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Dian Andriani RD
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Fakultas Kedokteran Militer, Universitas Pertahanan Republik Indonesia In collaboration with Perdokmil (Perkumpulan Kedokteran Militer)
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The ASEAN Journal of Military and Preventive Medicine
Published by Universitas Pertahanan Republik Indonesia
ISSN : 30319447     EISSN : 3031870X     DOI : https://doi.org/10.47353/ajmpm
Core Subject :
The ASEAN Journal of Military and Preventive Medicine is an open-access, peer-reviewed scientific journal dedicated to advancing knowledge and innovation in the fields of military medicine, preventive medicine, biodefense, emergency medicine, disaster response, humanitarian health, and global public health. As one of the leading scholarly platforms in Indonesia and the ASEAN region, the journal provides an essential forum for researchers, military health professionals, clinicians, academics, and policymakers to disseminate high-quality research findings, emerging technologies, and interdisciplinary perspectives relevant to military and civilian healthcare systems. While military medicine remains the journal’s primary focus, contributions from allied disciplines with translational and practical impact are highly encouraged, particularly studies related to medical preparedness, humanitarian assistance, operational medicine, epidemiology, tropical diseases, public health resilience, and preventive healthcare strategies.
Arjuna Subject : -
Articles 6 Documents
 1 
Search results for , issue "Vol. 1 No. 2 (2024): July" : 6 Documents clear
Gene & Cell Therapy for Cancers: The Promise of Chimeric Antigen Receptor (CAR)-T Cells Taruna Ikrar
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 2 (2024): July
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i2.7

Abstract

The pharmacology of cell and genetic therapy represents a highly advanced and contemporary treatment technology, capable of addressing the root causes of numerous diseases with remarkable accuracy and precision at the DNA and molecular levels. Genetic technology aims to develop treatments for genetic disorders caused by inherited genetic mutations, which affect millions of people worldwide and are often life-threatening terminal illnesses. Moreover, pharmacologists and genetic biologists are striving to treat hereditary disorders. By integrating cell and genetic molecular biology, scientists have developed Chimeric Antigen Receptor T-Cell (CAR-T) technology, which has been approved for the treatment of blood cancer. Cell-based and genetic therapy is a groundbreaking therapeutic approach poised to become a cornerstone in the future treatment of degenerative and malignant diseases, particularly cancer, congenital or genetic disorders.
Recessive Dystrophic Bullous Epidermolysis with Squamous Cell Carcinoma: A Rare Case Report Sissy Sissy; Mahfudz Shidiq; Clara Virginia Allun; Daniel Ahmad Romero
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 2 (2024): July
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i2.8

Abstract

Epidermolysis bullosa (EB) is a genetic disorder in which the skin layer and other epithelia attached to the underlying connective tissue are disrupted with a tendency to form blisters and vesicles after mild trauma or friction. Other organs, like as the esophagus, can be damaged by some forms of EB, and subsequent problems might require several procedures. While there has been substantial progress in illness classification, specifically identifying the genes and proteins involved, there have been limited advancements in disease therapy. The care of an EB patient focuses on suppressing symptoms, protection of the skin, and minimizing complications. This case report presents the unique case of a 13-year-old girl diagnosed with recessive dystrophic epidermolysis bullosa complicated by squamous cell carcinoma. Multiple erosional efflorescences appear geographically defined boundaries covered with brownish yellow crusts, dystrophic scars, milia. Contractures of both fingers and toes (pseudosyndactyly) were present. The diagnosis was established through a comprehensive evaluation including history, physical examination, and relevant tests. The patient's parents did not have any of these problems and were not linked. There is no family history of the patient suffering from comparable problems. Therapy is therefore focused on the prevention of lesions and complications. The complexity of the therapeutic strategy depends on the severity of the patient's lesions. Optimal management of this disease can only be done through a multidisciplinary team of different disciplines. The management given is Sodium Fusidate cream every 12 hours applied to open erosions, open compresses NaCl 0.9% every 8 hours for 15-20 minutes, on crusts, levertrans on erosion areas. The prognosis for individuals with this condition remains uncertain, highlighting the challenges in addressing the complex nature of this disease.
Case Report: Effective Use of the Orticochea Flap in the Surgical Treatment of Non-Hodgkin Lymphoma Anastasia Dessy Harsono; Metaudina Chandra Pratiwi; Dominic Melino Tjokrovonco
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 2 (2024): July
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i2.9

Abstract

Non-Hodgkin lymphoma is a malignant disease arising from lymphoid tissues, primarily affecting the lymph nodes. The clinical manifestations and histological appearances of non-Hodgkin lymphoma are diverse, typically presenting with swelling, pain, and ulcers in the head and neck region. This case report discusses the management of a 55-year-old immunocompetent female patient presenting with a large, painless mass extending from the neck to the occipital region of the scalp, mimicking the features of a sarcoma. Closing scalp defects poses a significant challenge for plastic surgeons due to the limited tissue and variable elasticity of the scalp. Orticochea flap, also known as the "banana peel" flap was performed on the patient after the removal of the tumor mass. The orticochea flap technique allows for greater surface area coverage while maintaining vascularity, resulting in quicker procedures and good aesthetic outcomes.
Modified Keystone Flap: A Versatile Reconstruction for Mastectomy Defects – Our Clinical Experience Anastasia Dessy Harsono; Dominic Melino Tjokrovonco
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 2 (2024): July
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i2.10

Abstract

Introduction: The closure of extensive defects in reconstructive surgery is a common challenge. The keystone flap technique has gained popularity due to its adaptability and reliance on fascia, providing a reliable blood supply and offering a better match for skin color compared to skin grafts. However, keystone flap necrosis can occur due to tension and inadequate tissue perfusion. To address this, a modified keystone flap technique called the "doubled-handle saucepan" was developed, resulting in improved flap vitality and reduced tissue necrosis, particularly in mastectomy defects. Materials and method: We assessed 16 female patients who underwent “doubled-handle saucepan” keystone flaps after modified radical mastectomy (MRM). The average dimensions of wounds in this study were 23.1 ± 3.8 cm × 16.9 ± 2.9 cm, with the largest defect measuring 28.0 cm × 21.5 cm. The average size of the modified keystone flap was 36.3 ± 3.8 cm × 21.2 ± 2.2 cm. Results and Discussion: Modified keystone flap demonstrated effective performance in managing extensive defects without any complication. The average operation time in our study was 124.3 ± 11.2 minutes. Conclusion: The "double-handled saucepan" keystone flap technique is a unique and dependable method derived from the original keystone flap which effectively covers defects and maintains flap vitality without tension by ensuring vascularization at the skin bridge. This modified keystone flap technique proves highly effective for reconstruction after modified radical mastectomy (MRM), offering time efficiency and no need for a secondary donor site makes it an appealing alternative to free flaps or other local flap techniques in many cases.
The Role of Speckle-Tracking Strain Echocardiography in the Clinical Evaluation and Follow-up of Myocarditis with Preserved Ejection Fraction: A Case Report Ardhestiro Hanindyo Putro
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 2 (2024): July
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i2.13

Abstract

Introduction: Myocarditis has heterogeneous clinical manifestations and may be difficult to recognize when left ventricular ejection fraction is preserved. Speckle-tracking echocardiography may detect subtle myocardial dysfunction through global longitudinal strain (GLS) assessment. Case Illustration: A 30-year-old woman presented with exertional dyspnea and preceding sore throat, followed by chest pain radiating to the left shoulder. Electrocardiography showed sinus rhythm without acute ST-segment elevation, and conventional transthoracic echocardiography showed preserved LVEF (61%). Inflammatory markers and NT-proBNP were elevated. STE demonstrated markedly reduced GLS (-4.7%), especially in lateral, posterior, and anterior segments. Cardiac magnetic resonance imaging performed 10 days after symptom onset showed subepicardial late gadolinium enhancement in the basal lateral and inferolateral left ventricular walls, supporting myocarditis. Discussion: The regional distribution of impaired strain corresponded with cardiac magnetic resonance abnormalities, suggesting that STE may identify clinically relevant myocardial involvement despite normal LVEF. Serial STE showed improvement during follow-up after guideline-directed therapy and clinical stabilization. Conclusion: GLS assessment by STE is a useful non-invasive adjunct for diagnosis, risk evaluation, and follow-up of suspected myocarditis, particularly when conventional echocardiography appears normal.
The Effect of Intensive Medical Rehabilitation on the Functional Capacity of TNI Soldiers with Chronic Phase of Lower Extremity Injuries Rifqi Averrouza
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 2 (2024): July
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i2.14

Abstract

Rehabilitation plays a crucial role in the recovery of patients, improving their quality of life and reducing the risk of complications by restoring a person's functional capacity after experiencing an injury. Chronic musculoskeletal injuries that are not handled optimally have the potential to cause disability for soldiers, making it impossible for soldiers to return to duty according to their main duties. Lower extremity injury is related to the potential reduction in a person's functional capacity, related to their functions, namely mobility, fitness, strength and agility. Active military soldiers with chronic lower extremity injuries underwent an intensive-structured medical rehabilitation program 3 times a week for 8 weeks. At the end of the rehabilitation program, statistically significant differences were found in the increase in cardiorespiratory fitness capacity and agility compared to pre-intervention. Even in chronic conditions, intensive medical and structural rehabilitation programs in cases of lower limb injuries can significantly increase functional capacity in assessing cardiorespiratory fitness and agility in accordance with TNI soldier fitness standards.

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