cover
Contact Name
Made Krisna Adi Jaya
Contact Email
krisnaadijaya598@gmail.com
Phone
+6281293208990
Journal Mail Official
jpsa@unud.ac.id
Editorial Address
Gedung AF Jalan Kampus Udayana, Bukit Jimbaran Badung - Bali Indonesia 80239 Phone: +62 361 4747 770
Location
Kota denpasar,
Bali
INDONESIA
Journal Pharmaceutical Science and Application (JPSA)
Published by Universitas Udayana
ISSN : 23017694     EISSN : 23017708     DOI : https://doi.org/10.24843/JPSA.2020.v02.i01
Core Subject : Health, Science,
Journal of Pharmaceutical Sciences and Applications (JPSA) is an online and print out Journal. This Journal publishes original research work that contributes significantly to further the scientific knowledge in pharmaceutical sciences and applications. Pharmaceutical Technology Pharmacognosy Natural Product Research Pharmaceutics Novel Drug Delivery Biopharmaceutics Pharmacokinetics Pharmaceutical/Medicinal Chemistry Computational Chemistry and Molecular Drug Design Pharmacology and Toxicology Pharmaceutical Analysis Pharmacy Practice Clinical and Hospital Pharmacy Community Pharmacy Cell Biology Genomics and Proteomics Pharmacogenomics Bioinformatics and Biotechnology The Journal publishes original research work either as a Full Research Paper or as a Short Communication. Review Articles on a current topic in the said fields are also considered for publication by the Journal. Journal of Pharmaceutical Scince and Application (JPSA), a half yearly publication, serves the need of different scientists and others involved in Pharmaceutical science research and application. All contribution to JPSA are reviewed by peer review process and copy editing process with the understanding that they have not been published previously and are not under consideration for publication elsewhere.
Articles 6 Documents
Search results for , issue "Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application" : 6 Documents clear
A REVIEW OF PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES OF Piper retrofractum Vahl. Ni Putu Eka Leliqia; Ni Komang Sri Lumbung Artha Wardani
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p05

Abstract

Background: Javanese long pepper (Piper retrofractum Vahl.) is a plant that commonly found in Southeast Asia and is empirically used to treat various diseases. It is known that the phytochemical content in plants is one factor responsible for its pharmacology activities. The study of the pharmacological effects of herbal ingredients both pre-clinically and clinically is an attempt to prove their empirical properties. Aims: This review article aims to provide information to academics and the public regarding phytochemical studies and pharmacological activity that have been carried out regarding the Javanese long pepper plant. Methods: Article preparation was carried out through literature studies from various national scientific journals, international journals, and online reference books. Javanese long pepper data search system was based on chemical content and pharmacological activity studies either in vitro, in vivo, or clinical trials. Results: Phytochemical studies have shown that the plant parts of Javanese long pepper contain compounds such as alkaloids, saponins, tannins, flavonoids, steroids, triterpenoid, and glycosides. Based on studies of its pharmacological activity, Javanese long pepper has been reported to have antimicrobial, antioxidant, cytotoxic, analgesic, androgenic, aphrodisiac, antihyperlipidemic, antihyperuricemic, lowering leukocyte count, antileishmanial and immunostimulant effects. Conclusion: The efficacy of Javanese long pepper has been scientifically proven to have pharmacological effects either through in vitro or clinical studies which can be taken into consideration for the development of traditional medicinal products. Keywords: Javanese Long Pepper, Piper retrofractum, Phytochemical, Pharmacology activity
REVIEW OF SOME EUPHORBIACEAE PLANTS IN USADA TARU PRAMANA AND ITS PHARMACOLOGICAL ACTIVITIES I Gede Bangkit Adi Sentosa; I Kadek Suardiana; A.A Gede Rai Yadnya-Putra
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p01

Abstract

Background: World Health Organization (WHO) states that up to 65% of the world's population uses traditional medicines. Indonesia is one of the countries where most people still use traditional medicine, especially in Bali. The traditional Balinese plant-based medical system that has existed for a long time and is still inherited today is Usada Taru Pramana. One of the many plants found in Usada Taru Pramana is the Euphorbiaceae. Objective: This work aims to review some of the Euphorbiaceae plants written in Usada Taru Pramana, which have a variety of potential pharmacological activities. Method: This article review using a primary and secondary data sources. Results: Some parts of the Euphorbiaceae plants in Usada Taru Pramana contain important phytochemical constituents such as phenols, alkaloids, flavonoids, saponins, tannins and essential oils. Some of the potential pharmacological activities that have been tested are anti-inflammatory, analgesic, and antibacterial. Conclusion: The Euphorbiaceae plants in Usada Taru Pramana have a variety of phytochemical constituents and correlates with its pharmacological activities. Further research needs to be conducted to explore other Euphorbiaceae plants species in Usada Taru Pramana to find compounds and other pharmacological activities to deal with various diseases in the community. Keywords: Usada Taru Pramana, Euphorbiaceae, Phytochemical Constituents, Pharmacological Activities
PHARMACIST’S ROLE IN MEDICATION RECONCILIATION TO PREVENT THE RISK OF MEDICATION ERROR AT BALI MANDARA HOSPITAL Ida Ayu Manik Partha Sutema; IBN Maharjana
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p06

Abstract

Background: Pharmacists have an important role in implementing drug reconciliation. The implementation of drug reconciliation allows the process of identifying drug administration errors due to information gaps, which we can avoid by optimizing information as early as possible at every shift in the process of providing health services through the reconciliation process. This process is crucial, especially for groups of patients with chronic diseases who have a high risk of changing health care delivery settings. Failure to identify results in errors in administering drugs that lead to worsening clinical conditions, resulting in increased service needs and health costs. Objective: Provides information about the tendency of pharmacists who work at the UPTD Bali Mandara General Hospital to reduce drug use errors through the drug reconciliation program. Methods: Thematic analysis of structured interview results. Results: Almost all participants (6 out of 8 pharmacists) tend to be willing to be involved in the drug reconciliation process. There are three main themes of consideration that underlie the tendency of pharmacists to be willing to be involved in the drug reconciliation process, namely, related to understanding the definition, purpose, and consistency of the implementation of reconciliation. In controlling the incidence of medication errors, the biggest preventable errors through medication reconciliation are drug duplication and drug discrepancy. Conclusion: The tendency for pharmacists to be involved is good, and the tendency to control the risk of medication errors is still lacking in terms of communication and consistency in filling out by all officers. Keywords: Pharmacist’s role, drug reconciliation, risk of medication errors
A REVIEW OF PHYTOCHEMICAL PROPERTIES, ANTIBACTERIAL ACTIVITY, AND TOXICITY STUDY OF Averrhoa bilimbi LEAVES AND FRUIT Ni Putu Eka Leliqia; Intan Safitri
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p04

Abstract

Background: Averrhoa bilimbi or starfruit is a plant that is commonly found in Indonesia. A. bilimbi is widely used as herbal therapy against various diseases, especially those caused by bacteria. Objective: This article is intended to provide information regarding the chemical content of A. bilimbi, its antibacterial potential, and its safety level. Methods: The preparation of this article used a systematic literature review method of articles that have been published in both national and international scientific journal. Result: Leave and fruit of A. bilimbi is known to contain several classes of primary and secondary metabolites, namely carbohydrates, proteins, fats, flavonoids, alkaloids, glycosides, saponins, tannins, triterpenoids, and steroids. A. bilimbi also contains several macros and micro minerals including calcium (Ca), magnesium (Mg), and zinc (Zn). A. bilimbi could inhibit the growth of various Gram-positive and negative bacteria which have been proven through in vitro testing with diffusion and dilution methods. Based on the acute toxicity study, it was found that 80% ethanol extract of A. bilimbi fruit had an LD50 value of above 5.000 mg/kg BW so that it is practically non-toxic. Based on sub-chronic toxicity of A. bilimbi up to a dose of 500 mg/kg BW there was no death in the test animals and shows a toxic effect. Conclusion: The leaves and fruit of A. bilimbi have antibacterial activities. The compounds contained in A. bilimbi are thought to have a role in its antibacterial activity. Based on several toxicity studies, the ethanol extract of A. bilimbi has been proven safe to use. Keywords: Averrhoa bilimbi, Starfruit, Antibacterial, Chemical Properties, Toxicity.
THE IMPLEMENTATION STUDY OF STORING AND REPORTING OF NARCOTICS AND PSYCHOTROPICS AT PHARMACIES IN DENPASAR CITY, BALI PROVINCE Arie Dharma Putra Nugraha; Kadek Hendra; I Made Agus Gelgel Wirasuta
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p02

Abstract

Introduction: Storage and reports of narcotics and psychotropics in pharmacy must be carried out according to standard operating procedures which are based on legislation on maintaining safety, efficacy, and quality of the drugs. Objective: This study aimed to observe the implementation process of narcotics and psychotropic storing and reporting in accordance to the law in force in several pharmacies in Denpasar City. Methods: Five biggest pharmacies located in Denpasar City were picked by a purposive sampling method. This study used a descriptive observational method to provide a brief overview of the term and condition of narcotics and psychotropic storing and reporting that implemented in real-time in the pharmacies. Results: Overall, the study revealed that the majority of pharmacies were successfully in term of fulfilling the various aspects of narcotics and psychotropic storing and reporting, including the storage of drugs at the special cabinets, in special the implementation process of narcotics and psychotropic that cited in the Regulation of The Minister of Health of the Republic of Indonesia Number 73 of conditions according to safety and stability, FEFO and FIFO systems, manual and electronic stock cards system, separation of damaged and/or expired drug, inventory stock, and compliance and completeness of reporting using SIPNAP. Conclusion: Responsible pharmacist must always evaluate the storage and reporting of narcotics and psychotropic in the pharmacy to guarantee quality and maintain suitability of the pharmaceutical services process according to established standards. Keywords: forensic pharmacy, storing and reporting, narcotics and psychotropic, legislation
MONITORING DRUG THERAPY IN X’s PHARMACY IN BADUNG REGENCY Pratiwi Diva Yanti Luh; I M.A.G. Wirasuta; Luh Rai Maduretno Asvinigita
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p03

Abstract

Background: Monitoring drug therapy based on Permenkes RI No. 73 of 2016 is one of the pharmaceutical care standards in pharmacy practice. Monitoring drug therapy is a process that includes activities to ensure safe, effective and rational drug therapy for patients. Patients who receive drug therapy are at risk of experiencing drug-related problems. Objective: This study aims to determine the implementation of monitoring drug therapy in one pharmacy in Badung Regency. Methods: The type of research is a descriptive observational study conducted by interview session one pharmacist in X Pharmacy, then analyzed descriptively according to Permenkes RI No 73 of 2016. Results: The results showed that in January-June 2020 there were 34 patients with disease categories requiring monitoring drug therapy: 27 patients with asthma (79%), six patients with diabetes (18%), and one patient with tuberculosis (3%). Patients with the largest visits were geriatric, which were 19 out of 34 patients. Conclusion: The monitoring of drug therapy at Pharmacy X has fulfilled all the parameters in the Standard Operating Procedure (SOP) for the implementation of in Pharmacy based on Permenkes RI No.73 of 2016.Keywords: Monitoring drug therapy, Implementation, Pharmacy, Pharmacist

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