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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 15 Documents
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Search results for , issue "Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia" : 15 Documents clear
ANALISIS KADAR SAPONIN PADA EKSTRAK DAUN KELOR (Moringa oleifera Lam.) SECARA GRAVIMETRI Nurkhasanah, Tika Aprilia; Dhurhania, Crescentiana Emy
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1410

Abstract

Moringa leaves (Moringa oleifera Lam.) have antimicrobial activity. One of the compounds that play a role in this activity is saponins. The purpose of this study was to determine the levels of saponins present in Moringa oleifera Lam. leaf extract by gravimetric method. Moringa leaves are extracted by maceration. The existence of saponins in Moringa oleifera Lam. leaf extract was proven through qualitative tests using foam tests and color tests, while analysis of saponin levels in quantitative tests was carried out using the gravimetric method with the principle of preparation. The results of the qualitative test showed that the Moringa oleifera Lam. leaf extract was positive for saponins. Analysis of saponin content was carried out gravimetrically with the principle of precipitation. The results of saponin analysis in Moringa leaf extract obtained results with an average of 3.959% with a coefficient of variation of 0.0420%.
- PENDEKATAN KOMPUTASI UNTUK MENGATASI MALARIA DARI Coscinium fenestratum Hadi, samsul samsul; Nastiti, Kunti
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1412

Abstract

Malaria is a disease with signs of fever and is caused by Plasmodium. One way to inhibit the growth of plasmodium is using Dihydroorotate dehydrogenase inhibitors. The method used in this study was docking with laptop aspire  ES 14 equipment and PLANTS software for docking and the Discovery Studio for visualization and the materials used were compounds contained in C. fenestratum. This research was carried out using protein code 6VTY which removed water molecules and ligands that were not linked to the active site, and continued with the docking of the compounds contained in C. fenestratum. The results of this study are the Berberine docking score -82.2408; Berberrubine -84.6866 and Thalifendine -81.1591, the result of ligand interaction with Dihydroorotate dehydrogenase, the three ligands occupy the catalytic site of the enzyme, namely HIS185, PHE227, ARG 265 and CYS 175. The conclusion in this study is Berberrubine with a docking score of -82.488 is compounds that have the potential as Dihydroorotate dehydrogenase inhibitors
GAMBARAN PERENCANAAN, PERMINTAAN, DAN PENERIMAAN OBAT DI PUSKESMAS BANJARBARU UTARA TAHUN 2022 Wahyuni, Amaliyah; Fatimatuzzahra, Fatimatuzzahra; Narulita, Feni
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1475

Abstract

Drug management at the Community Health Center is an important indicator of the quality of pharmaceutical services because it determines the success of Community Health Center management. Drug management activities aim to ensure that drugs can be managed optimally. This type of research is non-experimental with a cross sectional research design using an observation sheet from retrospective data for 2022 which was carried out in February – May 2023. The population and sample are planning, demand and acceptance in the 2022 period. Secondary data processing for this research sheet Drug Needs Plan (RKO) and LPLPO for 2022. The results of the research were that the suitability of planning with the Community Health Center Formulary was 85.43% of the 103 planned drug items, there were 88 items that were appropriate and 15 items were inappropriate, the suitability of planning with demand was 4.85% of the 103 items that were planned, there were 5 items that were inappropriate. appropriate and 98 items that are not appropriate and the conformity of requests with acceptance is 3.60% of the 139 items requested there are 5 items that are appropriate and 134 items that are not appropriate.
FORMULASI DAN EVALUASI SEDIAAN FACIAL WASH EKSTRAK MIMBA (Azadirachta indica A.Juss) Caesa Anjarini, Saniyya; Kurniawari, Darini; Budi, Setia; Audina, Mia
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1519

Abstract

Neem extract is known to have antibacterial activity against acne-causing bacteria. Neem extract is made into facial wash preparations to develop herbal plants into more modern preparations. This study aims to determine the optimal formulation from the results of the physical evaluation and hedonity test and then find out that there are differences from the results of the physical evaluation of neem extract (Azadirachta indica A.Juss) facial wash preparation. The research method used was a pre-experimental laboratory one-shot case study. Physical evaluation tests included organoleptic tests, homogeneity, pH, viscosity, free alkali, foam height/foam stability, free fatty acids and hedonity (favorability test). The results of the research on the organoleptic test obtained optimal results in formula 3 and the results of the homogeneity test obtained a homogeneous preparation. Optimal pH test results in formula 3. Optimal viscosity test results in formula 3. Free alkali test results from the three formulations did not contain free alkali. Optimal foam height/foam stability test results in formula 3. Free fatty acid test results do not meet SNI facial wash standards. The results of the hedonity test showed that formulation 3 was preferred by respondents. The optimal facial wash preparation is formulation 3.
UJI AKTIVITAS ANTIDIARE TABLET EKSTRAK ETANOL DAUN KATUK (Sauropus androgynus L.) Merr. PADA MENCIT PUTIH (Mus musculus) Nurul Fadilah, Nitya; Melinia, Meena; Septiani Agustien, Gina
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1563

Abstract

Diarrhea is a condition in which a person experiences excretion of feces more than 3 times a day accompanied by an increase in volume and dilu­­tion which results in dehydration and even causes death. The aim this study was to determine the antidiarrheal activity of ethanol extract tablets of katuk leaves (Sauropus androgynus L.) Merr. which contains tannins, flavonoids and alkaloids as anti-diarrheal compounds because they can inhibit intestinal motility. This test uses the intestinal transit method which measures the length of the intestine through which the marker passes. The number of mice used was 25 which were divided into 5 groups. The positive control group 1 used loperamide HCl at a dose of 4 mg/kgBW. Group 2 was negative control with tablets without extract, Group 3 with tablet extract 80 mg/kgBW, group 4 tablets with extract dose 160 mg/kgBW and group 4 with tablet extract 320 mg/kgBW. The results of this test show that in formulation 1 it has an activity value of 40.32%, in formulation 2 it is 43.21% and in formulation 3 it is 45.2%. Tablet preparations with the best results were in formulation 3 with an extract dose of 320 mg/kgBW which showed the best results
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BENALU BATU (Begonia sp) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli Rikha Arliandini; Nur Mahdi; Ani Agustina
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1578

Abstract

Empirically, begonia leaves are used as a treatment for cancer and ulcers.  contains chemical compounds of flavonoids, alkaloids, saponins, tannins and steroids. This study aims to determine the antibacterial activity of ethanol extract of begonia and its effective concentration against Escherichia coli and Staphylococcus aureus bacteria. Extraction with 96% ethanol extract using the maceration method. Phytochemical screening test, antibacterial test using various concentrations of 30%, 50%, 100%, positive control (ciprofloxacin) and negative control (aquadest steril) using the disk diffusion method. The results of the phytochemical screening of begonia extract contain alkaloids, flavonoids and tannins. The results of the antibacterial activity test for Staphylococcus aureus were obtained with an inhibitory zone concentration of 30%, namely 3.75 mm, 50%, namely 4.37 mm, and 100%, namely 4.87 mm. Meanwhile, Escherichia coli bacteria obtained a concentration of 30%, namely 4.37mm, 50%, namely 4.62 mm, and 100% is nm 4.75mm. The diameter of the inhibition zone for the positive control of ciprofloxacin against Staphylococcus aureus bacteria was 40.31mm and Escherichia coli was 44.12mm. The ethanol extract of begonia leaves can inhibit the growth of Staphylococcus aureus bacteria at a concentration of 100% is 4.87mm and Escherichia coli bacteria at a concentration of 100% is 4.75mm
CHARACTERIZATION OF MUNDAR PERICARP (Garcinia forbesii) EXTRACT FROM BANJAR DISTRICT OF INDONESIA Rizki, Muhammad Ikhwan; Triyasmono, Liling; Alfandani, Gina; Hadiah Akbar, Nabila; Khumaira Sari, Anna
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1589

Abstract

The mundar plant (Garcinia forbesii) is a typical fruit of South Kalimantan. The people use mundar empirically as a spice, cosmetic, and medicine. The purpose of this study was to determine the characteristics of mundar extract from Karang Intan and Beruntung Baru districts in Banjar Regency. The collection of plants from two places, plant determination, and extraction with 70% ethanol. The extract was then characterized. The characterization showed that the Garcinia forbesii pericarp extract from both places was dark brown, distinctive odor, sour taste, and thick. Both extracts contained flavonoids, phenolics, tannins, saponins, glycosides, and anthraquinones. The chromatography of both extracts was the same and detected to alpha-mangosten. The extract from Karang Intan district has a yield 59.99%, total phenolic content 0.888%, moisture content 9.78%, total ash content 1.10%, and acid insoluble ash content 0.06%. The extract from Beruntung Baru district has a yield 58.74%, total phenolic content 0.823%, moisture content 9.93%, total ash content 1.59%, and acid insoluble ash content 0.04%. Garcinia forbesii pericarp extracts from from two places have the same organoleptical characteristics, phytochemical compounds, and chromatography patterns. The differences are in yield percentage, total phenolic content, water content, ash content, and acid insoluble ash content.
POTENSI ANTIDIABETIK EKSTRAK ETANOLIK BIJI SALAK (Salacca zalacca) PADA MENCIT PUTIH JANTAN GALUR SWISS (Mus musculus) YANG DIINDUKSI ALOKSAN Rukminingsih, Fef; Maya Octasari, Paulina; Kristi Nadila, Lilis; Aulia Putri, Fayza
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1600

Abstract

Traditional medicine is an alternative treatment for diabetes mellitus. Flavonoids are compounds that have the activity of lowering blood glucose levels. Snake fruit (Salacca zalacca) contains flavonoids. This study aims to determine the antidiabetic potential of snake fruit ethanolic extract (SFEE) on male white Swiss mice. This research is an experimental study that consisted of 2 stages, namely testing the antidiabetic power and testing the hypoglycemia side effects of SFEE. Each stage was tested on 5 treatment groups. The various doses used were 91 mg, 114 mg, and 137 mg of 20g mice. In stage 1, fasting blood sugar checks are carried out on days 0, 3 and 17. Meanwhile, in stage 2, fasting blood sugar checks are carried out on days 1, 7 and 14. The positive control in the stage 1 test was metformin, while the stage 2 test used glibenclamide. The results showed that varying doses of SFEE  91 mg, 114 mg, and 137 mg of 20g mice had antidiabetic power of 62.87%, 68.07%, and 70.98%. The greater the dose of SFEE, the greater its antidiabetic power. However, the larger the dose of SFEE and the longer it is administered, the hypoglycemic effects will occur
POTENTIAL OF CITRUS LEAF EXTRACT (Cymbopogon citratus (DC.) Stapf) AS AN ANTIBACTERIAL INHIBITORY of Staphylococcus epidermidis Karnelasatri, Karnelasatri; Cenwira, Wishia; Andareas, Pangeran; Santoso, Feronia Reni Cyrena
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1601

Abstract

The concerns of antibiotic resistance have increased in recently years, this issue caused by long-term repeated use of antibiotics to treat bacterial illnesses. Lemongrass leaf (Cymbopogon citratus (DC.) Stapf) is one of the natural ingredients that can be used as an alternative antibacterial. The study objective is to determine the antibacterial activity of the ethanol extract of 70% cooking leaves against Staphylococcus epidermidis using diffusion methods. In addition, the Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) of extracts were determined using liquid dilution methods. The results of this study show that extract concentrations of 1,000,000 ppm have a barrier zone in the intermediate category when compared with the positive control, that is, clindamycin. Meanwhile, the MIC value obtained is 1250 ppm, while the MBC value is 5000 ppm. The results of statistical analysis showed that there were no significant differences in the inhibition zone diameter formed between the test concentrations.
ELECTIVE COURSE DEVELOPMENT AND EVALUATION FOR THIRD-YEAR PHARMACY STUDENTS ON PHARMACY HEALTH COACHING IN INDONESIA Alexxander, Alexxander; Puspitasari, Ika; Kristina, Susi Ari; Pratiwi, Restu Dwi
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1603

Abstract

To describe our experiences in developing an elective course for third-year pharmacy students on pharmacy health coaching, as well as to evaluate its effects on students' attitudes, knowledge, and skills. The 3 Co-TEAM models consist of 18 hours of course modules. A multiple-choice and essay quiz was used to assess students' mastery of essential abilities pre and post elective courses. After the last teaching session, students' self-perceived attitude, knowledge, and skills were evaluated through a voluntary survey. Of the 60 students in the third year, only 7 students are willing to voluntarily take the elective course. The development of the curriculum resulted in a course of 3 modules, the duration of each course was 2 hours. Results showed that there was a significant improvement in knowledge overall mean score before and after the course (38.79, SD=7.11 and 81.21, SD=5.34, respectively, p<0.05). The overall mean composite score in the student’s perceived attitudes, knowledge, and skills was increased by 48.35%, 96.43%, 51.91%, respectively; p<0.05. This elective course has proven to be a successful way of educating pharmacy students. We advocate the incorporation of this style of education into the learning process to improve student's learning experiences while still supporting traditional healthcare learning.

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