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INDONESIA
E-Jurnal Medika Udayana
Published by Universitas Udayana
ISSN : 23031395     EISSN : 25978012     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah ilmiah E-Jurnal Medika Udayana menerima naskah dari mahasiswa PSPD FK UNUD, baik berupa karangan asli atau laporan penelitian, ikhtisar pustaka, laporan kasus, maupun surat-surat untuk redaksi. Naskah yang dikirimkan untuk majalah ilmiah E-Jurnal Medika Udayana adalah naskah belum pernah atau tidak akan dikirim ke majalah lain. Bahasa yang digunakan adalah bahasa Indonesia
Arjuna Subject : -
Articles 12 Documents
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Search results for , issue "vol 2 no4 (2013):e-jurnal medika udayana" : 12 Documents clear
IDENTIFICATION OF VARIOUS PROBLEMS ON BREAST CANCER PATIENT IN YOUNG WOMEN Devy Ade Kusyanti
E-Jurnal Medika Udayana vol 2 no4 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.5 KB)

Abstract

Breast cancer is a cancer that forms in tissue of the breast such as lactiferous duct, lobules and nipple. Around hundreds of breast cancer cases in the world, less than 0,1% occur in young women less 20 years old, 1,9% on 20 and 34 years old, and 10,6% between 35 and 44 years old. Various problems of breast cancer patients in young women that genetics issues, diagnostic issues, management issues, fertility issues, and quality of life and psychosocial issues are a particular challenge that need a special attention and solution in future. A multidisciplinary team is needed as a solution on the future.
MELATONIN DAN MELATONIN RECEPTOR AGONIST SEBAGAI PENANGANAN INSOMNIA PRIMER KRONIS Ni Luh Putu Ayu Maha Iswari; Anak Ayu Sri Wahyuni
E-Jurnal Medika Udayana vol 2 no4 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.633 KB)

Abstract

Melatonin is a hormone that has an important role in the mechanism of sleep. Hypnotic effects of melatonin and melatonin receptor agonist are mediated via MT1 and MT2 receptors, especially in circadian rhythm pacemaker, suprachiasmatic nucleus, which is worked on the hypothalamic sleep switch. This mechanism is quite different with the GABAergic drugs such as benzodiazepine. Agonist melatonin triggers the initiation of sleep and normalize circadian rhythms so that makes it easier to maintain sleep. The main disadvantage of melatonin in helping sleep maintenance on primary insomnia is that the half life is very short. The solution to this problem is the use of prolonged-release melatonin and melatonin receptor agonist agents such as ramelteon. Melatoninergic agonist does not cause withdrawal effects, dependence, as well as cognitive and psychomotor disorders as often happens on the use of benzodiazepine.  

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