cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Ratna Kumalasari
Contact Email
medicinus@dexagroup.com
Phone
+6287808191388
Journal Mail Official
medicinus@dexagroup.com
Editorial Address
Gedung Titan Center 5th Floor, Jl. Boulevard Bintaro B7/B1 No. 5, Bintaro Jaya Sektor 7, Pokdok Aren, Tangerang Selatan 15224
Location
Kota tangerang selatan,
Banten
INDONESIA
MEDICINUS
Published by PT Dexa Medica
ISSN : 1979391X     EISSN : 29638399     DOI : 10.56951
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Tujuan penerbitan jurnal Medicinus adalah untuk meningkatkan wawasan dan menambah khasanah pengetahuan para praktisi medis dan farmasis di bidang kedokteran dan kefarmasian. Ruang lingkup dari jurnal ilmiah ini adalah publikasi artikel-artikel ilmiah yang bisa disajikan dalam bentuk penelitian (research), laporan kasus (case report), teknologi dan klinis kefarmasian, serta ulasan literatur medis.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue "Vol. 35 No. 1 (2022): MEDICINUS" : 7 Documents clear
Tingkat Perbedaan Serum Nitric Oxide terhadap Derajat Keparahan dan Durasi Psoriasis Ambar Aliwardani; Bobby Febrianto; Fiska Rosita; Putti Fatiharani Dewi; Muhammad Eko Irawanto
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.306 KB) | DOI: 10.56951/medicinus.v35i1.84

Abstract

Psoriasis belongs to erythrosquamous dermatosis with uncertain etiology. Nitric oxide (NO) that acts as growth and differentiation regulator of keratinocytes is thought to play an important role in the pathogenesis of this disease. This study was aimed to determine the difference of nitric oxide serum level with the severity and duration of psoriasis patients. A cross-sectional study was conducted in 22 subjects with psoriasis vulgaris in the outpatient clinic of Dr. Moewardi Hospital Surakarta from May-September 2018 with 22 healthy individuals as control group. The severity of psoriasis was assessed using psoriasis area severity index (PASI), and serum NO is measured using Greiss method. Data then analysed using T-test and Kruskal Wallis tests (p<0.05). There was a significant difference in serum NO between the psoriasis patients and control group (p=0.020); there was no significant difference between serum NO patients and PASI score and duration of disease. It can be concluded that NO is an important factor in the inflammatory process in psoriasis, especially in active lesion.
Laporan Kasus Pyoderma Gangrenosum disertai Kandidiasis Kutis pada Wanita dengan Sindrom Metabolik Ambar Aliwardani; Fiska Rosita; Putti Fatiharani; Endra Yustin Ellistasari
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.591 KB) | DOI: 10.56951/medicinus.v35i1.85

Abstract

Introduction: Pyoderma gangrenosum (PG) is a rare inflammatory disease characterized by sterile, predominantly neutrophilic infiltration of the skin and other organs. PG is found particularly in women aged between 40-60 years. Metabolic syndrome is reported to have a potential role to induce PG. Case: A 45-year-old woman came to Dr. Moewardi Hospital with chief complaints of ulcer in the chest and legs that was preceded by reddish fluid filled bump which then broke into painful wound. History of trauma, gastrointestinal, and joint pain was denied. Dermatological examination of anterior trunk region and inferior extremity showed erythematous patches with multiple ulcers with irregular border covered with hemorrhagic crusts and necrotic tissue. Pathergy test was negative. In the right and left axillary, inframammary and inguinal, there were hyperpigmented patches with scales and satellite lesions, KOH 10% examination obtained pseudohyphae and cell budding. The patient also has metabolic syndrome. Diagnosis of PG was made based on the presence of 2 major and 2 minor criteria. Patient was given intravenous methylprednisolone 93.75 mg/24 hours, analgesics, antibiotics, topical antifungals, debridement and breast reconstructive surgery after response to steroid therapy was seen. The patient was discharges from hospital with improvement. Discussion: Metabolic syndrome is considered to be a risk factor contributing to the development of systemic chronic inflammatory processes and has been described as one of the precipitating factors for PG and skin candidiasis. Management of metabolic syndrome as the known risk factor aims to minimize the recurrence of PG in the future.
Prosedur Pembedahan pada Hiperhidrosis Aksilaris dengan Teknik Tumesen Liposuction-Curettage Danu Yuliarto; Wibisono Nugraha; Moerbono Mochtar; Ammarilis Murastami
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.739 KB) | DOI: 10.56951/medicinus.v35i1.86

Abstract

Hyperhidrosis is an excessive sweat production due to autonomic nerve dysfunction that occurs in areas with higher concentration of eccrine gland such as palms, soles of the feet, and axilla. Management of hyperhidrosis includes pharmacological and nonpharmacological approach. Patients with severe focal hyperhidrosis should consider surgical treatment or botulinum toxin injection. Tumescent liposuction with curettage is one of surgical technique option for the treatment of axillary hyperhidrosis. Case: A 32-year-old woman with complaint of excessive sweating, especially in the axillary area. The patient had received oral therapy from a dermatologist prior, but there was no improvement, so the patient was advised to undergo a surgical procedure. In this patient the tumescent liposuction-curettage procedure was performed. Discussion: Treatment of hyperhidrosis with both topical and systemic agents generally provides only temporary suppression of hyperhidrosis. In severe, disturbing cases, the treatment of choice for axillary hyperhidrosis is the surgical procedure. Combination of liposuction-curettage surgical method using tumescent anesthesia is relatively simple and safe. Reduction of apocrine gland secretion after liposuction-curettage takes a relatively long time. This surgical technique has many advantages, such as relatively minimal injury dan short recovery period. Follow-up after this combined liposuction-curettage procedure should be performed subjectively and objectively at 3, 6, and 12 months postoperative.
Pendekatan Diagnosis dan Tata Laksana Alopesia Androgenetik Ardhiah Iswanda Putri; M Yulianto Listiawan
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (203.749 KB) | DOI: 10.56951/medicinus.v35i1.88

Abstract

Androgenetic alopecia (AGA) is the most common form of alopecia, and affects both men and women. It is described as a progressive reduction in hair diameter, length, and pigmentation. The early signs of AGA can begin in adolescence, where family history is the most predisposing factor. AGA interferes with physical appearance which is an important factor in human self-image. Patients suffering from AGA can experience a significant reduction in quality of life, so they tend to seek for effective hair loss treatments to prevent further thinning and stimulate optimal regrowth. Unfortunately, drugs that have been approved for the treatment of AGA are still limited, have some potential side effects, and do not always give satisfactory results. The limited efficacy of the therapeutic regimen, poor tolerance, and lack of information about the duration of treatment as well as possible side effects can affect adherence to medications, also lead to disappointment and early discontinuation of treatment. Therefore, comprehensive AGA management and proper education are essential to obtain optimal results in the management of AGA.
Ekstrak Daun Zaitun Olea europaea L. untuk Tata Laksana Hipertensi Swandari Paramita; Fenny Yunita
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.886 KB) | DOI: 10.56951/medicinus.v35i1.89

Abstract

Hipertensi atau penyakit tekanan darah tinggi adalah kondisi medis yang dapat meningkatkan risiko penyakit kardiovaskular dan kerusakan organ target seperti penyakit jantung koroner, stroke, gagal ginjal, dan sebagainya. Kondisi hipertensi berkaitan dengan angka kematian yang tinggi di seluruh dunia. Sebagian besar pasien hipertensi memerlukan obat antihipertensi untuk mencapai target tekanan darah yang diinginkan, dengan profil keamanan yang baik dan biaya yang terjangkau. Oleh karena itu pengembangan obat herbal yang potensial untuk penanganan hipertensi dapat menjadi salah satu strategi yang dapat diupayakan untuk meningkatkan keberhasilan pengobatan hipertensi. Salah satu bahan alam yang mendapat perhatian adalah daun zaitun (Olea europaea L.). Kandungan utama dari daun zaitun antara lain adalah oleuropein yang telah diketahui memiliki efek sebagai penurun tekanan darah. Berdasarkan hasil penelitian preklinik dan uji klinik, ekstrak daun zaitun memiliki potensi untuk membantu mengendalikan tekanan darah sehingga akan menjadi pilihan terapi yang bermanfaat dalam tata laksana kasus hipertensi. Ekstrak daun zaitun juga terbukti dapat membantu memperbaiki profil lipid dengan profil keamanan yang baik.
Peran Analgesik Nonsteroidal Anti-inflammatory Drugs (NSAIDs) dan Analgesik Non-NSAIDs dalam Penanganan Nyeri Jan S. Purba
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (91.172 KB) | DOI: 10.56951/medicinus.v35i1.90

Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. The experience of pain serves as one of the most important protective mechanisms of the body. Understanding the mechanisms of pain is important for any clinician since chronic pain is a global problem that transcends all medical specialties. Chronic pain describes pain that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments. There are a variety of treatment options for people with chronic pain. The goal of pain management is to provide symptom relief and improve an individual's level of functioning in daily activities. A number of types of medications have been used in the management of chronic pain.
Analysis of Mortality Risk Factors in Children with Pneumonia in RSUD Dr Soetomo Surabaya Tutwuri Handayani; Retno Asih Setyoningrum
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (88.573 KB) | DOI: 10.56951/medicinus.v35i1.91

Abstract

Background: Pneumonia is one of the leading causes of under-five morbidity and mortality. We carried out a comprehensive study to identify risk factors contributing to both mortality and morbidity rate in children less than 5 years of age that were hospitalized with pneumonia. Objective: To evaluate mortality risk factors in children with pneumonia in RSUD Dr. Soetomo Surabaya. Methods: This is an analytic observational study using secondary data that was taken from medical record of hospitalized children with pneumonia between 2015-2018. Data was analysed using Chi-square test or Fisher’s exact test and logistic regression (p<0.05). Results: A total of 817 children with pneumonia were enrolled in this study. In children aged 2–59 months, the risk factors significantly associated with death included age, low birth weight, prematurity, breastfeeding status, pleural effusion, atelectasis, and comorbidity. Logistic regression revealed status of breastfeeding, pleural effusion, and comorbidities, influenced the mortality outcome of pneumonia. Conclusion: Nonexclusive breastfeeding, pleural effusion and comorbidities are the independent predictors of mortality in children with pneumonia. Thus, early identification and prompt management of these simple clinically recognizable predictors of death may help reduce mortality rate in such population.

Page 1 of 1 | Total Record : 7

 1 

Filter by Year

2022 2022


Reset
Filter By Issues
All Issue Vol. 38 No. 12 (2025): MEDICINUS Vol. 38 No. 11 (2025): MEDICINUS Vol. 38 No. 10 (2025): MEDICINUS Vol. 38 No. 9 (2025): MEDICINUS Vol. 38 No. 8 (2025): MEDICINUS Vol. 38 No. 7 (2025): MEDICINUS Vol. 38 No. 6 (2025): MEDICINUS Vol. 38 No. 5 (2025): MEDICINUS Vol. 38 No. 4 (2025): MEDICINUS Vol. 38 No. 3 (2025): MEDICINUS Vol. 38 No. 2 (2025): MEDICINUS Vol. 38 No. 1 (2025): MEDICINUS Vol. 37 No. 3 (2024): MEDICINUS Vol. 37 No. 2 (2024): MEDICINUS Vol. 37 No. 1 (2024): MEDICINUS Vol. 36 No. 3 (2023): MEDICINUS Vol. 36 No. 2 (2023): MEDICINUS Vol. 36 No. 1 (2023): MEDICINUS Vol. 35 No. 3 (2022): MEDICINUS Vol. 35 No. 2 (2022): MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS Vol. 34 No. 3 (2021): MEDICINUS Vol. 34 No. 2 (2021): MEDICINUS Vol 34 No 1 (2021): MEDICINUS Vol. 34 No. 1 (2021): MEDICINUS Vol. 33 No. 3 (2020): MEDICINUS Vol. 33 No. 2 (2020): MEDICINUS Vol. 33 No. 1 (2020): MEDICINUS More Issue