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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 19 Documents
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Search results for , issue "Vol 4 No 2 (2017): Jurnal Farmanesia" : 19 Documents clear
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli, Shigella dysentriae, DAN Salmonella typhi Sitompul, Erly; Hafizullah, Ahmad; Silalahi, Yosy Cinthya Eriwaty; Telaumbanua, Realisni
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2705

Abstract

One of the medicinal plants is the areca nut (Areca catechu L.) from the Arecae family which has the potential as an anticancer having antioxidant and antimutagenic, astringent, and anthelmintic effects. Areca nut seeds contain alkaloids, such as arekoline, arekolidine, arekain, guvakolin, guvasine and isoguvasine. This study aims to determine the characteristics of the betel nut (Areca catechu L.) simplicia, class of compounds, and the antibacterial activity of the ethanol extract of areca nut (Areca catechu L.) against the growth of Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria. The method used is the ethanol extract of areca nut (Areca catechu L.) obtained from the maceration process with 96% ethanol. The results of phytochemical screening showed that the ethanolic extract of areca nut (Areca catechu L.) contains a group of alkaloid compounds, tannins, flavonoids, saponins, and triterpenoids. The effect of giving young betel nut ethanol extract to Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria was indicated by the formation of an inhibition zone of optimum concentration. The ethanol extract of old betel nut against Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria was characterized by the formation of an optimum concentration inhibition zone. Based on the results, it can be concluded that the ethanol extract of areca nut (Areca catechu L.) has antibacterial activity against Escherichia coli, Shigella dysentriae, and Salmonella typhi.
PENETAPAN KADAR KLORIN PADA BEBERAPA MERK PEMBALUT WANITA YANG ADA DI PASARAN DENGAN METODE IODOMETRI Daulay, Anny Sartika; Lubis, Minda Sari; Sandika, M Teguh
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2706

Abstract

Sanitary napkin is a device product used by women during menstruation, sanitary napkins function to absorb blood from the vagina so that the blood that comes out does not interfere. Currently, there are many problems that arise in sanitary napkins, due to the presence of chlorine additives which function as an ingredient in the initial bleaching process of sanitary napkins. The purpose of this study was to identify the color reaction test, and to determine the chlorine content by iodometry method in sanitary napkins on the market. This research is an experimental study using a sample of sanitary napkins on the market. Sampling by random sampling (random). Determination of chlorine in sanitary napkins by testing qualitatively with a color reaction and quantitatively using the iodometric method.Based on the results of the study, it was found that of the 5 (five) samples used, 3 (three) positive samples contained chlorine, namely samples A, B and sample C. The chlorine content obtained in sample A was 0.0035%, sample B was 0.0014 % and sample C is 0.0027%. According to YLKI, the normal threshold for the use of chlorine in sanitary napkins is 5-55 ppm, so the samples tested still meet the stipulated conditions.
PENGARUH MINYAK SAWIT MERAH (RPO) DAN MINYAK ZAITUN MURNI (EVOO) TERHADAP PERTUMBUHAN RAMBUT PADA KELINCI Sofwan, Ahmad Gazali; Hafizullah, Ahmad; Adiansyah, Adiansyah; Tampubolon, Rika Rosalinda
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2710

Abstract

Haircare products are very important to prevent one of the problems of hair damage, both from synthetic and natural ingredients. One of the natural ingredients of hair care products is Red Palm Oil (RPO) and Extra Virgin Olive Oil (EVOO). This research is an experimental study that aims to see whether Red Palm Oil and Extra Virgin Olive Oil have effectiveness in growing hair. This research method used 4 groups of test animals, namely the red palm oil group, extra virgin olive oil, negative control (aqua dest), and positive control (minoxidil). The hair growth activity test was carried out by applying each formula to the marked rabbit's back and measuring the length of the hair using a caliper on the 5th, 10th, 15th, 20th, 25th, and 30th days. On the 31st day, the hair weight was tested by weighing the hair using an analytical balance. The results showed that each formula had hair growth activity, but the most effective oil preparation in accelerating hair growth was Red Palm Oil (RPO).
PENENTUAN KONSENTRASI HAMBAT MINIMUM (KHM) DARI EKSTRAK BUAH SAWO TERHADAP Salmonella typhi Nurbaya, Siti; Silalahi, Yosy Cinthya Eriwaty; Nurussakinah, Nurussakinah; Purba, Trionaldo
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2713

Abstract

Sapodilla fruit (Manilkara zapota) belongs to the Sapotaceae family. Sapodilla fruit is traditionally used in traditional medicine to cure typhoid and sapodilla fruit is not only made medicine but also the sap is taken as raw material for making chewing gum. The purpose of the examination was to determine the minimum inhibitory concentration (MIC) of sapodilla fruit extract against Salmonella typhi bacteria. The method used is the agar diffusion method using Mueller Hinton Agar (MHA) as a growth medium and paper backing. The results of the examination of the effective inhibition at a concentration of 300mg/ml with a diameter of 15.4 mm while the minimum inhibitory concentration (MIC) was at a concentration of 50mg/ml against Salmonella typhi with the smallest inhibitory diameter of 11.5 mm. From the data above, sapodilla fruit extract has a great inhibitory power against Salmonella typhi
ANALISA KADAR CEMARAN LOGAM MERKURI PADA IKAN SARDEN (Sardinella lemuru) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Silalahi, Yosy Cinthya Eriwaty; Thaib, Cut Masyithah; Nurbaya, Siti
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2714

Abstract

Food packaging in cans is a food preservation technology using high-temperature sterilization. Mercury is a heavy metal that can have a toxic effect on the body so it can cause death. This study aims to determine the levels of mercury contamination in canned sardines. The samples used in this study were 6 different brands of canned sardines. The method used to determine mercury (Hg) levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained from 6 samples of canned sardines that were positive for heavy metal mercury (Hg) were indicated by the formation of orange color with KI reagent, yellow precipitate with NaOH, white precipitate with HCl. The wavelength used is 253.7 nm. The results showed that Brand A mercury 4.9814 ± 0.0301 mg/kg, Brand B 0.8757 ± 0.0308 mg/kg, Brand C 1.4899 ± 0 mg/kg, Brand D 1.4175 ± 0 mg/kg , Brand E 0.7527 ± 0 mg/kg, and Brand F 0.5270 ± 0 mg/kg. This study concludes that the mercury content in canned fish circulating in the Medan Brastagi Supermarket is above the maximum limit allowed by the National Standardization Agency (2016) in SNI 8222-2016, which is 0.5 mg/kg.
FORMULASI DAN EVALUASI SEDIAAN LIP BALM DENGAN PEWARNA EKSTRAK UBI JALAR UNGU (Ipomoea batatas (L.) Lamk.) Supartiningsih, Supartiningsih; Sitorus, Elly Nurita; Silalahi, Yosy Cinthya Eriwaty; Khairunnisa, Khairunnisa
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2707

Abstract

Lip balm is a cosmetic preparation with the main components such as wax, fat, and oil from natural or synthesized extracts with the aim of preventing dryness of the lips by increasing lip moisture and protecting the adverse effects of the environment on the lips. The use of purple sweet potato as a dye is because purple sweet potato (Ipomoea batatas (L.) Lamk.) has an attractive color, the color of purple sweet potato is due to the presence of anthocyanin pigments which are derivatives of flavonoid compounds which are generally soluble in polar solvents. This study aims to formulate and evaluate lip balm preparations using purple sweet potato extract at concentrations of 3%, 6%, 9%, and without using purple sweet potato extract. This research is experimental research. Lip balm preparations were made by adding purple sweet potato extract with various concentrations (F1) 3%, (F2) 6%, (F3) 9%, and blank formula (F0) as the basis for lip balm preparations without purple sweet potato extract. Evaluation of the preparation includes homogeneity test, stability test, smear test, adhesion test, spreadability test, and pH test. The test results showed that purple sweet potato extract can be formulated in lip balm preparations that have a homogeneous composition, have good smearing power, good adhesion F0 (1 minute), F1 (1 minute 3 seconds), F2 (1 minute 8 seconds). seconds), F3 (1 minute 11 seconds), spreadability (5-5.7cm), pH test on all preparations showed a pH that was in accordance with the pH of the skin. And obtained formula 3 is the best formula.
PENETAPAN KADAR KALSIUM PADA BEDAK TABUR DARI BAHAN BAKU CANGKANG KERANG BULU (Anadaraantiquata) SECARA KOMPLEKSOMETRI Nurbaya, Siti; Sianipar, Artha Yuliana; Sitorus, Elly Nurita; Situmorang, Winton F.
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2708

Abstract

Until now, the utilization of clamshell waste has been limited to handicraft materials, whereas shellfish waste has a high calcium carbonate composition of about 98% which can be used as a source of calcium in the synthesis of compounds containing calcium metal. The purpose of this study was to determine the level of calcium contained in the shells of mussels and to determine the levels of calcium in the preparation of talcum powder which was added with powdered shells of feathers as an abrasive. Complexometric titration is also used to determine calcium levels in powder preparations formulated with feather shells powder. The results showed that the shells of feather shells contained calcium levels of 19.49% while the loose powder preparations contained calcium levels of 1.475%. The test results of the research on the formulation of loose powder preparations met the physical evaluation requirements. The pH test on loose powder, namely pH 7, meets the requirements of SNI 16-4399-1996, the pH value of cream cosmetic products is required to range from 4.5 to 8.0. The fine degree test is qualified because the loose powder can pass the sieving using a 100 mesh.
PENGGUNAAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereuscostaricensis (F.A.C. Weber) Britton & Rose.) DALAM FORMULASI PEWARNA RAMBUT Masyithah, Cut; Maimunah, Siti; Zuhairiah, Zuhairiah; Sitorus, Cahaya Amalia
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2711

Abstract

Hair is a symbol of beauty in humans which is one of the adnexa (parts) of the skin that grows from the skin. Hair grows from the root, hair that is in the dermis layer, and through the hair follicle channel out of the skin. There are some differences in each hair such as type, shape, amount, and color. Dragon fruit peel is an agricultural waste that contains high anthocyanin natural dyes. Anthocyanin is a dye that plays a role in giving red color which has the potential to be a natural colorant for food and can be used as an alternative to synthetic dyes that are safer for health. Anthocyanin was taken by the extraction method. The results showed that the higher the concentration of the adjuvant used, the darker the gray hair. The use of auxiliary materials in a concentration of 0.5% produces a brownish-black color, and a concentration of 1% produces a dark black color. The preparation of gray hair dye made with the formula of 2.5% dragon fruit peel extract and 1% adjuvant produces a deep black color, so pyrogallol, copper (II) sulfate, xanthan gum with a concentration of 0.5% are used in order to distinguish changes on white hair (grey), due to the EKBN formula or from added additives.
UJI AKTIVITAS EKSTRAK ETANOL BAWANG PUTIH (Alliumsativum L.)YANG DIHITAMKAN SEBAGAI ANTI INFLAMASI YANG DIINDUKSI OLEH KARAGENAN TERHADAP Mus musculus Wiratma, Dicky Yuswardi; Manurung, Kesaktian; Supartiningsih, Supartiningsih; Telaumbanua, May Fransisca
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2712

Abstract

One of the plants used as an alternative to traditional medicine is Garlic (Allium sativum L.). Garlic which is rich in organic organo sulfur compounds (amino acids and essential oils) in the form of allin has many benefits in treating various types of diseases. One of the processed forms of garlic is black garlic. Black garlic is a heating product from garlic that is heated at a temperature of 70oC with a relative humidity of 70-80%. This study aims to determine the use of black garlic as an anti-inflammatory, how to make black garlic and at what concentration black garlic has an anti-inflammatory effect. The method used in this research is a pure experimental method. The results of the %R measurement, the negative control group had the highest level of inflammation and the lowest was the black garlic extract group with a concentration of 60%. Meanwhile, in the %IR measurement, the black garlic extract group with a concentration of 60% had the greatest ability to block inflammation. From the tests that have been carried out, black garlic is obtained from heating results and the results of measuring the effectiveness of its anti-inflammatory activity, namely black garlic extract with a concentration of 60% have a better anti-inflammatory effect compared to other concentrations and diclofenac sodium.

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