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All Journal Jurnal Media Gizi Indonesia (MGI) JATI EMAS (Jurnal Aplikasi Teknik dan Pengabdian Masyarakat) Journal of Experimental and Clinical Pharmacy (JECP) Indonesian Journal of Pharmaceutical Education Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Health & Medical Sciences Journal of Innovative and Creativity Journal of Community and Clinical Pharmacy Jurnal Riset dan Pengabdian Interdisipliner
Madania, Madania
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Analisis Penerapan Metode ATC/DDD dan DU90% Dalam Penggunaan Antibiotik Pada Pasien Rawat Inap Rumah Sakit Stella Maris Makassar Arsyad, Rival Al-fazri; Pakaya, Mahdalena Sy.; Paneo, Mohamad Aprianto; Rasdianah, Nur; Madania, Madania
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Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jrpi.v3i1.36531

Abstract

The antimicrobial resistance (AMR) crisis poses a serious threat to global health, making the rational use of antibiotics a priority within Antimicrobial Stewardship (AMS) programs. This study aims to evaluate the patterns and quantity of antibiotic use among inpatient populations at Stella Maris Hospital Makassar using the Anatomical Therapeutic Chemical (ATC) classification, Defined Daily Dose (DDD), and Drug Utilization (DU) 90% methods. This research employed a retrospective descriptive observational design using medical record data of patients who received antibiotic therapy from October to December 2024. The analysis was conducted by calculating DDD per 100 patient-days and identifying antibiotics contributing to 90% of total use. The results showed eight types of antibiotics were utilized. The three antibiotics with the highest DDD/100 patient-days were Cefuroxime (13.43), Ceftriaxone (11.8), and Cefotiam (10), which, together with Moxifloxacin, were included in the DU 90% segment. The predominance of second-generation cephalosporins—particularly among diagnoses such as unspecified fever, bronchiectasis, typhoid, and bronchitis—indicates a tendency toward broad-spectrum empirical therapy in chronic pulmonary conditions such as COPD and bronchiectasis. In conclusion, antibiotic use at Stella Maris Hospital Makassar is dominated by the cephalosporin class, highlighting the need for ongoing evaluation and strengthened implementation of AMS programs to optimize antibiotic therapy, improve treatment effectiveness, and reduce the risk of increasing antimicrobial resistance at the hospital level.
Co-Authors Akuba, Juliyanti Amran, Rosmala Anggai, Rifka Anggraini Arsyad, Rival Al-fazri bangol, asnia asnia Djuwarno, Endah Nurrohwintah Dr. Apt. Hamsidar Hasan S.Si.,M.Si Endah Nurrohwinta Djuwarno Fika Nuzul Ramadhani Giasi, Mohamad Hamzah, Alifiah Ramawaty Hiola, Faramita Igirisa, Fitriwiah Julianti, Natasya Melly Kadullah, Siti Fauziah La Ode Aman Lasimpala, Natasya Indaputri LATIF, MULTIANI S Latif, Multiani S. lawani, putri Mahdalena Sy Pakaya Makkulawu, Andi Manno, Mohamad Reski Mohamad Aprianto Paneo Muhammad Taupik Mursyidah, Andi Nangsih Sulastri Slamet Nur Ain Thomas Nur Rasdianah Papeo, Pirdawati Paputunngan, Mitha Podungge, Yusni Puhi, Melly Agustin Is Puluhulawa, Lisa Efriani Putri, Alecia Febriani Rasdiana, Nur Robert Tungadi S. Latif, Multiani Sapiun, Zulfiayu Sumaga, Khairunnisa Alya Suryadi, A. Mut’thi Andi Suryadi, Mu'thi Andy Teti Sutriyati Tuloli Toluli , Teti Sutriyati Tuloli, Tety Widy Susanti Abdulkadir Yanti , Febri Dwi