Tariq Soyab
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Journal : Indian Journal of Forensic Medicine

Genes Associated with Fibro-Osseous Lesion: A Review Article Tariq Soyab
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.13058

Abstract

The Fibro osseous lesion is a group of diseases or lesions that are affecting the skeletal tissue which frequentlyincludes maxilla and mandible. The disease can also be easily described as bone disorders. A lot of researchand work has been done regarding this serious disease though due to similarities in its radiographical featuresor histopathology, it is been very complicating to diagnose and classify FOLs. The review article focuses ondifferent diseases that come under the fibro-osseous lesion and the genes which have been associated withthe respective one in an orderly manner with their Histopathological features. One to understand this lesionthe clinical correlation with radiographic involvement is necessary to diagnose this kind of dysplasia. Thearticle also throws light on that the mandible and maxilla also suffer from localized and generalized formsof skeletal dysplasia which results in disproportionate short stature. These dysplasias always remain in aconfused manner for their nomenclature. Much classification has been proposed by the different authors indifferent years regarding the FOLs based on gene or protein defect in these disorders.
Special Stains Used in Histopathological Techniques: A Brief View Tariq Soyab
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.13059

Abstract

The routine staining which is also called as H & E staining (Hematoxylin and eosin) is the most widely usedstain in the laboratories or histopathology laboratory. In this procedure the nuclear protein stains purpleand the cytoplasm and any other substances stains as red or orange. It plays a very crucial role in medicaldiagnosis or research where the specimen or tissue is been sent for processing. The staining procedure isperformed by trained professionals and after which the role of highly trained pathologists and researcherscome, which under the microscope view the specific structures, cells and even microorganisms to providea diagnosis for the specific disease. The special stains are those which come under the special stainingtechnique or alternative method for the H & E stains, where H & E staining does not provide the properidentification or appreciation of certain normal and abnormal tissue or structure which the pathologist orresearchers needs. This article throws light on the Special stains which are been used in histopathologicalprocedures in which these abnormal or normal tissues can be properly appreciated. The article also focuseson the procedure, principle and uses of these special stains in their respective field.
Salivary Glands: A Brief View on Types, Anatomy & Histological Features Tariq Soyab
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.13129

Abstract

Salivary glands are crucial organs playing a vital role in the secretion of saliva in the oral cavity. Duringits morphogenesis a sequel of coordinated movements that are developmental processes occurred and theinteraction of mesenchyme and epithelium generating the ductal system and secretory units. Salivary glandsconsist of major and minor glands that play different roles in saliva secretion. The maximum cell types ofsalivary glands are innervated by parasympathetic and sympathetic nerves. Histologically serous acini andmucous acini cell types can be seen with a network of the ductal system which includes striated, excretoryand intercalated ducts, the external carotid artery maintain the blood supply of major salivary glands andthe role of vasculature supply remaining unclear regarding the maintenance of saliva secretion which needsfurther investigation. The article throws light on its different types, its histological features, and its ductalsystem.
Red and White Lesions of the Oral Cavity: An Update Tariq Soyab
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.13132

Abstract

In our oral cavity various pathological conditions have been reported which includes different type of lesionswhich require a proper diagnostic criteria, clinically correlation including radiographic & histological reportsfor its diagnosis. In this article we focus on the various types of red and white lesions of the oral cavity whichhave been classified based on its etiology, variation in structure, appearance, precancerous potentiality &etc. The lesion appears white due to changes in the epithelium which can be caused by an increase in thekeratinization of normal keratinized mucosa, keratinization of non keratinized mucosa or thickening of theepithelium. The reduced vascularity or fibrosis of mucosa can also lead to the whiteness of the oral mucosa.The red appearance of the lesion appears because of the inflammation,atrophy, vascular dilation, and purpuraor reduced in the keratinization of the oral epithelium. Generally the red and white lesions are benign and alarge proportion of the normal population has been affected by it. The most common precancerous conditionwhich comes under these lesions classification is Leukoplakia. A proper management of this condition isrequired to avoid its future complication. All conditions should be properly examined by taking a proper andcareful history. However a biopsy is much needed for these conditions to be diagnosed accurately