan PLR terhadap derajat keparahan COVID-19.Metode: Penelitian ini adalah suatu penelitian observasional analitik dengan desain penelitian crosssectional. Pengambilan data penelitian menggunakan metode total sampling. Data penelitian adalah data rekam medis dan pemeriksaan laboratorium dari 64 pasien COVID-19 di RS Harapan Keluarga Cikarang pada periode Juli–Desember 2020. Analisis data yang digunakan adalah analisis bivariat dengan chi-square.Hasil: Terdapat 64 sampel pada penelitian ini dengan mayoritas sampel merupakan laki-laki, rata-rata usia 42 tahun, gejala yang paling sering ditemukan adalah demam (81,3%) dan batuk (71,9%), mayoritas pasien tidak memiliki komorbid. Terdapat hubungan yang signifikan antara NLR, ALC dan PLR dengan tingkat keparahan COVID-19 (p =0,007; p=0,002; p =0,013).Simpulan: NLR, ALC, dan PLR memiliki hubungan terhadap derajat keparahan COVID-19.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

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Editorial Address -

Location Kota denpasar, Bali INDONESIA

Abstract

Abstract

Abstract

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Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota denpasar,

Bali

INDONESIA