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All Journal Journal of General Procedural Dermatology and Venereology Indonesia
Ariyati Yosi
Department of Dermatology and Venereology Faculty of Medicine Universitas Sumatera Utara, H. Adam Malik General Hospital
Medicine & Pharmacology

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The use of systemic medications in pediatric dermatoses: A review Shanthi Narla; Githa Rahmayunita; Rinadewi Astriningrum; Tor Shwayder; Ariyati Yosi; Henry W. Lim
Journal of General - Procedural Dermatology and Venereology Indonesia Vol 4, No 1 (2019): December 2019
Publisher : Universitas Indonesia

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Abstract

Research has begun to illustrate a favorable efficacy and side-effect profile for many systemic agents used in pediatric dermatological conditions (i.e. atopic dermatitis, psoriasis, scleroderma, alopecia areata, chronic spontaneous urticaria, autoimmune blistering disorders, and hidradenitis suppurativa) despite not having extensive randomized clinical trials. The purpose of this article is to summarize the available data on the treatment regiments, safety, and efficacy of systemic immunosuppressants, including the newer biologics, focusing on the most up-to-date systematic reviews or randomized clinical trials. The review demonstrates that many of the present studies lack data on long-term efficacy and consist of small patient populations. Further research into the long-term safety of these systemic medications is of vital importance especially due to the chronic nature of most pediatric dermatological conditions that require the use of systemic agents. Keywords: systemics, immunosuppressant medications, biologics, pediatric dermatology conditions
Correction Shanthi Narla; Githa Rahmayunita; Rinadewi Astriningrum; Tor Shwayder; Ariyati Yosi; Henry W. Lim
Journal of General - Procedural Dermatology and Venereology Indonesia Vol 4, No 1 (2019): December 2019
Publisher : Universitas Indonesia

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Abstract

Narla S, Rahmayunita G, Astriningrum R, Shwayder T, Yosi A, Lim HW. The use of systemic medications in pediatric dermatoses: A review. J Gen Proced Dermatol Venereol Indones. 2019;4(1):25-38 In the article above, Table 1 is reprinted from Journal of the American Academy of Dermatology, Vol 76, Totri CR, Eichenfield LF, Logan K, Proudfoot L, Schmitt J, Lara-Corrales I, Sugarman J, Tom W, Siegfried E, Cordoro K, Paller AS, Flohr C, Prescribing practices for systemic agents in the treatment of severe pediatric atopic dermatitis in the US and Canada: The PeDRA TREAT survey, Pages 281-285, Copyright 2016, with permission from Elsevier. Table 2 is reprinted from Clinics in Dermatology, Vol 33, Slater NA, Morrell DS, Systemic therapy of childhood atopic dermatitis, Pages 289-299, Copyright 2015, with permission from Elsevier. Table 3 is modified from Journal of the American Academy of Dermatology, Vol 82, Lansang P, Bergman JN, Fiorillo L, Joseph M, Lara-Corrales I, Marcoux D, McCuaig C, Pope E, Prajapati VH, Li SZJ, Landells I, Management of pediatric plaque psoriasis using biologics, Pages 213-221, Copyright 2019, with permission from Elsevier.
Co-Authors Aldri Frinaldi Githa Rahmayunita Henry W. Lim Henry W. Lim Rinadewi Astriningrum Rinadewi Astriningrum Shanthi Narla Shanthi Narla Tor Shwayder Tor Shwayder