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All Journal Jurnal Kesehatan Saelmakers PERDANA (JKSP) Masker Medika Jurnal Kesehatan Abdurrahman Lentera Perawat
Sumantri, Apria Wilinda
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Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : Jurnal Kesehatan Saelmakers PERDANA (JKSP)

 1 
EFEKTIFITAS ANTIKANKER FRAKSI (Curcuma zedoaria) DAN PENGARUHNYA TERHADAP EKSPRESI GEN CASPASE 3 PADA SEL HELA SECARA IN VITRO Sumantri, Apria Wilinda
Jurnal Kesehatan Saelmakers PERDANA (JKSP) Vol 1 No 2 (2018): Jurnal Kesehatan saelmakers perdana
Publisher : Fakultas Ilmu Kesehatan Universitas Katolik Musi Charitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (268.054 KB) | DOI: 10.32524/jksp.v1i2.374

Abstract

Aim : The purpose of this research was the evaluate the efficacy of anti-cancer of active fraction of temu putih (Curcuma zedoaria) and their effects on expressetion caspase 3 in Hela cells in vitro Method: Do experimental study in Vitro the research population was whie the Hell cell meanwhile the research sample was HeLa cell that grow normally in cell number of 1 x 104 cell/well. The treatment group was ethanolextract, n-hexane fraction, ethyl acetatefraction and ethanol-water fraction of temu putih (Curcuma zedoaria ) were divided into 6 concentrations, that is 1000, 500, 250, 125, 62,5 dan 31,25 ug/ml; I negative control group ; and the positive control group of cispilatin with a concentration of 200, 100, 50, 25, 12,5 dan 6,25 ug/ml. the data were analyze SPSS Version 20. Result: The research findings showed that the n-hexane fraction of temu putih (Curcuma zedoaria) with the concentration of 154,261 ug/ml has the ability to induce apoptosis of 42.34% and increased the expression of caspase 3of 29,44% in Hell cells. Where as the IC50  Valuve of 20,823 ug/ml. Conclusion :       I can be said that the n-hexane fraction has the equivalent ability tp cisplatin 200 mg/ml in inhibiting growth and its effect on the expression of caspase 3 in HeLa cells In Vitro Keywords : N-hexane fraction, Temu putih (Curcuma zedoaria), anti-cancer, HeLa cells, Caspase 3
HUBUNGAN KENAIKAN BERAT BADAN DENGAN LAMA PEMAKAIAN KONTRASEPSI SUNTIK 3 BULAN Sumantri, Apria Wilinda
Jurnal Kesehatan Saelmakers PERDANA (JKSP) Vol 2 No 2 (2019): Jurnal Kesehatan Saelmakers PERDANA
Publisher : Fakultas Ilmu Kesehatan Universitas Katolik Musi Charitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.026 KB) | DOI: 10.32524/jksp.v2i2.566

Abstract

Family planning is the most basic and primary preventive health care effort, as well as the prevention of death. Family planning services can be done with the use of contraceptives. Contraceptive 3-month injection is a type of fluid injected into the female body intramuscularly (3 months) . To know weigh relationhip increasemen wingh the use of 3 month injectable village laya working area UPTD community health center tanjung agung baturaja barat 2018 year. of Analytic survey research with cross sectional approach. sample research taken by accidental sampling with a large sampe of 30 respondents Data can be by using the observation instrument, after all data collected then performed data processing using SPSS program version 22, .. Univariate analysis result, from 80 respondents found 57 (71,2%) using injectable contraception, 43 (75,4%) who gained weight, 14 (24,6%) who did not gain weight. From result of statistic analysis obtained pvalue: 0,02. The existence of 3 Months KB Injections Connection with Weight Gain Increase in Laya Work area UPTD Puskesmas Tanjung Agung Year 2018. Relationship increasment wing the use of 3 month injectable. Increasement weingh, cross sectional, statistical test Chi-Squeare.
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