cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
dwi rizki febrianti
Contact Email
dwirizkyfeby@gmail.com
Phone
+6285222400404
Journal Mail Official
jifi@stikes-isfi.ac.id
Editorial Address
Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin Jl. Flamboyan III/7C Kayu Tangi 70123 Banjarmasin Kalimantan Selatan Telepon: (0511)-3301610, 3300221 Email: jifi@stikes-isfi.ac.id
Location
Kota banjarmasin,
Kalimantan selatan
INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 23 Documents
 1   2   3 
Search results for , issue "Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia" : 23 Documents clear
UJI AKTIVITAS ANTIDIARE EKSTRAK DAUN KESUM (Polygonum minus Huds) TERHADAP MENCIT PUTIH JANTAN (Mus musculus): BAHASA INDONESIA Dian kartikasari; Puspita, Weni; Puspa Sari, Heni; Inderiyani, Inderiyani; Yolanda, Riska
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/a1k8h275

Abstract

Diarrhea is a clinical symptom of digestive disorders which is characterized by an increase in the frequency of defecation more than usual and repeatedly accompanied by a change in the shape and consistency of the feces to become soft or liquid. The aim of this research is to determine the effect of antidiarrheal activity of extract (Polygonum minus Huds) on male white mice and to find out at what concentration of extract is needed for the antidiarrheal effect on male white mice. This research was carried out by inducing mice with oleum ricini, then giving extract, then observing the time when diarrhea occurred, stool consistency, frequency of diarrhea, and the duration of diarrhea. The results obtained showed that there was a significant difference between the positive control group, 0.25% extract, 0.5% extract and 0.75% extract against the negative control group. This indicates that the three test groups have. Then from these data it can be seen that the 0.25% extract group, 0.5% extract and 0.75% extract had no significant differences from the positive control group. This indicates that kesum leaf extract with concentrations of 0.25%, 0.5% and 0.75% has activity that is close to or similar to the positive group
PENGARUH PERBEDAAN KONSENTRASI PELARUT TERHADAP KADAR FLAVONOID TOTAL DAUN SEGAR DAN DAUN KERING TANAMAN MATOA (Pometia pinnata J.R. & G.FORS) Kurnianto, Erwan; Rahman, Ika Ristia; Kartikasari, Dian; Hairunnisa
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/fkdc2t80

Abstract

Matoa (Pometia pinnata J.R. & G.FORS.) is a plant that is spread in several regions in Indonesia. This plant contains secondary metabolites that can dissolve in ethanol solvents such as flavonoids. The right type of solvent is very necessary to obtain maximum levels of active compound. This study examines the effect of ethanol solvent concentration on the total flavonoid content of fresh and dry leaves of the matoa (Pometia pinnata J.R. & G.FORS). Extraction was done using the maceration method with 70%, 80%, and 96% ethanol solvent. The determination of total flavonoid levels was carried out using the UV-Vis spectrophotometric method and AlCl3 as a reagent. The results showed that the total flavonoid content of 70%, 80%, and 96% ethanol extract of fresh matoa leaves were respectively (2.539±0.1047 mgQE/g), (1.885±0.0202 mgQE/g), (1.320±0 .0669 mgQE/g) and dried matoa leaves were (1.110±0.0448 mgQE/g), (0.870±0.0096 mgQE/g), (0.539±0.0130 mgQE/g). Based on statistical tests using the Kruskal-Wallis Test, differences in solvent concentration provide significant differences (p<0.05). 
SENYAWA BIOAKTIF DARI DAUN MIANA SEBAGAI KANDIDAT PENGHAMBAT BETA-LAKTAMASE: STUDI KOMPUTASI Oktaviana, Lina; Moulana, Mohammad Zaeni; Rusdin, Agus; Lestari, Mila Ayu; Fathin, Nayla Maymuna; Novitasari, Dhania
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/392s0e44

Abstract

Antibiotic resistance occurs through several mechanisms, one of which is  increase in beta-lactamase which can inactivate beta lactam antibiotics. The approach in finding new sources of antibiotics can be done by utilizing natural resources, one of which could be developed is miana leaves (Coleus scutellarioides). However, there has been no evaluation study related the antibacterial potential of the bioactive content  miana leaves against beta-lactam. This study analyzed the potential of bioactive compounds from miana leaves as beta-lactamase inhibitors through a computational approach. The methods used include physicochemical and pharmacokinetic profile prediction analysis, followed by pharmacophore screening and molecular docking. The results showed that most of the bioactive compounds of C. scutellarioides fulfill Lipinski's rule and show a good ADMET profile. Pharmacophore analysis produced the best model with an area under curve (AUC) score of 0.87. Molecular docking studies showed the compound 1-(4-phenylcyclohexyl)-1-hexanone had the highest binding affinity to beta-lactamase with a binding energy of -7.2 kcal/mol. This molecular interaction involves hydrogen bonding with amino acid residue GLU272 and van der Waals interaction toward ALA292 and TYR150. Therefore, bioactive compounds from miana leaves show potential as beta-lactamase inhibitors and open opportunities for the development of new antibacterial therapies based natural resources.
HUBUNGAN ANTARA KONTROL GLIKEMIK DENGAN TINGKAT KUALITAS HIDUP PESERTA PROLANIS PENDERITA DIABETES MELITUS TIPE 2 DI PUSKESMAS PRAMBANAN SLEMAN Putri, Eva Dwi Monicha; Nurinda, Eva; Wulandari, Ari Susiana; Ananda, RA Dewinta Sukma
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/vj5xas02

Abstract

The Chronic Disease Management Program (Prolanis) is the key to controlling Diabetes Mellitus (DM) in Indonesia. The Special Region of Yogyakarta is one of the provinces of Indonesia that has the second highest prevalence of DM. The majority of DM patients are in Sleman Regency.  This Prambanan Community Health Center (Puskesmas) is the second public health center with the highest prevalence of DM in Sleman. Quality of life (QOL) is the ultimate goal and important result of medical intervention for DM patients. The research methodology was a cross-sectional study conducted among 34 subjects who met inclusion and exclusion criteria. The results of this study showed that among the Prolanis participants with T2DM, 20 participants (58.8%)  had controlled glycemic and 14 participants (41.2%) had uncontrolled glycemic. QOL was found to be higher among participants with controlled glycemic (80.0%) compared to participants with uncontrolled glycemic (28.6%), and the relationship was statistically significant (p<0.05). There was a relationship between glycemic control and quality of life.  
ANALISA DRUG RELATED PROBLEMS (DRPs) PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISA DI RSUD DR HARJONO PONOROGO Septiani, Dela Dwi; R.F.X Premihadi Putra; Susilowati
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/2j8jm038

Abstract

Chronic Kidney Disease (CKD) is a progressive condition that affects more than 10% of the world's population, with more than 800 million sufferers. Treatment for CKD includes conservative therapy and renal replacement therapy, such as transplantation. Management of comorbidities in CKD patients can increase the risk of Drug Related Problems (DRPs). This study aims to determine the characteristics of CKD patients, analyze kidney conditions based on Glomerular Filtration Rate (GFR), and identify the percentage of three categories of DRPs in hemodialysis patients at Dr. Harjono Ponorogo Hospital. The study was descriptive retrospective with purposive sampling technique based on inclusion and exclusion criteria. The results showed that the majority of patients were male (59.80%), aged 56-65 years (34.31%), and had comorbid renal anemia (82.35%). The largest GFR category was G5 (<15 mL/min/1.73 m²) at 92.16%. The percentage of DRPs includes overdose (0%), drug interactions (50%), and drugs for inappropriate indications (0%).
EFEKTIVITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA ANAK DI INSTALASI RAWAT INAP DI RSUD ULIN BANJARMASIN TAHUN 2022 Nazhipah Isnani; Muliyani; Muhammad Zaini; Muhammad Muhatadin Jamil; Hadiah Akbar, Nabila
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/nxj6e492

Abstract

Pneumonia is a disease that is a problem in various developing countries, including Indonesia. Pneumonia that occurs in Indonesia tends to increase with age. This research is descriptive research with a retrospective data collection method using a sampling technique, namely total sampling. The retrospective was carried out based on previous data, referring to secondary data in the form of patient medical records while being treated at the Ulin Hospital, Banjarmasin, a sample of 98 medical records of pediatric pneumonia patients at the Ulin Banjarmasin Hospital inpatient installation for the period January-December 2022. Based on the research results obtained that patients suffering from pneumonia experienced fever for a maximum of 1-3 days totaling 87 people (89%). The highest number of antibiotics used was a single antibiotic in the cephalosporin group, namely 33 people (32%). Based on the effectiveness of antibiotics based on the duration of fever, the use of Ampicillin+gentamicin in 32 patients (31%) reduced fever more within a period of 1-3 days.
UJI AKTIVITAS ANTIBAKTERI FRAKSI ETIL ASETAT DAUN JAMBU METE (Anacardium occidentale L.) TERHADAP BAKTERI Bacillus Subtilis dan Pseudomonas aeruginosa Irawan, Ade; Ulfah, Mariam; Mansor, Khaeron
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/gaha7y05

Abstract

Infectious diseases are caused by various microorganisms including bacteria, viruses, fungi, and parasites. Cashew plants are plants that have antibacterial properties. Saponins, tannins, alkaloids, phenolics and flavonoids have antibacterial properties in cashew leaves. The purpose of this study was to determine the antibacterial activity of the ethyl acetate fraction of cashew leaves against Bacillus subtilis and Pseudomonas aeruginosa bacteria. This research is an experimental study. Ethyl acetate fraction was obtained by liquid-liquid fractionation method. Antibacterial test used concentrations of 10%, 20% and 30%, positive control Ciprofloxacin, negative control DMSO 10% with paper disc diffusion method. The results of phytochemical screening of ethyl acetate fraction of cashew leaves were positive for flavonoids, saponins and tannins. The average diameter results of the antibacterial test of Bacillus subtilis concentrations of 30% (4.5 mm), 20% (3.5 mm) and 10% (2.5 mm), while Pseudomonas aeruginosa concentrations of 30% (5 mm), 20% (3.8 mm) and 10% (1.6 mm). The ethyl acetate fraction of cashew leaves showed antibacterial activity against Bacillus subtilis and Pseudomonas aeruginosa bacteria.
ISOLASI BAKTERI ENDOFIT DARI TUMBUHAN KELAKAI (Stenochlaena palustris (Burm) Bedd). Oksal, Efriyana; Ngazizah, Febri Nur; chuchita; Irawan, Ahmad; Pereiz, Zimon
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/8x82wj94

Abstract

Kelakai (Stenochlaena palustris) is a type of medicinal fern used by the Dayak ethnic community in traditional medicine. The diverse bioactivity of kelakai is closely related to its high antioxidant content. The phytochemical compounds found in kelakai, such as phenols, flavonoids, anthocyanins, hydroxycinnamic acid, proanthocyanidins, tannins, alkaloids, saponins, carotenoids, and terpenoids, are believed to be produced by the endophytic microbes present in kelakai. Endophytic bacteria can be isolated from the plant, such as leaves, stems, bark, and roots. This research aims to isolate and identify endophytic bacteria from S. palustris. The method used is direct planting. The samples used are the leaves and stems of S. palustris. The results of the research conducted revealed six isolates of endophytic bacteria found in the leaves and stems, namely D1, D2, B1, B2, B3, and B4, which exhibit different colony morphology on the surface and color, while having similar shapes and edges. The results of the Gram staining test on the endophytic bacteria showed negative results and they are rod-shaped. In this study, endophytic bacteria S. palustris were successfully obtained from leaves and stems, which can be further analyzed for their activity.
EFEKTIVITAS EKSTRAK ETANOL DAN EKSTRAK KLOROFORM SIPUT ONCHIDID (Onchidium thyphae) SEBAGAI PENUMBUH RAMBUT PADA TIKUS (Rattus norvegicus) Wijianto, Bambang; Wijianto, Bambang Wijianto; Pratiwi, liza; Utami, Amanda Yanasari
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/fba2x720

Abstract

Hair loss is a problem that can affect appearance. A natural ingredient that can address hair loss treatment is the extract of the onchidiid snail. This study aims to test the hair growth effectiveness of ethanol and chloroform extracts of the onchidiid snail on white rats (Rattus norvegicus). The test groups of rats were divided into several groups: the Negative Group (CN), the Positive Group (CP) with candlenut oil, Treatment Group I (K1) with Chloroform Extract of the Onchidiid Snail, and Treatment Group II (K2) with Ethanol Extract of the Onchidiid Snail. Hair growth length was measured daily and processed using Image J software. The hair growth effectiveness test showed that over 14 days, the chloroform extract (K1) produced faster results compared to the other three groups, with a hair growth result of 1.61 cm on the 14th day. The findings of this study conclude that the chloroform extract of the onchidiid snail effectively promotes hair growth in male Wistar strain white rats.
AKTIVITAS ANTIOKSIDAN SERTA PENETAPAN KADAR b-KAROTEN, FLAVONOID DAN FENOL TOTAL EKSTRAK ETANOL LABU KUNING (Cucurbita moschata, (Duch.) Poir) -, Nova Anggreni; Anggreni, Nova; Mulyaningsih, Sri; Saiful Bachri, Moch.
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/ta8v4w29

Abstract

Yellow pumpkin (Cucurbita moschata) is a horticultural plant belonging to the Cucurbitaceae family. Yellow pumpkin fruit contains polysaccharides, various vitamins (including β-carotene, vitamin A, vitamin B2, tocopherol, vitamin C, and vitamin E). The abundant β-carotene in yellow pumpkin fruit has been proven to have activity in combating the negative effects of free radicals. This study aimed to determine the levels of β-carotene, total flavonoids, total phenols, and antioxidant activity in yellow pumpkin fruit (Cucurbita moschata) extracted using the maceration method with 96% ethanol solvent. The extract was qualitatively tested using thin-layer chromatography (TLC) and quantitatively tested using a UV-Vis spectrophotometer. Antioxidant activity was performed using DPPH method. The total flavonoid content in the yellow pumpkin fruit extract was 1.8 ± 0.025 mgQE/g extract, and the total phenol content was 13.9 ± 0.04 mg GAE/gram extract. Meanwhile, the β-carotene content was 16.99%, and the antioxidant activity of the yellow pumpkin fruit extract resulted in an IC50 value of 12.13 ppm, which can be classified as a very strong antioxidant.

Page 1 of 3 | Total Record : 23

 1   2   3 

Filter by Year

2024 2024


Reset
Filter By Issues
All Issue Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia Vol 6 No 1 (2023): Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019) Vol 2 No 1 (2019) Vol 1 No 2 (2018) Vol 1 No 1 (2018) More Issue