Introduction: Organophosphorus poisoning is an important medical emergency and its pattern and outcomevaries from place to place. Given the widespread availability and use of these chemicals, OP poisoning isquite common following either accidental or intentional exposures.Aims and Objective: This study was conducted to evaluate the spectrum of acute poisoning in a tertiarycare hospital.Materials and Methods: This is a retrospective study of organophosphorus poisoning cases brought toemergency department/casualty of a tertiary care hospital from Jan 2011 to Dec 2014. Result: Total 805cases of acute poisoning were recorded over aperiod of 4 years. Acute poisoning was common in men, andage group of 20–40 years was the most affected. The most common offending population was poor class (V)and financial burden was the most common reason noted.Conclusion: From these results we found that Organo Phosphorous compounds are commonly ingested withsuicidal intent due to its easy availability by young population in rural areas, more commonly males witheconomical burdens