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Pharmaciana: Jurnal Kefarmasian
Published by Universitas Ahmad Dahlan
ISSN : 20884559     EISSN : 24770256     DOI : 10.12928
Core Subject : Health,
Medicine & Pharmacology
Pharmaciana is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Pharmaciana published three times a year, namely March, July and November. with ISSN 2088-4559 and e-ISSN 2477-0256. The article published in the Journal Pharmaciana selected by editors and reviewed by the reviewer. Articles published in Pharmaciana must not be published in other journals or have been previously published. Pharmaciana is indexed in google scholar, ACI (Asean Citation Index), Dimension (Crossreff), Garuda, Sinta, Sherpa Romeo, Index Copernicus International, DOAJ, and BASE. Pharmaciana is accredited by DIKTI (DGHE) of Indonesia No. 105/E/KPT/2022 April 07, 2022
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 13 Documents
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Search results for , issue " Vol 6, No 2 (2016): Pharmaciana" : 13 Documents clear
Penggunaan antibiotik di dua apotek di Surabaya: identifikasi faktor-faktor yang mempengaruhi kepatuhan pasien tamayanti, wahyu dewi; D.M. Sari, Windrianita; Dewi, Bernadette Dian Novita
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.813 KB) | DOI: 10.12928/pharmaciana.v6i2.4038

Abstract

Attention to factors that affects proper use of antibiotics need to be conducted to prevent community resistance. This study was aimed to identify factors that affect patients’ compliance of antibiotic use in two pharmacies in Surabaya, Bhumyamca (A) and Tiara 2 (B). Subject of this study was people who purchased antibiotics in the two pharmacies. Data were collected through questionnaires, analyzed using descriptive statistic, and underwent Hosmer and Lemeshow’s multiple regression tests. Factors such as: age, gender, income, duration and pattern of antibiotics use, antibiotics information, complaint and action after antibiotics side effect were observed. There were 94 respondents mainly 26 - 31 of age met the inclusion criteria. Female respondents in A were 74% and 68% in B. Respondents income was 2 to 3 million rupiah, in A (83%) and B (54%). Respondents use antibiotics mainly for 3 to 5 days, in A (47%) and B (50%). Most respondents use antibiotics after meals in A (92%) and B (88%). Antibiotics information was obtained mainly from healthcare providers in A (92%) and B (85%). Respondents had no complaints after antibiotics use in A (87%) and B (73%). Respondents (44%) stop antibiotics when complaints were occurred both in A and B, whereas 56% visited clinician. Respondents in A (86%) and B (89%) were consumed antibiotics in accordance to usage instruction. Conclusively, no factor was associated to patients’ compliance, except pattern of administration in B (0.011).
Efek hidrogel getah jarak cina (Jatropha multifida Linn.) berbasis karagenan kappa dan karagenan iota terhadap penyembuhan luka tikus wistar jantan Lestari, Fetri; Darma, Gita Cahya Eka; Kartika, Rikka
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.778 KB) | DOI: 10.12928/pharmaciana.v6i2.3899

Abstract

Jatropha multifida Linn. latex has been reported in many study for its activities to treats wound. Preparation of hydrogels containing 3% of Jatropha multifida Linn. latex with variety of base polymers kappa carrageenan and iota carrageenan  was conducted and met good characteristics. This study aimed to evaluate effect of both hydrogels to promote wound healing in Wistar rats. Tests carried out on five groups of rats with 1.5 cm diameter of wound in the back area, consisting of a control group, two test groups were each treated by 2% kappa carrageenan-based hydrogel (kappa-hydrogel group) and 2% iota carrageenan-based hydrogel (iota-hydrogel group) of the latex, and two groups were each given a different hydrogel base according to type of hydrogel tested. Effect on wound healing was assessed by parameters including wound drying period, scab forming period, and the change in diameter of the wound. Results show kappa-hydrogel group achieve the most rapid wound healing compare to the control group significantly (p<0,05) and the iota-hydrogel group on wound drying period (16.6 ± 2.2 hours) and scab forming period (92.6 ± 2.2 hours). Kappa-hydrogel group also show best changes in diameter of the wound at day 21 which is reduced to 0.02 ± 0.03 cm, compare to the control group and iota-hydrogel group. As a conclusion, the 2% kappa carrageenan-based hydrogel containing 3% of Jatropha multifida Linn. latex produce better effect to promote wound healing than iota carrageenan-based hydrogel in this study. 
Uji sitotoksisitas dan antiproliferatif ekstrak etanol daun leunca (Solanum Nigrum,L) terhadap sel raji Dona, Rahma; Sulistyani, Nanik; Nurani, Laela Hayu
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (449.264 KB) | DOI: 10.12928/pharmaciana.v6i2.3506

Abstract

Leunca (Solanum nigrum,L.) is one of the medicinal plant which used society for traditional medication as antipyretic, hypotensive and anticancer. The aim of  this research was to know an anticancer activity of ethanol extract of leunca leaves, emphasized on an ability to inhibit the growth Raji cell. Ethanol extract took from leunca leaf powder that epitomized using ethanol solvent by Soxhlet instrument. Citotoxicity test was done by incubating Raji cell at a density of 2x104 with treatment using ethanol extract from leunca (Solanum nigrum L.) leaf in several concentration 500; 250; 125; 62,5; 31,25; 15,62; 7,81 and 3,90 µg/ml. A test was done by MTT method and the percent of cell mortality was calculated. The LC50 values were calculated using probit analysis. The research continued with antiproliferation test on treatment sample concentration 50; 25 µg/ml with cell control for 24, 48, and 72 hours.The result of research indicate that ethanol extract of leunca leaves had cytotoxic effect towards Raji cell with LC50 values 59,22 µg/ml. The result of  antiproliferation test showed that there were the growth of inhibitation on treatment sample with doubling time values 69,56 hour at concentration 50 µg/ml; 60,00 hour at concentration 25 µg/ml, and doubling time cell control is 44,98 hour.

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