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Muhammad Syahrir
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INDONESIA
Pharmaciana: Jurnal Kefarmasian
Published by Universitas Ahmad Dahlan
ISSN : 20884559     EISSN : 24770256     DOI : 10.12928
Core Subject : Health,
Medicine & Pharmacology
Pharmaciana is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Pharmaciana published three times a year, namely March, July and November. with ISSN 2088-4559 and e-ISSN 2477-0256. The article published in the Journal Pharmaciana selected by editors and reviewed by the reviewer. Articles published in Pharmaciana must not be published in other journals or have been previously published. Pharmaciana is indexed in google scholar, ACI (Asean Citation Index), Dimension (Crossreff), Garuda, Sinta, Sherpa Romeo, Index Copernicus International, DOAJ, and BASE. Pharmaciana is accredited by DIKTI (DGHE) of Indonesia No. 105/E/KPT/2022 April 07, 2022
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 14 Documents
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Search results for , issue " Vol 4, No 2 (2014): Pharmaciana" : 14 Documents clear
PERBANDINGAN AKTIVITAS REPELAN ANTARA KRIM MINYAK ATSIRI JAHE (Zingiber offinale, Roxb) DENGAN KRIM MINYAK ATSIRI SERE (Cymbopogon citratus (D.C) Stapf) TERHADAP NYAMUK Aedes aegypti BETINA Ikhsanudin, Azis
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.467 KB) | DOI: 10.12928/pharmaciana.v4i2.1568

Abstract

The one efforts to prevent dengue fever is to prevent mosquito bites by using mosquitorepellent preparations. The nature of the toxicity of synthetic repellent be the reason for theresearch came from the plant. Sere and ginger into one of mosquito repellent plant because it contains of natural essential oils are many. The aim of this study was to determine the comparativeability repelan effects of essential oils cream sere (Cymbopogon citratus (DC) Stapf) and ginger(Zingiber officinale Roxb). The essential oil of sere (Cymbopogon citratus (DC) Stapf and ginger(Zingiber officinale Roxb), obtained by isolation of leaves and rhizome by steam distillation ofwater which is then tested physical properties including test of adhesion, test of spreadability andtest of mosquito repellent activities. The test of mosquito repellent activities using 20 birds Aedesaegypti mosquito female per cage with the using hand of women as volunteers as much as 4people. In this study were divided into sixth formulas of test. The sixth of cream formula withvariations in the concentration of essential oils sere and ginger wherein the formula I, II and IIIcontain essential oils sere as much as 20% v/w; 30% v/ w and 40% v/w, whereas for formula IV; V;and VI contain the essential oil of ginger as much as 6.25% v/w; 12.5% v/w and 25% v/w. Data ofphysical properties test were analyzed statistically using SPSS. The results showed the cream withthe concentration of essential oils sere 40% v/w (FIII) have better outcomes than others formulascream, where than of adhesion test is 0.46 ± 0.04 seconds; of the spreadibility test is 56.32 ± 14.78cm2 and repellent effect of 3014.2 ± 20.16 seconds.
AKTIVITAS EKSTRAK RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb.) PADA RADIAL ARM MAZE DAN PASIVE AVOIDANCE TEST TIKUS MODEL DEMENSIA Prasetya, Didik Yuni; Yuliani, Sapto
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.796 KB) | DOI: 10.12928/pharmaciana.v4i2.1573

Abstract

Curcuma xanthorrhiza Roxb. is a plant containing curcumin. Curcumin has been shown toreduce oxidative damage and memory deficits associated with aging. The aim of the researchwas to know the effect of Curcuma xanthorrhiza Roxb. rhizome ethanol extract to memoryfunction on Wistar rats induced by trimethyltin. The research design was post test onlycontrolled group with 42 rats divided into 6 groups, Each group consist of 7 rats. Group I(healthy controls) were given a solution of 0.5% CMC-Na orally. Group II (negative control)were given a solution of 0.5% CMC-Na orally. Group III, IV, and V were given Curcuma xanthorrhiza Roxb. extract each 120 mg/kgBW, 240 mg/kgBW, and 480 mg/kgBW orally.Group VI (positive control) were given piracetam 500 mg/kgBW intraperitoneally. All groupswere given trimethyltin intraperitoneally except group I. Data indicating memory function wereobtained from radial maze test and passive avoidance test. Radial maze test data were analyzedby ANOVA followed by LSD test, while the passive avoidance test data were analyzed with theKruskal Wallis test followed by Mann-Whitney test. In conclusion, ethanol extract oftemulawak rhizome (Curcuma xanthorrhiza Roxb.) at doses of 120 mg/kgBW, 240 mg/kgBWand 480 mg/kgBW can prevent memory function decline on Wistar rats induced bytrimethyltin.
PEMURNIAN ETANOL HASIL FERMENTASI KULIT UMBI SINGKONG (Manihot Utilissima Pohl) DARI LIMBAH INDUSTRI KERUPUK SANJAI DI KOTA BUKITTINGGI BERDASARKAN SUHU DAN WAKTU DESTILASI Marjoni, Mhd. Riza
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.148 KB) | DOI: 10.12928/pharmaciana.v4i2.1578

Abstract

Bukittinggi city with approximately 132 industry crackers Sanjai spend 300-500 kg ofcassava per day for each industry. Solid waste production process results Sanjai crackers thisone is skin cassava. Cassava’s peel produces 15-20% carbohydrate content of 68-85% of theweight of the bulb, so it has great potential to be converted into bioethanol.Carbohydrates in the tuber peel can be processed into ethanol by fermentation and for separatingethanol from it’s mixture used method of distillation. Distillation temperature and time used affects the quality and quantity of bioethanol produced. This study aims to determine the besttime and temperature distillation to produce bioethanol at the highest levels. Ethanol contentanalysis was conducted using the specific gravity using line arregression equation and Tablegravity of Indonesian Pharmacopoeia. The results showed that the highest levels of ethanoldistillate obtained in the distillation temperature of 71o C for 5 hours is 16.60% using regressionmethods and 14.1% according to Table Pharmacopoeia with yield ranging between 2.30%-5.80% and the efficiency of distillation 28, 94% -57.50%. Time and temperature distillationhave a real impact on the levels of ethanol produced atthe level of 5%.
STUDI KELARUTAN PROPAGERMANIUM DENGAN METODE KROMATOGRAFI CAIR KINERJA TINGGI Putranti, Widyasari; Martodihardjo, Suwaldi; Lukitaningsih, Endang
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.217 KB) | DOI: 10.12928/pharmaciana.v4i2.1569

Abstract

Propagermanium, a synthetic organic compound of germanium is known as β- or biscarboxyethylgermaniumsesquioxide or Ge-132. It is found in some plants such as shelf fungus,ginseng, garlic, and Aloe vera. Ge-132 plays an important role for the pharmacological effectsof the plants. The solubility of propagermanium at a certain pH is not exactly known yet. Untilnow, the analytical methods for the analysis of Ge-132 so far have the shortcoming and thepropagermanium as germanium metal in the sample, so that improvement for propagermaniumanalysis was necessary to be conducted, primarily to be used for solubility assay. This studyaims to determine the effects of pH on the propagermanium solubility using HPLC method foranalysis. The results showed that validation parameters for analysis by using HPLC method e.iaccuracy, precision, and linearity, have met to the quantitative analysis requirements. Increasingthe pH causes increasing the solubility of propagermanium in the pH range of 3.0-3.6. Thesolubility result was 9.8514; 10.4204; 12.5446 mg/mL on pH 3.0; 3.3; 3.6.

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